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View article: Neoadjuvant Under‐Dilated <scp>TIPS</scp> : Expanding Surgeries for Extrahepatic Malignancies in Patients With Cirrhosis and <scp>CSPH</scp>
Neoadjuvant Under‐Dilated <span>TIPS</span> : Expanding Surgeries for Extrahepatic Malignancies in Patients With Cirrhosis and <span>CSPH</span> Open
Background & Aims Portal hypertension is a major challenge in patients with cirrhosis requiring surgery. This study aimed to evaluate the efficacy of under‐dilated neoadjuvant transjugular intrahepatic portosystemic shunt (U.N‐TIPS) in ena…
View article: Predicting hepatic decompensation using non-invasive tests in a contemporary multicentre cohort of patients with cACLD
Predicting hepatic decompensation using non-invasive tests in a contemporary multicentre cohort of patients with cACLD Open
Non-invasive tests (NITs) facilitate the early diagnosis and management of clinically significant portal hypertension (CSPH) in patients with compensated advanced chronic liver disease (cACLD) patients. In our contemporary cohort of cACLD …
View article: Concomitant Autoimmune Liver Disease and Hepatic Actinomycosis: A Diagnostic Challenge—Brief Report and Review of the Literature
Concomitant Autoimmune Liver Disease and Hepatic Actinomycosis: A Diagnostic Challenge—Brief Report and Review of the Literature Open
Hepatic actinomycosis (HA) and IgG4-related inflammatory pseudotumors are rare and often overlooked causes of liver mass, which can easily be misdiagnosed as primary liver cancer or metastasis. Diagnosis is arduous due to unspecified clini…
View article: End-procedural adherence to recommended hemodynamic targets does not improve the outcome of elective TIPS in patients with cirrhosis
End-procedural adherence to recommended hemodynamic targets does not improve the outcome of elective TIPS in patients with cirrhosis Open
Background and Aims: In clinical practice, the reduction of portocaval pressure gradient (PCPG) following TIPS does not always meet the recommendation of current guidance. We evaluated the impact of different degrees of PCPG reduction, mea…
View article: Post-trans-arterial chemoembolization hepatic necrosis and biliary stenosis: Clinical charateristics and endoscopic approach
Post-trans-arterial chemoembolization hepatic necrosis and biliary stenosis: Clinical charateristics and endoscopic approach Open
Liver cancer is the fifth most common tumor and the second highest death-related cancer in the world. Hepatocarcinoma (HCC) represents 90% of liver cancers. According to the Barcelona Clinic Liver Cancer group, different treatment options …
View article: Transjugular Intrahepatic Portosystemic Shunt: Devices Evolution, Technical Tips and Future Perspectives
Transjugular Intrahepatic Portosystemic Shunt: Devices Evolution, Technical Tips and Future Perspectives Open
Portal hypertension (PH) constitutes a pivotal factor in the progression of cirrhosis, giving rise to severe complications and a diminished survival rate. The transjugular intrahepatic portosystemic shunt (TIPS) procedure has undergone sig…
View article: Mortality after transjugular intrahepatic portosystemic shunt in older adult patients with cirrhosis: A validated prediction model
Mortality after transjugular intrahepatic portosystemic shunt in older adult patients with cirrhosis: A validated prediction model Open
Background and Aims: Implantation of a transjugular intrahepatic portosystemic shunt (TIPS) improves survival in patients with cirrhosis with refractory ascites and portal hypertensive bleeding. However, the indication for TIPS in older ad…
View article: Portosystemic shunt is an effective treatment for complications of portal hypertension in hepatic myeloid metaplasia and improves nutritional status
Portosystemic shunt is an effective treatment for complications of portal hypertension in hepatic myeloid metaplasia and improves nutritional status Open
In patients affected by myelofibrosis with hepatic myeloid metaplasia (HMM), portal hypertension (PHT) complications may develop. In this case series, we analysed the efficacy and safety of transjugular portosystemic shunt (TIPS) in the tr…
View article: Proximal Splenic Artery Embolization to Treat Refractory Ascites in a Patient With Cirrhosis
Proximal Splenic Artery Embolization to Treat Refractory Ascites in a Patient With Cirrhosis Open
Since the early 1970s several studies have reported distal splenic artery embolization, better known as partial spleen embolization (PSE), as an efficacious treatment of portal hypertensive variceal bleeding and hypersplenism in cirrhosis.…
View article: Relevance of Spontaneous Portosystemic Shunts Detected with CT in Patients with Cirrhosis
Relevance of Spontaneous Portosystemic Shunts Detected with CT in Patients with Cirrhosis Open
