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View article: Isolation and Characterization of Articular Cartilage-Derived Cells Obtained by Arthroscopic Cartilage Biopsy from Non-Osteoarthritic Patients
Isolation and Characterization of Articular Cartilage-Derived Cells Obtained by Arthroscopic Cartilage Biopsy from Non-Osteoarthritic Patients Open
Cartilage-derived migratory cells show great potential for autologous use in cartilage repair surgery. However, their collection through arthroscopic biopsy has not been previously reported in individuals without osteoarthritis. This study…
View article: TNF-Alpha Inhibitor Prevents Cigarette Smoke Extract-Induced Cell Death in Osteoarthritis-Derived Chondrocytes in Culture
TNF-Alpha Inhibitor Prevents Cigarette Smoke Extract-Induced Cell Death in Osteoarthritis-Derived Chondrocytes in Culture Open
Smoking has been associated, among other factors, with musculoskeletal disorders. Although there is no consensus about the effects of smoking on osteoarthritis (OA), the increase in TNF-alpha in smokers has been considered an important fac…
View article: MICRO-FRAGMENTED ADIPOSE TISSUE IN THE KNEE OSTEOARTHRITIS UNDER LOCAL ANESTHESIA
MICRO-FRAGMENTED ADIPOSE TISSUE IN THE KNEE OSTEOARTHRITIS UNDER LOCAL ANESTHESIA Open
Objective: To assess the feasibility of the entire micro fragmented adipose tissue knee injection procedure under local anesthesia. From the subcutaneous harvesting and microfragmentation process to the intrarticular knee injection. Method…
View article: Influence of Human Bone Marrow Mesenchymal Stem Cells Secretome from Acute Myeloid Leukemia Patients on the Proliferation and Death of K562 and K562-Lucena Leukemia Cell Lineages
Influence of Human Bone Marrow Mesenchymal Stem Cells Secretome from Acute Myeloid Leukemia Patients on the Proliferation and Death of K562 and K562-Lucena Leukemia Cell Lineages Open
Leukemias are among the most prevalent types of cancer worldwide. Bone marrow mesenchymal stem cells (MSCs) participate in the development of a suitable niche for hematopoietic stem cells, and are involved in the development of diseases su…
View article: Hyperbaric oxygen therapy enhances graft healing and mechanical properties after anterior cruciate ligament reconstruction: An experimental study in rabbits
Hyperbaric oxygen therapy enhances graft healing and mechanical properties after anterior cruciate ligament reconstruction: An experimental study in rabbits Open
Hyperbaric oxygen therapy (HBOT) has proven successful in wound healing. However, its potential effects on anterior cruciate ligament (ACL) injuries remain uncertain. This study aimed to investigate the impact of HBOT on graft healing foll…
View article: Quantitative alpha-defensin testing: Is synovial fluid dilution important?
Quantitative alpha-defensin testing: Is synovial fluid dilution important? Open
The synovial fluid dilution had an important influence on the alpha-defensin ELISA results. Dilutions of 1:5000 showed the best performance for the diagnosis of knee PJI. The results of this study set the basis for a more reliable and repr…
View article: Use of small animal PET-CT imaging for <i>in vivo</i> assessment of tendon-to-bone healing: A pilot study
Use of small animal PET-CT imaging for <i>in vivo</i> assessment of tendon-to-bone healing: A pilot study Open
Background The availability of non-invasive means to evaluate and monitor tendon-bone healing processes in-vivo is limited. Micro Positron-Emission-Tomography (µPET) using 18 F-Fluoride is a minimally invasive imaging modality, with which …
View article: EXTENSOR MECHANISM TRANSPLANTATION AFTER KNEE PROSTHESIS: 70-MONTH FOLLOW-UP
EXTENSOR MECHANISM TRANSPLANTATION AFTER KNEE PROSTHESIS: 70-MONTH FOLLOW-UP Open
Objective: This article reports the range of motion, failure rate, and complications of patients with extensor mechanism injury after total knee arthroplasty (TKA) treated with extensor mechanism allograft with mid-term follow-up. Methods:…
View article: Performance of alpha-defensin lateral flow test after synovial fluid centrifugation for diagnosis of periprosthetic knee infection
Performance of alpha-defensin lateral flow test after synovial fluid centrifugation for diagnosis of periprosthetic knee infection Open
Alpha-defensin lateral flow test showed high SE, SP and accuracy after a prior synovial fluid centrifugation, achieving comparable results to ELISA. Considering the lower complexity of the lateral flow and its equivalent performance obtain…
View article: LEVER SIGN TEST FOR CHRONIC ACL INJURY: A COMPARISON WITH LACHMAN AND ANTERIOR DRAWER TESTS
LEVER SIGN TEST FOR CHRONIC ACL INJURY: A COMPARISON WITH LACHMAN AND ANTERIOR DRAWER TESTS Open
Objective: This study aims to evaluate the sensitivity and specificity of the lever sign test in patients with and without chronic Anterior Cruciate Ligament (ACL) injuries in an outpatient setting and the inter-examiner agreement of surge…
View article: AUTOLOGOUS CHONDROCYTE IMPLANTATION IN BRAZIL
AUTOLOGOUS CHONDROCYTE IMPLANTATION IN BRAZIL Open
Objective: To describe the first series of cases of autologous chondrocyte implantation (ACI) in collagen membrane performed in Brazil. Methods: ACI was performed in 12 knees of 11 patients, aged 32.1 ± 10.9 years, with 5.3 ± 2.6 cm2 full-…
View article: Diagnostic Accuracy of Comparative Computed Tomography with Stress Maneuvers for Diagnosing Isolated Syndesmotic Instability in an Acute Ankle Sprain
Diagnostic Accuracy of Comparative Computed Tomography with Stress Maneuvers for Diagnosing Isolated Syndesmotic Instability in an Acute Ankle Sprain Open
Category: Ankle; Sports; Trauma Introduction/Purpose: Although there are several imaging options for diagnosing the syndesmotic injury, a fundamental question that guides treatment remains unanswered. Syndesmotic instability is still chall…
View article: Treatment of subchondral insufficiency fracture of the knee by subchondroplasty
Treatment of subchondral insufficiency fracture of the knee by subchondroplasty Open
Background: Subchondral insufficiency fracture greatly impacts the quality of life of patients, causes much pain, and has the potential to rapidly progress to degeneration of the knee. Application of a calcium phosphate bone graft to the s…
View article: Comparative CT with stress manoeuvres for diagnosing distal isolated tibiofibular syndesmotic injury in acute ankle sprain: a protocol for an accuracy- test prospective study
Comparative CT with stress manoeuvres for diagnosing distal isolated tibiofibular syndesmotic injury in acute ankle sprain: a protocol for an accuracy- test prospective study Open
Introduction Although several imaging options are available for diagnosing syndesmotic injury, a fundamental question that guides treatment remains unanswered. Syndesmotic instability is still challenging to diagnose correctly, and syndesm…
View article: The use of negative-pressure wound therapy after total knee arthroplasty is effective for reducing complications and the need for reintervention.
