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View article: Au@Fe₃O₄@PEG nanocubes as photoactive agents in photothermal therapy: An in vitro study
Au@Fe₃O₄@PEG nanocubes as photoactive agents in photothermal therapy: An in vitro study Open
Photothermal therapy (PTT) is an emerging cancer treatment that utilizes near-infrared (NIR) light and photoactive agents to induce localized hyperthermia, leading to cancer cell destruction. Magnetic nanoparticles (MNPs) with plasmonic pr…
View article: Nanoparticles in wastewater: A comprehensive approach to understanding their ecotoxicity and genotoxicity
Nanoparticles in wastewater: A comprehensive approach to understanding their ecotoxicity and genotoxicity Open
Herein, we investigated the impact of wastewater-borne Al₂O₃ nanoparticles (Al₂O₃NPs) on the aquatic organism Daphnia magna, focusing on both ecotoxicity and genotoxicity. The widespread use of nanoparticles (NPs) in various industries has…
View article: PET Foils Functionalized with Reactive Copolymers as Adaptable Microvolume ELISA Spot Array Platforms for Multiplex Serological Analysis of SARS-CoV-2 Infections
PET Foils Functionalized with Reactive Copolymers as Adaptable Microvolume ELISA Spot Array Platforms for Multiplex Serological Analysis of SARS-CoV-2 Infections Open
Microvolume ELISA platforms have become vital in diagnostics for their high-throughput capabilities and minimal sample requirements. High-quality substrates with advanced surface properties are essential for these applications. They enable…
View article: Novel Applications of CE‐ICP‐MS/MS: Monitoring of Antiaging GHK–Cu Cosmetic Component Encapsulation in Liposomes
Novel Applications of CE‐ICP‐MS/MS: Monitoring of Antiaging GHK–Cu Cosmetic Component Encapsulation in Liposomes Open
The hyphenation of the separation technique with the high‐sensitive mass spectrometry detection is one of the driving forces of modern analysis enabling measurements in complex matrices. In particular, capillary electrophoresis coupled to …
View article: Kinetics of the thermal decomposition of thermally reduced graphene oxide treated with a pulsed high-frequency discharge in hydrogen atmosphere
Kinetics of the thermal decomposition of thermally reduced graphene oxide treated with a pulsed high-frequency discharge in hydrogen atmosphere Open
Thermal stability and the kinetics of thermal decomposition of the thermally reduced graphene oxide (TRGO) treated by a pulsed high-frequency discharge in a hydrogen atmosphere have been studied. The modified Hummers method was used for ob…
View article: A Careful Insight into DDI-Type Receptor Layers on the Way to Improvement of Click-Biology-Based Immunosensors
A Careful Insight into DDI-Type Receptor Layers on the Way to Improvement of Click-Biology-Based Immunosensors Open
Protein-based microarrays are important tools for high-throughput medical diagnostics, offering versatile platforms for multiplex immunodetection. However, challenges arise in protein microarrays due to the heterogeneous nature of proteins…
View article: Correction: Optimization of a CE-ICP-MS/MS method for the investigation of liposome–cisplatin nanosystems and their interactions with transferrin
Correction: Optimization of a CE-ICP-MS/MS method for the investigation of liposome–cisplatin nanosystems and their interactions with transferrin Open
Correction for ‘Optimization of a CE-ICP-MS/MS method for the investigation of liposome–cisplatin nanosystems and their interactions with transferrin’ by Anna Maria Wróblewska et al. , J. Anal. At. Spectrom. , 2022, 37 , 1442–1449, https:/…
View article: Study on Saccharide–Glucose Receptor Interactions with the Use of Surface Plasmon Resonance
Study on Saccharide–Glucose Receptor Interactions with the Use of Surface Plasmon Resonance Open
The aim of this study was to investigate the process of attachment of saccharide particles differing in degree of complexity to cell receptors responsible for transport of glucose across the cell membrane (GLUT proteins). This phenomenon i…
View article: Magnetic polyurethane nanomaterials: A novel approach for in vitro cardiac cell maturation and culture
Magnetic polyurethane nanomaterials: A novel approach for in vitro cardiac cell maturation and culture Open
In this study, we have investigated how new composite material (magnetic polyurethane (PU) nanofibers) influences the culture and maturation of cardiomyocyte cells. Magnetic iron (II, III) oxide nanoparticles (Fe3O4, MNPs) were incorporate…
View article: Au-X (X=Pt/Ru)-decorated magnetic nanocubes as bifunctional nanozyme labels in colorimetric, magnetically-enhanced, one-step sandwich CRP immunoassay
Au-X (X=Pt/Ru)-decorated magnetic nanocubes as bifunctional nanozyme labels in colorimetric, magnetically-enhanced, one-step sandwich CRP immunoassay Open
Scientific interest in the investigation and application of multifunctional nanomaterials in medical diagnostics has been increasing. The employment of magnetocatalytic immunoconjugates as both analyte-capturing agents and enzyme-like cata…
View article: Portable Surface Plasmon Resonance Detector for COVID-19 Infection
Portable Surface Plasmon Resonance Detector for COVID-19 Infection Open
Methods based on nucleic acid detection are currently the most commonly used technique in COVID-19 diagnostics. Although generally considered adequate, these methods are characterised by quite a long time-to-result and the necessity to pre…
View article: Red Flags and Adversities on the Way to the Robust CE-ICP-MS/MS Quantitative Monitoring of Self-Synthesized Magnetic Iron Oxide(II, III)-Based Nanoparticle Interactions with Human Serum Proteins
Red Flags and Adversities on the Way to the Robust CE-ICP-MS/MS Quantitative Monitoring of Self-Synthesized Magnetic Iron Oxide(II, III)-Based Nanoparticle Interactions with Human Serum Proteins Open