Background Cirrhosis leads to portal hypertension and to the consequent formation of spontaneous portosystemic shunts (SPSSs), leading to complications related to the diversion of portal blood into the systemic circulation, which is called…
View article: Dynamic angiopoietin-2 assessment predicts survival and chronic course in hospitalized patients with COVID-19
Dynamic angiopoietin-2 assessment predicts survival and chronic course in hospitalized patients with COVID-19 Open
This study examined the association between dynamic angiopoietin-2 assessment and COVID-19 short- and long-term clinical course. We included consecutive hospitalized patients from 1 February to 31 May 2020 with laboratory-confirmed COVID-1…
View article: Guide-wire replacement of a mini-midline catheter with a central venous catheter: A retrospective study on 63 cases
Guide-wire replacement of a mini-midline catheter with a central venous catheter: A retrospective study on 63 cases Open
Background: Achieving a reliable venous access in a particular subset of patients and/or in emergency settings can be challenging and time-consuming. Furthermore, many hospitalized patients do not meet the criteria for central venous cathe…
View article: Use of jugular catheter JLB® as introducer for central venous catheterization in emergency conditions
Use of jugular catheter JLB® as introducer for central venous catheterization in emergency conditions Open
The use of central venous catheterization (CVC) is now a routine clinical practice in critical patient but the insertion technique is not risk-free. The most common complications are failure to place the CVC or improper positioning, accide…
View article: A new device for ultrasound-guided peripheral venous access
A new device for ultrasound-guided peripheral venous access Open
Background: In patients with difficult peripheral venous access, alternative techniques require expertise and are invasive, expensive, and prone to serious adverse events. This brought us to designing a new venous catheter (JLB® Deltamed, …
View article: Liver Angiopoietin‐2 Is a Key Predictor of D e N ovo or Recurrent Hepatocellular Cancer After Hepatitis C Virus Direct‐Acting Antivirals
Liver Angiopoietin‐2 Is a Key Predictor of D e N ovo or Recurrent Hepatocellular Cancer After Hepatitis C Virus Direct‐Acting Antivirals Open
Recent reports suggested that direct acting antivirals (DAAs) might favor hepatocellular carcinoma (HCC). In study 1, we studied the proangiogenic liver microenvironment in 242 DAA‐treated chronic hepatitis C patients with advanced fibrosi…
View article: Low molecular weight heparin does not increase bleeding and mortality post‐endoscopic variceal band ligation in cirrhotic patients
Low molecular weight heparin does not increase bleeding and mortality post‐endoscopic variceal band ligation in cirrhotic patients Open
Background & Aims Anticoagulants are commonly indicated in cirrhotic patients due to high rate of (pro)thrombotic conditions. Low molecular weight heparin ( LMWH ) is safe in patients with esophageal varices. However, the safety of LMWH is…
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Potential conflict of interest: Nothing to report. We read with interest the correspondence from Amarapurkar and Lo. We thank Dr. Amarapurkar et al. for their comments. We certainly agree that, based on the evidence, there is no need to co…
View article: P213. Predicting outcome of paediatric Crohn’s disease: role of clinical, endoscopic, and imaging findings at the diagnosis
P213. Predicting outcome of paediatric Crohn’s disease: role of clinical, endoscopic, and imaging findings at the diagnosis Open
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View article: Complete resolution of non‐necrotizing lung granuloma and pyoderma gangrenosum after restorative proctocolectomy in a woman with severe ulcerative colitis and cytomegalovirus infection
Complete resolution of non‐necrotizing lung granuloma and pyoderma gangrenosum after restorative proctocolectomy in a woman with severe ulcerative colitis and cytomegalovirus infection Open
Key Clinical Message Here, we report the unusual case of an ulcerative colitis female patient presenting together with cytomegalovirus infection, pyoderma gangrenosum and a noncaseating lung granuloma, both resistant to immunomodulatory dr…
View article: Thromboelastographic reference ranges for a cirrhotic patient population undergoing liver transplantation
Thromboelastographic reference ranges for a cirrhotic patient population undergoing liver transplantation Open
The range and distribution of TEG values in cirrhotic patients differ from those of healthy subjects, suggesting that a specific thromboelastographic reference range is required for liver transplant candidates.