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View article: Development and validation of an LC-HRMS method for the determination of monomers of wine fining PVPP and PVI-PVP polymers
Development and validation of an LC-HRMS method for the determination of monomers of wine fining PVPP and PVI-PVP polymers Open
A HPLC-HRMS method was developed and validated to analyze the polyvinylimidazole/polyvinylpyrrolidone (PVI/PVP) monomers (N-vinylimidazole, N-vinyl-2-pyrrolidone, imidazole, and 2-pyrrolidone) in wines. The use of a C30 column and HRMS all…
View article: Effect of Mild Conditions on PVA-Based Theta Gel Preparation: Thermal and Rheological Characterization
Effect of Mild Conditions on PVA-Based Theta Gel Preparation: Thermal and Rheological Characterization Open
Polyvinyl alcohol (PVA), possessing a strong ability to form hydrogels, has been widely used for various pharmaceutical and biomedical applications. In particular, the use of PVA-PEG in the form of theta gels for altered cartilage treatmen…
View article: Determination of Elemental Content in Vineyard Soil, Leaves, and Grapes of Sangiovese Grapes from the Chianti Region Using ICP-MS for Geographical Identification
Determination of Elemental Content in Vineyard Soil, Leaves, and Grapes of Sangiovese Grapes from the Chianti Region Using ICP-MS for Geographical Identification Open
To fight counterfeits and to protect the consumer, the interest in certifying the origin of agricultural goods has been steadily growing in the last years. While numerous works focus on the finished product, an aspect often overlooked is t…
View article: Effect of Annurca Apple Extract on Anti-hyper Cholesterol Action of a RYR based Formulation
Effect of Annurca Apple Extract on Anti-hyper Cholesterol Action of a RYR based Formulation Open
Recently, European Authorities imposed that any product for daily consumption shall provide less than 3 mg of monacolins from red yeast rice (RYR). This obliges to find new formulations able to guarantee an effect on cholesterol levels clo…
View article: Liposomal Encapsulation of Citicoline for Ocular Drug Delivery
Liposomal Encapsulation of Citicoline for Ocular Drug Delivery Open
Glaucoma represents a group of neurodegenerative diseases characterized by optic nerve damage and the slowly progressive death of retinal ganglion cells. Glaucoma is considered the second leading cause of irreversible blindness worldwide. …
View article: Design and Optimization of Solid Lipid Nanoparticles Loaded with Triamcinolone Acetonide
Design and Optimization of Solid Lipid Nanoparticles Loaded with Triamcinolone Acetonide Open
Principles of quality by design and design of experiments are acquiring more importance in the discovery and application of new drug carriers, such as solid lipid nanoparticles. In this work, an optimized synthesis of solid lipid nanoparti…
View article: Characterization of Extracts of Coffee Leaves (Coffea arabica L.) by Spectroscopic and Chromatographic/Spectrometric Techniques
Characterization of Extracts of Coffee Leaves (Coffea arabica L.) by Spectroscopic and Chromatographic/Spectrometric Techniques Open
Coffea arabica L. leaves represent a viable alternative to the canonical matrices used for preparation of beverages, such as tea leaves and grounded coffee beans. Coffee leaves infusions are rich in antioxidant phenolic compounds and have …
View article: Bioactive Compounds and Their Impact on Protein Modification in Human Cells
Bioactive Compounds and Their Impact on Protein Modification in Human Cells Open
Reactive oxygen species (ROS) represent a group of molecules with a signaling role that are involved in regulating human cell proliferation and differentiation. Increased ROS concentrations are often associated with the local nonspecific o…
View article: Effect of Flaking and Precooking Procedures on Antioxidant Potential of Selected Ancient Cereal and Legume Flours
Effect of Flaking and Precooking Procedures on Antioxidant Potential of Selected Ancient Cereal and Legume Flours Open
Consumption of cereals (and particularly ancient cereals) is considered the base of a healthy diet, and all current dietary guidelines have cereals at the bottom of the nutrition pyramid. Together with cereals, legumes are an excellent sou…
View article: Physicochemical Characterization of Hyaluronic Acid and Chitosan Liposome Coatings
Physicochemical Characterization of Hyaluronic Acid and Chitosan Liposome Coatings Open
Hyaluronic acid (HA) and chitosan (CH) are biopolymers that are widely used in many biomedical applications and for cosmetic purposes. Their chemical properties are fundamental to them working as drug delivery systems and improving their s…
View article: Varietal and Geographical Origin Characterization of Peaches and Nectarines by Combining Analytical Techniques and Statistical Approach
Varietal and Geographical Origin Characterization of Peaches and Nectarines by Combining Analytical Techniques and Statistical Approach Open
Prunus persica L. is one of the most important fruit crops in European production, after grapes, apples, oranges and watermelons. Most varieties are rich in secondary metabolites, showing antioxidant properties for human health. The purpos…
