Marcel Schubert
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Biointegrated microlasers: technologies, applications, and emerging developments Open
Laser light is one of the greatest and most versatile technologies ever invented. Recent developments in the miniaturization of lasers have opened up the possibility of directly interfacing living biological cells with microscopic lasers. …
Biologische und biomedizinische Anwendungen intrazellularer Laserpartikel Open
Microscopic laser particles have emerged as a new type of intracellular probes for various biological and biomedical applications. Utilizing some of the unique properties of laser light, laser particles are formidable barcoding devices, ca…
DNA Sensing with Whispering Gallery Mode Microlasers Open
Nucleic acid sensing is crucial for advancing diagnostics, therapeutic monitoring, and molecular biology research by enabling the precise identification of DNA and RNA interactions. Here, we present an innovative sensing platform based on …
Monitoring microplastics in live reef-building corals with microscopic laser particles Open
Micro- and nanoplastics pose a growing threat to marine organisms, such as reef-building corals. Yet, our understanding of microplastic uptake, interaction with coral tissue, and incorporation into coral skeletons remains limited, mainly d…
DNA Sensing with Whispering Gallery Mode Microlasers Open
Nucleic acid sensing is crucial for advancing diagnostics, therapeutic monitoring and molecu-lar biology research, by enabling the precise identification of DNA and RNA interactions. Here, we present an innovative sensing platform based on…
Optically Manipulated Micromirrors for Precise Excitation of WGM Microlasers Open
Whispering gallery mode microlasers are highly sensitive refractive index sensors widely explored for biophotonic and biomedical applications. Microlaser excitation and collection of the emitted light typically utilize microscope objective…
Optically manipulated micromirrors for precise excitation of WGM microlasers Open
Whispering gallery mode microlasers are highly sensitive refractive index sensors widely explored for biophotonic and biomedical applications. Microlaser excitation and collection of the emitted light typically utilize microscope objective…
Hyperspectral Confocal Imaging for High-Throughput Readout and Analysis of Bio-Integrated Laser Particles Open
Integrating laser particles into live cells, tissue cultures, and small animals is an emerging and rapidly evolving technique that offers non-invasive interrogation and labelling with unprecedented information density. The bright and disti…
View article: Local Sensing of Absolute Refractive Index During Protein‐Binding using Microlasers with Spectral Encoding
Local Sensing of Absolute Refractive Index During Protein‐Binding using Microlasers with Spectral Encoding Open
Multiplexed, specific, and sensitive detection of antigens is critical for the rapid and accurate diagnosis of disease and the informed development of personalized treatment plans. Here, it is shown that polymer microsphere lasers can be u…
Local sensing of absolute refractive index during protein-binding using microlasers with spectral encoding Open
Multiplexed, specific and sensitive detection of antigens is critical for the rapid and accurate diagnosis of disease and the informed development of personalized treatment plans. Here, we show that polymer microsphere lasers can be used a…
Red-Shifted Excitation and Two-Photon Pumping of Biointegrated GaInP/AlGaInP Quantum Well Microlasers Open
Biointegrated intracellular microlasers have emerged as an attractive and versatile tool in biophotonics. Different inorganic semiconductor materials have been used for the fabrication of such biocompatible microlasers but often operate at…
View article: Distributed Feedback Lasers Based on Green Fluorescent Protein and Conformal High Refractive Index Oxide Layers
Distributed Feedback Lasers Based on Green Fluorescent Protein and Conformal High Refractive Index Oxide Layers Open
Fluorescent proteins have emerged as an attractive gain material for lasers, especially for devices requiring biocompatibility. However, due to their optical properties, integration with distributed feedback (DFB) resonators is not readily…
Microlaser-based contractility sensing in single cardiomyocytes and whole hearts Open
Microscopic whispering gallery mode lasers detect minute changes in cellular refractive index inside individual cardiac cells and in live zebrafish. We show that these signals encode cardiac contractility that can be used for intravital se…
Investigating the diversity of Type Ia supernova spectra with the open-source relational data base kaepora Open
We present a public, open-source relational data base (we name kaepora) containing a sample of 4975 spectra of 777 Type Ia supernovae (SNe Ia). Since we draw from many sources, we significantly improve the spectra by inspecting these data …
Single cell induced optical confinement in biological lasers Open
Biological single cell lasers have shown great potential for fundamental research and next generation sensing applications. In this study, the potential of fluorescent biological cells as refractive index landscapes and active optical elem…
Lasing in Live Mitotic and Non-Phagocytic Cells by Efficient Delivery of Microresonators Open
Reliable methods to individually track large numbers of cells in real time are urgently needed to advance our understanding of important biological processes like cancer metastasis, neuronal network development and wound healing. It has re…
Fluorescent Proteins: Strong Coupling in Fully Tunable Microcavities Filled with Biologically Produced Fluorescent Proteins (Advanced Optical Materials 1/2017) Open
Biologically produced fluorescent protein molecules emitting green or red light are mixed and inserted into high quality optical resonators, by C. P. Dietrich, S. Höfling, M. C. Gather, and co-workers in article number 1600659, to study st…
Strong Coupling in Fully Tunable Microcavities Filled with Biologically Produced Fluorescent Proteins Open
We thank C. Schneider for fruitful discussions and A. Clemens and K. Ostermann (TU Dresden, Germany) for technical support with protein preparation. We acknowledge financial support from the European Research Council (ERC StG ABLASE, 64001…
An exciton-polariton laser based on biologically produced fluorescent protein Open
Microcavities filled with biologically produced green fluorescent protein show polariton condensation at room temperature.
Optofluidic distributed feedback lasers with evanescent pumping: Reduced threshold and angular dispersion analysis Open
We demonstrate an evanescently pumped water-based optofluidic distributed feedback (DFB) laser with a record low pump threshold of ETH=520 nJ. The low threshold results from an optimized mode shape, which is achieved by a low refractive in…