Marcin Kuniewicz
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View article: Cardiac phase variability in pulmonary root geometry: implications for electrophysiological mapping and ablation
Cardiac phase variability in pulmonary root geometry: implications for electrophysiological mapping and ablation Open
The pulmonary root undergoes substantial cardiac cycle-dependent anatomical changes that challenge current mapping system assumptions. These findings have immediate implications for catheter stability, procedural planning, and the developm…
View article: Eustachian valve endocarditis in the context of right atrial embryonic remnants: A systematic review and meta-analysis
Eustachian valve endocarditis in the context of right atrial embryonic remnants: A systematic review and meta-analysis Open
Eustachian valve endocarditis is relatively rare and primarily associated with IVDU and younger age, whereas CVCs and CIEDs are insignificant predictors. Identifying embryonic remnants like the Eustachian valve or Chiari network using echo…
View article: High-resolution 3D visualization of human hearts with emphases on the cardiac conduction system components—a new platform for medical education, mix/virtual reality, computational simulation
High-resolution 3D visualization of human hearts with emphases on the cardiac conduction system components—a new platform for medical education, mix/virtual reality, computational simulation Open
Introduction High-resolution digitized cardiac anatomical data sets are in huge demand in clinical, basic research and computational settings. They can be leveraged to evaluate intricate anatomical and structural changes in disease patholo…
View article: Profiling Reduced Expression of Contractile and Mitochondrial mRNAs in the Human Sinoatrial Node vs. Right Atrium and Predicting Their Suppressed Expression by Transcription Factors and/or microRNAs
Profiling Reduced Expression of Contractile and Mitochondrial mRNAs in the Human Sinoatrial Node vs. Right Atrium and Predicting Their Suppressed Expression by Transcription Factors and/or microRNAs Open
(1) Background: The sinus node (SN) is the main pacemaker of the heart. It is characterized by pacemaker cells that lack mitochondria and contractile elements. We investigated the possibility that transcription factors (TFs) and microRNAs …
View article: Similarities and differences in morphology, CD31 and CD68 expression of male vs. female sinoatrial node and its surrounding atrial muscle in ageing and obesity
Similarities and differences in morphology, CD31 and CD68 expression of male vs. female sinoatrial node and its surrounding atrial muscle in ageing and obesity Open
Research purpose: The sinoatrial node (SN) is the main pacemaker site, and it is located in the junctional area of the superior vena cava within the right atrium (RA). The precise micro-anatomy of the SN in males and females in ageing and …
View article: Electrophysiology lab efficiency using cryoballoon for pulmonary vein isolation in central and eastern Europe: A sub-analysis of the cryo global registry study
Electrophysiology lab efficiency using cryoballoon for pulmonary vein isolation in central and eastern Europe: A sub-analysis of the cryo global registry study Open
In this CEE-specific analysis of EP lab efficiency it was found that 3 cryoballoon ablation procedures could be performed in 1 lab day, leaving time for a 4th simple EP procedure on most days. As such, use cryoballoon ablation for PVI is a…
View article: Anatomical obstacles in cavotricuspid isthmus detected by modified 2D transthoracic echocardiography and long-term outcomes in radiofrequency ablation of typical atrial flutter
Anatomical obstacles in cavotricuspid isthmus detected by modified 2D transthoracic echocardiography and long-term outcomes in radiofrequency ablation of typical atrial flutter Open
Preoperative use of mTTE evaluation helps predict difficulty in cavotricuspid isthmus radiofrequency ablation, thus allowing better planning of the radiofrequency ablation strategy using the most accurate radiofrequency ablation electrode.
View article: Interactive teaching of medical 3D cardiac anatomy: atrial anatomy enhanced by ECG and 3D visualization
Interactive teaching of medical 3D cardiac anatomy: atrial anatomy enhanced by ECG and 3D visualization Open
The most commonly applied way of teaching students to convey the foundations of human anatomy and physiology involves textbooks and lectures. This way of transmitting knowledge causes difficulties for students, especially in the context of…
View article: Morphology of human sinoatrial node and its surrounding right atrial muscle in the global obesity pandemic—does fat matter?
Morphology of human sinoatrial node and its surrounding right atrial muscle in the global obesity pandemic—does fat matter? Open
Introduction The sinus node (SN) is the main pacemaker site of the heart, located in the upper right atrium at the junction of the superior vena cava and right atrium. The precise morphology of the SN in the human heart remains relatively …
View article: ST segment depression in atrioventricular reentrant tachycardia
ST segment depression in atrioventricular reentrant tachycardia Open
Background: ST segment deviation is common in patients with narrow QRS complex tachycardia. It mainly concerns young people in whom ischemic background is unlikely. In our work we would also like to propose another potential mechanism – th…
View article: The anatomy of the atrioventricular nodal artery: A meta‐analysis with implications for cardiothoracic surgery and ablation procedures
The anatomy of the atrioventricular nodal artery: A meta‐analysis with implications for cardiothoracic surgery and ablation procedures Open
The objective of the present meta‐analysis was to evaluate recent and applicable data regarding the location and variation of the atrioventricular nodal artery (AVNA) in relation to adjacent structures. In order to minimize postoperative r…
View article: Permanent single chamber atrial pacing: obsolete or a viable alternative to dual-chamber in selected patients with sinus node disease?