View article: Combined Experimental and Multivariate Model Approaches for Glycoalkaloid Quantification in Tomatoes
Combined Experimental and Multivariate Model Approaches for Glycoalkaloid Quantification in Tomatoes Open
The intake of tomato glycoalkaloids can exert beneficial effects on human health. For this reason, methods for a rapid quantification of these compounds are required. Most of the methods for α-tomatine and dehydrotomatine quantification ar…
View article: Solid Lipid Nanoparticles Produced via a Coacervation Method as Promising Carriers for Controlled Release of Quercetin
Solid Lipid Nanoparticles Produced via a Coacervation Method as Promising Carriers for Controlled Release of Quercetin Open
Quercetin is a poorly water-soluble flavonoid with many benefits to human health. Besides the natural food resources that may provide Quercetin, the interest in delivery systems that could enhance its bioavailability in the human body has …
View article: Microplastics Contamination versus Inorganic Particles: Effects on the Dynamics of Marine Dissolved Organic Matter
Microplastics Contamination versus Inorganic Particles: Effects on the Dynamics of Marine Dissolved Organic Matter Open
Microplastic contamination has been linked to a range of impacts on aquatic environments. One important area that is only beginning to be addressed is the effect of microplastics on marine carbon cycling and how these compare to the effect…
View article: Non-Destructive Monitoring of P. fluorescens and S. epidermidis Biofilm under Different Media by Fourier Transform Infrared Spectroscopy and Other Corroborative Techniques
Non-Destructive Monitoring of P. fluorescens and S. epidermidis Biofilm under Different Media by Fourier Transform Infrared Spectroscopy and Other Corroborative Techniques Open
In the present study, the early stage of bacteria biofilm formation has been studied as a function of different nutrients. Infrared spectra of Pseudomonas fluorescens (PF) and Staphylococcus epidermidis (SE), on germanium ATR crystal, were…
View article: Chemical/Instrumental Approaches to the Evaluation of Wine Chemistry
Chemical/Instrumental Approaches to the Evaluation of Wine Chemistry Open
Wine is a widely consumed beverage due to its unique and pleasant sensory properties. Wine is composed of more than one thousand chemical compounds (e.g., alcohols, esters, acids, terpenoids, phenolic compounds, flavonoids, anthocyanins, m…
View article: Chemical characterization and antioxidant properties of products and by‐products from <i>Olea europaea</i> L.
Chemical characterization and antioxidant properties of products and by‐products from <i>Olea europaea</i> L. Open
The products and by‐products of Olea europaea L.: olive fruits (primary agricultural product), oils (primary agro‐industrial product), pomaces (agro‐industrial processing by‐product), and leaves (agricultural practices by‐product), are pro…
View article: Metal-Ligand Recognition Index Determination by NMR Proton Relaxation Study
Metal-Ligand Recognition Index Determination by NMR Proton Relaxation Study Open
In this study, we developed and validated a new proposed parameter quantifying the interaction strength between natural and/or synthetic molecules with paramagnetic metal ions. The Metal ion Recognition Index, Miri, is a quantitative param…
View article: Distribution of Gadolinium in Rat Heart Studied by Fast Field Cycling Relaxometry and Imaging SIMS
Distribution of Gadolinium in Rat Heart Studied by Fast Field Cycling Relaxometry and Imaging SIMS Open
Research on microcirculatory alterations in human heart disease is essential to understand the genesis of myocardial contractile dysfunction and its evolution towards heart failure. The use of contrast agents in magnetic resonance imaging …
View article: Antioxidant Species in Grapes and Wines via Spectrophotometric Methods: No Quenching Effects by Copper(II) and Yeast Derivative Treatments
Antioxidant Species in Grapes and Wines via Spectrophotometric Methods: No Quenching Effects by Copper(II) and Yeast Derivative Treatments Open
Analytical determinations for selected parameters in grapes/wines help planning technology treatments in the vineyards and cellars, improving the quality of final products and preserving consumers’ health. The study first reports a compara…
View article: Ionic Exchange Resins and Hydrogels for Capturing Metal Ions in Selected Sweet Dessert Wines
Ionic Exchange Resins and Hydrogels for Capturing Metal Ions in Selected Sweet Dessert Wines Open
Samples of sweet and dessert wines, Vin Santo (VSR) from Malvasia grapes, and Granello (GR) from Sauvignon grapes were collected and analyzed for the content of selected macro- and micro-nutrients (Na, K, Mg, Ca, Mn, Fe, Cu and Zn) and of …
View article: Homogentisic acid induces morphological and mechanical aberration of ochronotic cartilage in alkaptonuria
Homogentisic acid induces morphological and mechanical aberration of ochronotic cartilage in alkaptonuria Open
Alkaptonuria (AKU) is a disease caused by a deficient homogentisate 1,2‐dioxygenase activity leading to systemic accumulation of homogentisic acid (HGA), that forms a melanin‐like polymer that progressively deposits onto connective tissues…