Marcel Michla
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View article: TCR-dependent CD8+ T cell responses drive atherosclerotic plaque instability 2443
TCR-dependent CD8+ T cell responses drive atherosclerotic plaque instability 2443 Open
Description Atherosclerosis is a chronic inflammatory condition of the arterial vasculature. The rupture of atherosclerotic plaques, leading to myocardial infarctions, underpins most cardiovascular disease-related morbidity and mortality. …
View article: CTLA-4-Ig therapy preserves cardiac function following myocardial infarction with reperfusion
CTLA-4-Ig therapy preserves cardiac function following myocardial infarction with reperfusion Open
Aims T cells drive adverse cardiac inflammation and ischemia-reperfusion injury following myocardial infarction (MI). Here, we aimed to test the extent to which T cell inhibition protected cardiac function following MI in mice. Methods and…
View article: Food for thought – ILC metabolism in the context of helminth infections
Food for thought – ILC metabolism in the context of helminth infections Open
Helminths are multicellular ancient organisms residing as parasites at mucosal surfaces of their host. Through adaptation and co-evolution with their hosts, helminths have been able to develop tolerance mechanisms to limit inflammation and…
View article: Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19
Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19 Open
View article: Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation
Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation Open
View article: Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation
Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation Open