Marcelino Cortés
YOU?
Author Swipe
View article: Troxerutin is a novel osmotic agent for peritoneal dialysis with protective cardiovascular actions
Troxerutin is a novel osmotic agent for peritoneal dialysis with protective cardiovascular actions Open
Background and hypothesis End-stage renal disease patients require peritoneal dialysis (PD) as a life-saving therapy; however, they continue to experience systemic inflammation and increased cardiovascular pathology. These complications ca…
View article: Klotho plasma levels are an independent predictor of mortality in women with acute coronary syndrome
Klotho plasma levels are an independent predictor of mortality in women with acute coronary syndrome Open
Alterations in plasma levels of the components of the mineral metabolism (MM) system are related to cardiovascular diseases. However, gender differences of the whole MM system in patients with acute coronary syndrome (ACS) have not been re…
View article: Klotho plasma levels are an independent predictorof mortality in women with acute coronary syndrome
Klotho plasma levels are an independent predictorof mortality in women with acute coronary syndrome Open
Alterations in plasma levels of the components of the mineral metabolism (MM) system are related to cardiovascular diseases. However, gender differences of the whole MM system in patients with acute coronary syndrome (ACS) have not been re…
View article: QRS fragmentation as a predictor of clinical events in patients undergoing cardiac resynchronization therapy
QRS fragmentation as a predictor of clinical events in patients undergoing cardiac resynchronization therapy Open
Background QRS fragmentation (QRSf) has been associated with a worse prognosis in several cardiac diseases, although limited evidence exists on QRSf in patients undergoing cardiac resynchronization therapy (CRT). Objectives This study aime…
View article: New Biomarkers in the Prognostic Assessment of Acute Heart Failure with Reduced Ejection Fraction: Beyond Natriuretic Peptides
New Biomarkers in the Prognostic Assessment of Acute Heart Failure with Reduced Ejection Fraction: Beyond Natriuretic Peptides Open
Natriuretic peptides are established biomarkers related to the prognosis of heart failure. New biomarkers have emerged in the field of cardiovascular disease. The prognostic value of these biomarkers in heart failure with reduced left vent…
View article: New Biomarkers in the Prognostic Assessment of Acute Heart Failure with Reduced Ejection Fraction: Beyond Natriuretic Peptides
New Biomarkers in the Prognostic Assessment of Acute Heart Failure with Reduced Ejection Fraction: Beyond Natriuretic Peptides Open
Natriuretic peptides are established biomarkers related to the prognosis of heart failure.New biomarkers have emerged in the area of cardiovascular disease. The prognostic value of these biomarkers in heart failure with reduced LVEF (HFrEF…
View article: FDG‐PET and Amyloid PET scans: benefits beyond Alzheimer´s Disease. It´s really useful in daily practice? Clinical case review
FDG‐PET and Amyloid PET scans: benefits beyond Alzheimer´s Disease. It´s really useful in daily practice? Clinical case review Open
Background biomarkers are essential in order to make a diagnosis with a high level of accuracy in patients with cognitive and behavior complaints. However, molecular imaging biomarkers not always provide an answer in daily clinical practic…
View article: Klotho plasma levels are an independent predictor of mortality in women with acute coronary syndrome
Klotho plasma levels are an independent predictor of mortality in women with acute coronary syndrome Open
INTRODUCTION Alterations in plasma levels of the components of the mineral metabolism (MM) system (calcidiol, fibroblast growth factor-23 [FGF23], phosphate, parathormone [PTH] and klotho) are related to cardiovascular diseases. However, g…
View article: Impact of QRS complex fragmentation on all-cause mortality before and after cardiac resynchronization therapy
Impact of QRS complex fragmentation on all-cause mortality before and after cardiac resynchronization therapy Open
Introduction Cardiac resynchronization therapy (CRT) have demonstrated to reduce all-cause mortality in selected patients with HFrEF. However, there is still a high rate of non-responders, so risk stratification is crucial. Fragmentation o…
View article: The impact of QRS complex fragmentation status before and after cardiac resynchronization therapy with defibrillator implantation: Is it a predictor of arrhythmic events?
