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View article: Hematopoietic stem cell transplantation disrupts age-related gut microbiota signatures in pediatric and adult recipients
Hematopoietic stem cell transplantation disrupts age-related gut microbiota signatures in pediatric and adult recipients Open
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) profoundly reshapes the gut microbiome (GM), yet age-related differences in this process remain incompletely understood. In this study, we analyzed stool samples from a cohort …
View article: Microbiome-based prediction of allogeneic hematopoietic stem cell transplantation outcome
Microbiome-based prediction of allogeneic hematopoietic stem cell transplantation outcome Open
Microbiome profiling of stool and saliva samples offers robust, time-sensitive prediction of post-HSCT complications. The RATIO model enables interpretable, time-to-event prediction across multiple outcomes and may inform microbiome-guided…
View article: 408 | INTEGRATIVE PROFILING OF GUT MICROBIOME AND FDG‐PET PARAMETERS AS PREDICTORS OF CAR T‐CELL THERAPY OUTCOMES IN RELAPSED/REFRACTORY DIFFUSE LARGE B‐CELL LYMPHOMAS
408 | INTEGRATIVE PROFILING OF GUT MICROBIOME AND FDG‐PET PARAMETERS AS PREDICTORS OF CAR T‐CELL THERAPY OUTCOMES IN RELAPSED/REFRACTORY DIFFUSE LARGE B‐CELL LYMPHOMAS Open
View article: Consumption of only wild foods induces large scale, partially persistent alterations to the gut microbiome
Consumption of only wild foods induces large scale, partially persistent alterations to the gut microbiome Open
The gut microbiome (GM) is implicated in human health and varies among lifestyles. So-called "traditional" diets have been suggested to promote health-associated taxa. However, most studies focused only on diets including domesticated food…
View article: Levofloxacin Prophylaxis in Pediatric and Young Adult Allogeneic Hematopoietic Stem Cell Transplantation Recipients Does not Prevent Infective Complications and Infections-related Deaths
Levofloxacin Prophylaxis in Pediatric and Young Adult Allogeneic Hematopoietic Stem Cell Transplantation Recipients Does not Prevent Infective Complications and Infections-related Deaths Open
Background The prophylactic use of quinolones in the setting of allogeneic hematopoietic stem cell transplantation (allo-HCT) is controversial and solid evidence is missing, particularly in children. Methods In this single-center retrospec…
View article: The gut microbiota as an early predictor of COVID-19 severity
The gut microbiota as an early predictor of COVID-19 severity Open
Several studies reported alterations of the human gut microbiota (GM) during COVID-19. To evaluate the potential role of the GM as an early predictor of COVID-19 at disease onset, we analyzed gut microbial samples of 315 COVID-19 patients …
View article: Early and late gut microbiota signatures of stroke in high salt-fed stroke-prone spontaneously hypertensive rats
Early and late gut microbiota signatures of stroke in high salt-fed stroke-prone spontaneously hypertensive rats Open
View article: Gut microbiome dynamics and Enterobacterales infection in liver transplant recipients: A prospective observational study
Gut microbiome dynamics and Enterobacterales infection in liver transplant recipients: A prospective observational study Open
View article: The gut microbiome of Baka forager-horticulturalists from Cameroon is optimized for wild plant foods
The gut microbiome of Baka forager-horticulturalists from Cameroon is optimized for wild plant foods Open
The human gut microbiome is losing biodiversity, due to the "microbiome modernization process" that occurs with urbanization. To keep track of it, here we applied shotgun metagenomics to the gut microbiome of the Baka, a group of forager-h…
View article: Consumption of only wild foods induces large-scale, partially-persistent alterations to the gut microbiome
Consumption of only wild foods induces large-scale, partially-persistent alterations to the gut microbiome Open
The composition of the gut microbiome (GM) affects human health and varies among lifestyles. Adopting more “traditional” diets could lead to substantive and health-associated changes in the GM. However, research has focused on diets includ…
View article: A personalized diet intervention improves depression symptoms and changes microbiota and metabolite profiles among community-dwelling older adults
A personalized diet intervention improves depression symptoms and changes microbiota and metabolite profiles among community-dwelling older adults Open
Introduction The impact of diet on mental well-being and gut microorganisms in humans is well recognized. However, research on the connections between food nutrients, gut microbiota, and mental health remains limited. To address this, the …
View article: Microbiota-gut-brain axis and ketogenic diet: how close are we to tackling epilepsy?