The growing interest in superparamagnetic iron oxide nanoparticles (SPIONs) as potential theranostic agents is related to their unique properties and the broad range of possibilities for their surface functionalization. However, despite th…
View article: Miniaturized Immunoplatforms Supporting the Diagnosis of Lung Cancer Biomarkers and Immunotherapies
Miniaturized Immunoplatforms Supporting the Diagnosis of Lung Cancer Biomarkers and Immunotherapies Open
Immunotherapy is an innovative cancer treatment that activates the immune system, enabling natural anti-cancer defense mechanisms. Although the large-scale use of immunological treatment is yet to happen, immunotherapy already plays a prac…
View article: Studies on Recombinant Insulin Analogs Interactions with Partner Cell Membrane Receptors Using the SPR Technique
Studies on Recombinant Insulin Analogs Interactions with Partner Cell Membrane Receptors Using the SPR Technique Open
The rapid progress in the field of chemical sensors has made it possible to carry out quick, accurate, and precise monitoring of interactions between biological compounds, enabling the development of models describing the processes that oc…
View article: Comparative Evaluation of Different Surface Coatings of Fe3O4-Based Magnetic Nano Sorbent for Applications in the Nucleic Acids Extraction
Comparative Evaluation of Different Surface Coatings of Fe3O4-Based Magnetic Nano Sorbent for Applications in the Nucleic Acids Extraction Open
Nucleic acid extraction and purification are crucial steps in sample preparation for multiple diagnostic procedures. Routine methodologies of DNA isolation require benchtop equipment (e.g., centrifuges) and labor-intensive steps. Magnetic …
View article: Versatile and Easily Designable Polyester-Laser Toner Interfaces for Site-Oriented Adsorption of Antibodies
Versatile and Easily Designable Polyester-Laser Toner Interfaces for Site-Oriented Adsorption of Antibodies Open
Laser toners appear as attractive materials for barriers and easily laminated interphases for Lab-on-a-Foil microfluidics, due to the excellent adhesion to paper and various membranes or foils. This work shows for the first time a comprehe…
View article: Targeted Delivery of Cisplatin by Gold Nanoparticles: The Influence of Nanocarrier Surface Modification Type on the Efficiency of Drug Binding Examined by CE-ICP-MS/MS
Targeted Delivery of Cisplatin by Gold Nanoparticles: The Influence of Nanocarrier Surface Modification Type on the Efficiency of Drug Binding Examined by CE-ICP-MS/MS Open
Spherical gold nanoparticles (GNPs), whose unique properties regarding biomedical applications were broadly investigated, are an object of interest as nanocarriers in drug targeted delivery systems (DTDSs). The possibility of surface funct…
View article: Optimization of a CE-ICP-MS/MS method for the investigation of liposome–cisplatin nanosystems and their interactions with transferrin
Optimization of a CE-ICP-MS/MS method for the investigation of liposome–cisplatin nanosystems and their interactions with transferrin Open
This study aims to elaborate on a novel comprehensive CE-ICP-MS/MS method for liposome-based cisplatin delivery system characterization. The optimized method allows for direct monitoring of formation products, the drug loading efficiency, …
View article: Excitation-emission fluorescence matrix acquired from glutathione capped CdSeS/ZnS quantum dots in combination with chemometric tools for pattern-based sensing of neurotransmitters
Excitation-emission fluorescence matrix acquired from glutathione capped CdSeS/ZnS quantum dots in combination with chemometric tools for pattern-based sensing of neurotransmitters Open
The presented work concerns pattern-based sensing with quantum dots for the identification and quantification of neurotransmitters by means of excitation-emission fluorescence spectroscopy (2D fluorescence). In the framework of this study,…
View article: Recent Advancements in Receptor Layer Engineering for Applications in SPR-Based Immunodiagnostics
Recent Advancements in Receptor Layer Engineering for Applications in SPR-Based Immunodiagnostics Open
The rapid progress in the development of surface plasmon resonance-based immunosensing platforms offers wide application possibilities in medical diagnostics as a label-free alternative to enzyme immunoassays. The early diagnosis of diseas…
View article: Nanoparticles of chosen noble metals as reactive oxygen species scavengers
Nanoparticles of chosen noble metals as reactive oxygen species scavengers Open
Reactive oxygen species (ROS) play an important role in various physiological processes of living organisms. However, their increased concentration is usually considered as a threat for our health. Plants, invertebrates, and vertebrates in…
View article: Iron Therapy
Iron Therapy Open
No abstract
View article: Modification of fluorescent nanocrystals with 6-thioguanine: monitoring of drug delivery
Modification of fluorescent nanocrystals with 6-thioguanine: monitoring of drug delivery Open
The purpose of the presented work was to modify the surface of core/shell-type CdSexS1–x/ZnS quantum dots (QDs) with an anticancer drug to form bifunctional nanoconjugate for imaging and drug delivery. 6-Thioguanine (6-TG) which is used to…
View article: SPRi-Based Biosensing Platforms for Detection of Specific DNA Sequences Using Thiolate and Dithiocarbamate Assemblies
SPRi-Based Biosensing Platforms for Detection of Specific DNA Sequences Using Thiolate and Dithiocarbamate Assemblies Open
The framework of presented study covers the development and examination of the analytical performance of surface plasmon resonance-based (SPR) DNA biosensors dedicated for a detection of model target oligonucleotide sequence. For this aim,…