The impact of QRS complex fragmentation status before and after cardiac resynchronization therapy with defibrillator implantation: Is it a predictor of arrhythmic events? Open
Introduction Cardiac resynchronization therapy with an implantable cardioverter defibrillator (CRT-D) has demonstrated efficacy in reducing mortality, hospitalization for heart failure (HF), and sudden cardiac death among subgroups of pati…
View article: Ccn2 Deletion Reduces Cardiac Dysfunction, Oxidative Markers, and Fibrosis Induced by Doxorubicin Administration in Mice
Ccn2 Deletion Reduces Cardiac Dysfunction, Oxidative Markers, and Fibrosis Induced by Doxorubicin Administration in Mice Open
Cellular Communication Network Factor 2 (CCN2) is a matricellular protein implicated in cell communication and microenvironmental signaling. Overexpression of CCN2 has been documented in various cardiovascular pathologies, wherein it may e…
View article: Use and Benefit of Sacubitril/Valsartan in Elderly Patients with Heart Failure with Reduced Ejection Fraction
Use and Benefit of Sacubitril/Valsartan in Elderly Patients with Heart Failure with Reduced Ejection Fraction Open
Background: Heart failure (HF) is a highly prevalent syndrome in elderly subjects. Currently, multiple drugs have shown clinical benefits in patients with HF and reduced ejection fraction (HFrEF). However, evidence is scarce in elderly pat…
View article: Impact of SGLT2 Inhibitors on Very Elderly Population with Heart Failure with Reduce Ejection Fraction: Real Life Data
Impact of SGLT2 Inhibitors on Very Elderly Population with Heart Failure with Reduce Ejection Fraction: Real Life Data Open
(1) Background: The validation of new lines of therapy for the elderly is required due to the progressive ageing of the world population and scarce evidence in elderly patients with HF with reduced ejection fraction (HFrEF). The purpose of…
View article: Role of fragmented QRS complex in the prognosis of patients undergoing cardiac resynchronization therapy. A new red flag to look for?
Role of fragmented QRS complex in the prognosis of patients undergoing cardiac resynchronization therapy. A new red flag to look for? Open
Introduction Cardiac resynchronization therapy (CRT) has demonstrated to reduce mortality and hospitalization for heart failure in selected patients with heart failure with reduced ejection fraction (HFrEF). However, there is a significant…
View article: Daytime blood pressure measurements performed by a cuffless blood pressure monitor compared to 24-hour ambulatory blood pressure monitor: preliminary comparative results of a single-centre study
Daytime blood pressure measurements performed by a cuffless blood pressure monitor compared to 24-hour ambulatory blood pressure monitor: preliminary comparative results of a single-centre study Open
Background Ambulatory blood pressure (BP) monitors (ABPM) measure systolic and diastolic BP (SBP, DBP), limited to 24-48-hour snapshots, using uncomfortable cuff-based oscillometric sphygmomanometers. Some cuffless BP devices overcome thes…
View article: Effect of sodium-glucose type 2 cotransporter inhibitors on cardiac structure and function in patients with normal ejection fraction
Effect of sodium-glucose type 2 cotransporter inhibitors on cardiac structure and function in patients with normal ejection fraction Open
Introduction Sodium-glucose cotransporter inhibitors (SGLT2i) have proven a reduction in cardiovascular events in diabetic patients with and without heart failure (HF), as well as in non-diabetic patients with heart failure with reduced an…
View article: Fragmented QRS complex as a predictor of appropriate shocks in patients undergoing cardiac resynchronization therapy and defibrillator. A chronicle of a shock foretold?