The use of negative-pressure wound therapy after total knee arthroplasty is effective for reducing complications and the need for reintervention. Open
Background: Wound healing complications are causal factors of prosthesis infection and poor postoperative evolution of patients after total knee arthroplasty (TKA). Negative-pressure wound therapy (NPWT) can be an option to minimize these …
View article: AUTOLOGOUS CHONDROCYTE IMPLANTATION IN BRAZIL
AUTOLOGOUS CHONDROCYTE IMPLANTATION IN BRAZIL Open
Objective: To describe the first series of cases of autologous chondrocyte implantation (ACI) in collagen membrane performed in Brazil. Methods: ACI was performed in 12 knees of 11 patients, aged 32.1 ± 10.9 years, with 5.3 ± 2.6 cm2 full-…
View article: The use of negative-pressure wound therapy after total knee arthroplasty is effective for reducing complications and the need for reintervention.
The use of negative-pressure wound therapy after total knee arthroplasty is effective for reducing complications and the need for reintervention. Open
Background: Compare the complications of patients undergoing total knee arthroplasty (TKA) who used a portable negative-pressure wound therapy (NPWT) device in the immediate postoperative period with those of a control group. Methods: A to…
View article: ASSESSMENT OF THE USE OF TRANEXAMIC ACID AFTER TOTAL KNEE ARTHROPLASTY
ASSESSMENT OF THE USE OF TRANEXAMIC ACID AFTER TOTAL KNEE ARTHROPLASTY Open
Objective: To evaluate the profile of blood loss and blood transfusions after the introduction of Tranexamic acid (TXA) in a tertiary university hospital in Brazil. Methods: 173 patients were retrospectively divided into two groups: the on…
View article: Comparative Computed Tomography with Stress Manoeuvres for Diagnosing Distal Isolated Tibiofibular Syndesmotic Injury in Acute Ankle Sprain: a Protocol for an Accuracy-Test Prospective Study
Comparative Computed Tomography with Stress Manoeuvres for Diagnosing Distal Isolated Tibiofibular Syndesmotic Injury in Acute Ankle Sprain: a Protocol for an Accuracy-Test Prospective Study Open
Introduction Although there are several imaging options for diagnosing syndesmotic injury, a fundamental question that guides treatment remains unanswered. Syndesmotic instability is still challenging to correctly diagnose, and syndesmotic…
View article: The Vastus Medialis Insertion Is More Proximal and Medial in Patients With Patellar Instability: A Magnetic Resonance Imaging Case-Control Study
The Vastus Medialis Insertion Is More Proximal and Medial in Patients With Patellar Instability: A Magnetic Resonance Imaging Case-Control Study Open
Background: The anatomy and function of the quadriceps muscle play a role in patellofemoral stability. Few studies have evaluated anatomic differences in the vastus medialis between patients with and without patellar instability. Purpose: …
View article: BIOLOGICAL ENHANCEMENTS FOR ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
BIOLOGICAL ENHANCEMENTS FOR ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION Open
The anterior cruciate ligament (ACL) is mostly responsible for providing knee stability. ACL injury has a marked effect on daily activities, causing pain, dysfunction, and elevated healthcare costs. ACL reconstruction (ACLR) is the standar…
View article: REVIEW OF TOTAL KNEE ARTHROPLASTY AND THE BRAZILIAN UNIFIED HEALTH SYSTEM: A NATIONAL PROBLEM
REVIEW OF TOTAL KNEE ARTHROPLASTY AND THE BRAZILIAN UNIFIED HEALTH SYSTEM: A NATIONAL PROBLEM Open
Objectives: To analyze, through DATASUS data, the historical trend of revision of total knee arthroplasty (TKA) in the period between 2008-2016 and to relate them to demographic, regional and national aspects. Methods: Elaboration of a his…
View article: EXTRA-ARTICULAR RECONSTRUCTION ASSOCIATED WITH THE ANTERIOR CRUCIATE LIGAMENT IN BRAZIL
EXTRA-ARTICULAR RECONSTRUCTION ASSOCIATED WITH THE ANTERIOR CRUCIATE LIGAMENT IN BRAZIL Open
Objective: To assess the knowledge and technical preferences of Brazilian knee surgeons in relation to the treatment of Anterior Cruciate Ligament (ACL) injuries using intra-articular reconstruction in combination with extra-articular reco…