Microbiota-gut-brain axis and ketogenic diet: how close are we to tackling epilepsy? Open
The microbiota-gut-brain axis refers to the intricate bidirectional communication between commensal microorganisms residing in the digestive tract and the central nervous system, along neuroendocrine, metabolic, immune, and inflammatory pa…
View article: Gut, oral, and nasopharyngeal microbiota dynamics in the clinical course of hospitalized infants with respiratory syncytial virus bronchiolitis
Gut, oral, and nasopharyngeal microbiota dynamics in the clinical course of hospitalized infants with respiratory syncytial virus bronchiolitis Open
Introduction Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis and hospitalization in infants worldwide. The nasopharyngeal microbiota has been suggested to play a role in influencing the clinical course of RSV br…
View article: A comparative absorption study of sucrosomial® orodispersible vitamin D3 supplementation vs. a reference chewable tablet and soft gel capsule vitamin D3 in improving circulatory 25(OH)D levels in healthy adults with vitamin D deficiency—Results from a prospective randomized clinical trial
A comparative absorption study of sucrosomial® orodispersible vitamin D3 supplementation vs. a reference chewable tablet and soft gel capsule vitamin D3 in improving circulatory 25(OH)D levels in healthy adults with vitamin D deficiency—Results from a prospective randomized clinical trial Open
Background Vitamin D (Vit D) deficiency (VDD), associated with diverse health conditions, is commonly treated with Vit D3 supplements. However, the gastrointestinal (GI) absorption of Vit D3 in different formulations has not been well stud…
View article: Gut microbiota diversity before allogeneic hematopoietic stem cell transplantation as a predictor of mortality in children
Gut microbiota diversity before allogeneic hematopoietic stem cell transplantation as a predictor of mortality in children Open
The correlation existing between gut microbiota diversity and survival after allogeneic hematopoietic stem cell transplantation (allo-HSCT) has so far been studied in adults. Pediatric studies question whether this association applies to c…
View article: Connect the dots: sketching out microbiome interactions through networking approaches
Connect the dots: sketching out microbiome interactions through networking approaches Open
Microbiome networking analysis has emerged as a powerful tool for studying the complex interactions among microorganisms in various ecological niches, including the human body and several environments. This analysis has been used extensive…
View article: Gut Microbiota, Metabolome, and Body Composition Signatures of Response to Therapy in Patients with Advanced Melanoma
Gut Microbiota, Metabolome, and Body Composition Signatures of Response to Therapy in Patients with Advanced Melanoma Open
Despite the recent breakthroughs in targeted and immunotherapy for melanoma, the overall survival rate remains low. In recent years, considerable attention has been paid to the gut microbiota and other modifiable patient factors (e.g., die…
View article: Composition and biodiversity of soil and root-associated microbiome in Vitis vinifera cultivar Lambrusco distinguish the microbial terroir of the Lambrusco DOC protected designation of origin area on a local scale
Composition and biodiversity of soil and root-associated microbiome in Vitis vinifera cultivar Lambrusco distinguish the microbial terroir of the Lambrusco DOC protected designation of origin area on a local scale Open
Introduction Wines produced from the same grape cultivars but in different locations possess distinctive qualities leading to different consumer’s appreciation, preferences, and thus purchase choices. Here, we explore the possible importan…
View article: Levofloxacin prophylaxis and parenteral nutrition have a detrimental effect on intestinal microbial networks in pediatric patients undergoing HSCT
Levofloxacin prophylaxis and parenteral nutrition have a detrimental effect on intestinal microbial networks in pediatric patients undergoing HSCT Open
View article: The Gut Microbiome of Baka Forager-Horticulturalists from Southeastern Cameroon is Optimized for Metabolizing Wild Plant Foods