Fragmented QRS complex as a predictor of appropriate shocks in patients undergoing cardiac resynchronization therapy and defibrillator. A chronicle of a shock foretold? Open
Introduction Cardiac resynchronization therapy (CRT) has demonstrated to reduce mortality and hospitalization for heart failure in patients with heart failure with reduced ejection fraction (HFrEF) in specific subgroups of patients Moreove…
View article: Fragmented QRS complex as a predictor of all-cause mortality in patients undergoing cardiac resynchronization therapy
Fragmented QRS complex as a predictor of all-cause mortality in patients undergoing cardiac resynchronization therapy Open
Introduction Heart failure with reduced left ventricle ejection fraction (HFrEF) is a prevalent entity with poor prognosis in the follow-up. Cardiac resynchronization therapy (CRT) in specific situations, have demonstrated to reduce all-ca…
View article: Dapagliflozin Improved Cardiac Function and Structure in Diabetic Patients with Preserved Ejection Fraction: Results of a Single Centre, Observational Prospective Study
Dapagliflozin Improved Cardiac Function and Structure in Diabetic Patients with Preserved Ejection Fraction: Results of a Single Centre, Observational Prospective Study Open
Sodium-glucose cotransporter inhibitors (SGLT2i) have demonstrated a reduction in cardiovascular events in diabetes and heart failure (HF). The mechanisms underlying this benefit are not well known and data are contradictory. The purpose o…
View article: SGLT2 inhibitors effects on cardiac function and plasma biomarkers of diabetic patients with preserved ejection fraction
SGLT2 inhibitors effects on cardiac function and plasma biomarkers of diabetic patients with preserved ejection fraction Open
BACKGROUND Sodium-glucose cotransporter inhibitors (SGLT2i) have proven a reduction in cardiovascular events in diabetic patients with and without heart failure (HF), as well as in non-diabetic patients with HF. The mechanisms underlying t…
View article: Pulmonary vein anatomy evaluated prior to atrial fibrillation ablation through multicentre electronic medical records: clinical decision support from a real-world multicentre observational study
Pulmonary vein anatomy evaluated prior to atrial fibrillation ablation through multicentre electronic medical records: clinical decision support from a real-world multicentre observational study Open
Funding Acknowledgements Type of funding sources: None. Background Pulmonary vein (PV) isolation is a cornerstone ablation strategy in the management of patients with atrial fibrillation (AF). PV frequently display anatomical variants, whi…
View article: The Synthetic Flavonoid Hidrosmin Improves Endothelial Dysfunction and Atherosclerotic Lesions in Diabetic Mice
The Synthetic Flavonoid Hidrosmin Improves Endothelial Dysfunction and Atherosclerotic Lesions in Diabetic Mice Open
In diabetes, chronic hyperglycemia, dyslipidemia, inflammation and oxidative stress contribute to the progression of macro/microvascular complications. Recently, benefits of the use of flavonoids in these conditions have been established. …
View article: Sacubitril valsartan in aged patients with heart failure and reduced ejection fraction: a safe and beneficial therapy
Sacubitril valsartan in aged patients with heart failure and reduced ejection fraction: a safe and beneficial therapy Open
Background Heart failure (HF) constitutes a prevalent diagnosis in aged patients. During the last decades, several therapies have demonstrated clinical benefits among patients with HF and left ventricular systolic disfunction (LVSD), inclu…
View article: Is bilateral lung transplantation in pulmonary artery hypertension related to congenital heart disease a real therapeutic option? Experience of a national referral centre
Is bilateral lung transplantation in pulmonary artery hypertension related to congenital heart disease a real therapeutic option? Experience of a national referral centre Open
Background Pulmonary arterial hypertension (PAH) affects almost 10% of patients with congenital heart disease, markedly worsening their prognosis. Bilateral lung or cardiopulmonary transplantation is therefore the last therapeutic option. …
View article: Outcomes of sodium-glucose co-transporter type 2 inhibitors use in elderly patients with heart failure with reduced ejection fraction
Outcomes of sodium-glucose co-transporter type 2 inhibitors use in elderly patients with heart failure with reduced ejection fraction Open
Background Heart failure is a highly prevalent condition, especially in patients over 75 years. In recent years, new therapeutic lines have emerged for the management of heart failure with reduced ejection fraction (HFrEF), most notably so…
View article: Beta-blocker therapy in elderly patients with renal dysfunction and heart failure.
Beta-blocker therapy in elderly patients with renal dysfunction and heart failure. Open
The use of BB in elderly patients with HFrEF and renal impairment was associated with a better prognosis. Use of BB should be encouraged when possible.
View article: P6295Relationship between different doses of angiotensin-converting enzyme inhibitors/angiotensin receptor blockers and prognosis in elderly patients with low ejection fraction and chronic kidney disease
P6295Relationship between different doses of angiotensin-converting enzyme inhibitors/angiotensin receptor blockers and prognosis in elderly patients with low ejection fraction and chronic kidney disease Open
The aim of the study was to evaluate the influence of Frailty on the one-year outcomes in elderly patients presented with ACS.Methods: The study was organized as a registry of consequent patients who were admitted to the hospital with ACS …