Permanent single chamber atrial pacing: obsolete or a viable alternative to dual-chamber in selected patients with sinus node disease? Open
The reliability of AAI pacing decreases with each year of observation due to development of AF and AVB. However, in the current era of effective AF treatment, the advantages of AAI pacemakers, such as lower incidence of lead malfunction, v…
View article: Radiofrequency catheter ablation of ventricular tachycardia using combined endocardial techniques in patients with structural heart disease improves procedural effectiveness and reduces arrhythmia episodes
Radiofrequency catheter ablation of ventricular tachycardia using combined endocardial techniques in patients with structural heart disease improves procedural effectiveness and reduces arrhythmia episodes Open
VT ablation strategy based on systemic use of combined techniques is effective and safe in long-term follow-up of patients with SHD.
View article: Compound motor action potentials in transient and persistent phrenic nerve injury — metanalysis
Compound motor action potentials in transient and persistent phrenic nerve injury — metanalysis Open
The right phrenic nerve is vulnerable to injury (PNI) during cryoballoon ablation (CBA) isolation of the right pulmonary veins. The complication can be transient or persistent. The reported incidence of PNI fluctuates from 4.73% to 24.7% d…
View article: Compound motor action potentials in transient and persistent phrenic nerve injury - metanalysis.
Compound motor action potentials in transient and persistent phrenic nerve injury - metanalysis. Open
Background: The right phrenic nerve is vulnerable to injury (rPNI) during cryoballoon ablation (CBA) isolation of the right pulmonary veins. The complication can be transient or persistent. The reported incidence of rPNI fluctuates from 4.…
View article: How to write an umbrella review? A step-by-step tutorial with tips and tricks
How to write an umbrella review? A step-by-step tutorial with tips and tricks Open
The number of meta-analyses (MA) and systematic reviews (SR) on various medical issues has increased during the last two decades. The MA and SR results may differ from one another due to a number of factors such as inaccurate or diverse se…
View article: Topographical anatomy of the left ventricular summit: implications for invasive procedures
Topographical anatomy of the left ventricular summit: implications for invasive procedures Open
The difference in size and content of the LVS is significant, with no correlation to any variable. The size depends on the anatomy of the most prominent septal perforator artery. The superior, inaccessible aspect dominates, and the LVS is …
View article: Anatomical and electrophysiological localization of ganglionated plexi using high-density 3D CARTO mapping system
Anatomical and electrophysiological localization of ganglionated plexi using high-density 3D CARTO mapping system Open
Background: The autonomic nervous system can be visualized with a 3D map created in the CARTO® 3 system. This advanced imaging technology utilizes electromagnetic technology to create real-time three-dimensional (3D) maps of a patient's ca…
View article: Prevalence of Arrhythmia in Adults after Fontan Operation
Prevalence of Arrhythmia in Adults after Fontan Operation Open
Structural, hemodynamic, and morphological cardiac changes following Fontan operation (FO) can contribute to the development of arrhythmias and conduction disorders. Sinus node dysfunction, junction rhythms, tachyarrhythmias, and ventricul…
View article: Novel micro-computed tomography contrast agents to visualise the human cardiac conduction system and surrounding structures in hearts from normal, aged, and obese individuals
Novel micro-computed tomography contrast agents to visualise the human cardiac conduction system and surrounding structures in hearts from normal, aged, and obese individuals Open
Research purpose: The cardiac conduction system (CCS) regulates electrical impulses across the heart and cardiac arrhythmias cause structural remodelling of the CCS. Since its discovery over a century ago, the precise anatomy and differenc…
View article: Contact Force-Sensing versus Standard Catheters in Non-Fluoroscopic Radiofrequency Catheter Ablation of Idiopathic Outflow Tract Ventricular Arrhythmias
Contact Force-Sensing versus Standard Catheters in Non-Fluoroscopic Radiofrequency Catheter Ablation of Idiopathic Outflow Tract Ventricular Arrhythmias Open
Background: Adequate contact between the catheter tip and tissue is important for optimal lesion formation and, in some procedures, it has been associated with improved effectiveness and safety. We evaluated the potential benefits of conta…
View article: Left Ventricular Summit—Concept, Anatomical Structure and Clinical Significance
Left Ventricular Summit—Concept, Anatomical Structure and Clinical Significance Open
The left ventricular summit (LVS) is a triangular area located at the most superior portion of the left epicardial ventricular region, surrounded by the two branches of the left coronary artery: the left anterior interventricular artery an…