The Gut Microbiome of Baka Forager-Horticulturalists from Southeastern Cameroon is Optimized for Metabolizing Wild Plant Foods Open
View article: Gut microbiota resilience and recovery after anticancer chemotherapy
Gut microbiota resilience and recovery after anticancer chemotherapy Open
Although research on the role of the gut microbiota (GM) in human health has sharply increased in recent years, what a “healthy” gut microbiota is and how it responds to major stressors is still difficult to establish. In particular, antic…
View article: Pharmacomicrobiomics in Anticancer Therapies: Why the Gut Microbiota Should Be Pointed Out
Pharmacomicrobiomics in Anticancer Therapies: Why the Gut Microbiota Should Be Pointed Out Open
Anticancer treatments have shown a variable therapeutic outcome that may be partly attributable to the activity of the gut microbiota on the pathology and/or therapies. In recent years, microbiota–drug interactions have been extensively in…
View article: Make It Less difficile: Understanding Genetic Evolution and Global Spread of Clostridioides difficile
Make It Less difficile: Understanding Genetic Evolution and Global Spread of Clostridioides difficile Open
Clostridioides difficile is an obligate anaerobic pathogen among the most common causes of healthcare-associated infections. It poses a global threat due to the clinical outcomes of infection and resistance to antibiotics recommended by in…
View article: Exploring clade differentiation of the Faecalibacterium prausnitzii complex
Exploring clade differentiation of the Faecalibacterium prausnitzii complex Open
Faecalibacterium prausnitzii is one of the most prevalent and abundant polyphyletic health-promoting components of the human gut microbiome with a propensity for dysbiotic decreases. To better understand its biology in the human gut…
View article: Microbiome network in the pelagic and benthic offshore systems of the northern Adriatic Sea (Mediterranean Sea)
Microbiome network in the pelagic and benthic offshore systems of the northern Adriatic Sea (Mediterranean Sea) Open
View article: Microbiome network in the pelagic and benthic offshore systems of the northern Adriatic Sea (Mediterranean Sea)
Microbiome network in the pelagic and benthic offshore systems of the northern Adriatic Sea (Mediterranean Sea) Open
Background Because of their recognized global importance, there is now the urgent need to map diversity and distribution patterns of marine microbial communities. Even if available studies provided some advances in the understanding the bi…
View article: The Core Human Microbiome: Does It Exist and How Can We Find It? A Critical Review of the Concept
The Core Human Microbiome: Does It Exist and How Can We Find It? A Critical Review of the Concept Open
The core microbiome, which refers to a set of consistent microbial features across populations, is of major interest in microbiome research and has been addressed by numerous studies. Understanding the core microbiome can help identify ele…
View article: Polyphenol and Tannin Nutraceuticals and Their Metabolites: How the Human Gut Microbiota Influences Their Properties
Polyphenol and Tannin Nutraceuticals and Their Metabolites: How the Human Gut Microbiota Influences Their Properties Open
Nutraceuticals have been receiving increasing attention in the last few years due to their potential role as adjuvants against non-communicable chronic diseases (cardiovascular disease, diabetes, cancer, etc.). However, a limited number of…
View article: Microbiome network in the pelagic and benthic offshore systems of the northern Adriatic Sea (Mediterranean Sea)
Microbiome network in the pelagic and benthic offshore systems of the northern Adriatic Sea (Mediterranean Sea) Open
Background Because of their recognized global importance, there is now the urgent need to map diversity and distribution patterns of marine microbial communities. Even if available studies provided some advances in the understanding the bi…
View article: Figure 4 - Metabolic potential
Figure 4 - Metabolic potential Open
Metabolic potential for the degradation of amino acid, carbohydrates, lipids and xenobiotics in HSCT patients