Marco N. Helder
YOU?
Author Swipe
View article: Neodymium-doped mesoporous silica nanoparticles promote bone regeneration via autophagy-mediated macrophage immunomodulation
Neodymium-doped mesoporous silica nanoparticles promote bone regeneration via autophagy-mediated macrophage immunomodulation Open
View article: Pollen-like mesoporous silica nanoparticles facilitate macrophage-mediated anti-inflammatory response via physical contact cues in the osteoimmune microenvironment
Pollen-like mesoporous silica nanoparticles facilitate macrophage-mediated anti-inflammatory response via physical contact cues in the osteoimmune microenvironment Open
View article: Psychological and quality of life outcomes following orthognathic surgery: A comprehensive systematic review
Psychological and quality of life outcomes following orthognathic surgery: A comprehensive systematic review Open
View article: The Effectiveness of Nanofat in the Management of Skin Scars: A Systematic Review
The Effectiveness of Nanofat in the Management of Skin Scars: A Systematic Review Open
Nanofat is an adipose tissue product obtained through mechanical emulsification, preserving stromal vascular fraction and extracellular matrix. Nanofat has been primarily investigated in the contexts of skin scar repair. This systematic re…
View article: Sociodemographic Influence on the Management of Orofacial Cleft in Urban and Rural Indonesia
Sociodemographic Influence on the Management of Orofacial Cleft in Urban and Rural Indonesia Open
Objective To explore the social experiences of orofacial cleft patients and contextualize sociodemographic influence on management disparities in rural and urban areas of Indonesia. Design This study explores patients’ lives in two demogra…
View article: A systematic review and meta-analysis on the use of regenerative graft materials for socket preservation in randomized clinical trials
A systematic review and meta-analysis on the use of regenerative graft materials for socket preservation in randomized clinical trials Open
View article: The osteogenic potential of seaweed: A systematic review and meta-analysis
The osteogenic potential of seaweed: A systematic review and meta-analysis Open
Recently seaweeds have gained intense interest as a source for developing seaweed compound-based therapies for bone growth. While several seaweed compounds were tested in pre-clinical models, an overview article of their osteogenic potenti…
View article: Microfragmented Fat and Biphasic Calcium Phosphates for Alveolar Cleft Repair: Protocol for a Prospective, Nonblinded, First-in-Human Clinical Study
Microfragmented Fat and Biphasic Calcium Phosphates for Alveolar Cleft Repair: Protocol for a Prospective, Nonblinded, First-in-Human Clinical Study Open
Background Biphasic calcium phosphates (BCP) may serve as off-the-shelf alternatives for iliac crest-derived autologous bone in alveolar cleft reconstructions. To add osteoinductivity to the osteoconductive BCPs to achieve similar regenera…
View article: Cultural Beliefs on Cleft lip and/or Cleft Palate and Their Implications on Management: A Systematic Review
Cultural Beliefs on Cleft lip and/or Cleft Palate and Their Implications on Management: A Systematic Review Open
Objective This article examines and summarizes the published epidemiological literature on cross-cultural variations. Particular emphasis was put on addressing cross-cultural beliefs on the causes, management, and attitude toward cleft lip…
View article: Long-Term Safety of Bone Regeneration Using Autologous Stromal Vascular Fraction and Calcium Phosphate Ceramics: A 10-Year Prospective Cohort Study
Long-Term Safety of Bone Regeneration Using Autologous Stromal Vascular Fraction and Calcium Phosphate Ceramics: A 10-Year Prospective Cohort Study Open
This prospective cohort study aimed to assess long-term safety, dental implant survival, and clinical and radiological outcomes after maxillary sinus floor elevation (MSFE; lateral window technique) using freshly isolated autologous stroma…
View article: Intraoperative Visualization and Treatment of Salivary Gland Dysfunction in Sjögren’s Syndrome Patients Using Contrast-Enhanced Ultrasound Sialendoscopy (CEUSS)
Intraoperative Visualization and Treatment of Salivary Gland Dysfunction in Sjögren’s Syndrome Patients Using Contrast-Enhanced Ultrasound Sialendoscopy (CEUSS) Open
In sialendoscopy, ducts are dilated and the salivary glands are irrigated with saline. Contrast-enhanced ultrasound sialendoscopy (CEUSS), using microbubbles, may facilitate the monitoring of irrigation solution penetration in the ductal s…
View article: A narrative review of the role of Eph receptors in head and neck squamous cell carcinoma
A narrative review of the role of Eph receptors in head and neck squamous cell carcinoma Open
Tyrosine kinase receptors (TKR) coordinate a variety of pathological processes in head and neck squamous cell carcinoma (HNSCC), and eventually play a role in patient outcomes. In this review, the role of Eph receptors in HNSCC progression…
View article: A network meta-analysis assessing the effectiveness of various radical and conservative surgical approaches regarding recurrence in treating solid/multicystic ameloblastomas
A network meta-analysis assessing the effectiveness of various radical and conservative surgical approaches regarding recurrence in treating solid/multicystic ameloblastomas Open
View article: Stem Cell-Based Tissue Engineering for Cleft Defects: Systematic Review and Meta-Analysis
Stem Cell-Based Tissue Engineering for Cleft Defects: Systematic Review and Meta-Analysis Open
This study aimed to analyze the efficacy of stem cell-based tissue engineering for the treatment of alveolar cleft (AC) and cleft palate (CP) defects in animal models. Systematic review and meta-analysis. Preclinical studies on alveolar cl…
View article: Silica nanocarrier-mediated intracellular delivery of rapamycin promotes autophagy-mediated M2 macrophage polarization to regulate bone regeneration
Silica nanocarrier-mediated intracellular delivery of rapamycin promotes autophagy-mediated M2 macrophage polarization to regulate bone regeneration Open
View article: Kappa-carrageenan-Functionalization of octacalcium phosphate-coated titanium Discs enhances pre-osteoblast behavior and osteogenic differentiation
Kappa-carrageenan-Functionalization of octacalcium phosphate-coated titanium Discs enhances pre-osteoblast behavior and osteogenic differentiation Open
Bioactive coatings are promising for improving osseointegration and the long-term success of titanium dental or orthopaedic implants. Biomimetic octacalcium phosphate (OCP) coating can be used as a carrier for osteoinductive agents. κ-Carr…
View article: Bone vitality and vascularization of mandibular and maxillary bone grafts in maxillary sinus floor elevation: A retrospective cohort study
Bone vitality and vascularization of mandibular and maxillary bone grafts in maxillary sinus floor elevation: A retrospective cohort study Open
Objectives Mandibular retromolar (predominantly cortical) and maxillary tuberosity (predominantly cancellous) bone grafts are used in patients undergoing maxillary sinus floor elevation (MSFE) for dental implant placement. The aim of this …
View article: Regenerative graft materials for maxillary sinus elevation in randomized clinical trials: A meta-analysis
Regenerative graft materials for maxillary sinus elevation in randomized clinical trials: A meta-analysis Open
View article: Radiation modulates expression and related activities of c-Met protein in oral tongue squamous cell carcinoma cell lines
Radiation modulates expression and related activities of c-Met protein in oral tongue squamous cell carcinoma cell lines Open
View article: Recurrent Ameloblastoma: Clinical Manifestation and Disease-Free Survival Rate
Recurrent Ameloblastoma: Clinical Manifestation and Disease-Free Survival Rate Open
Objectives. Ameloblastoma is a slow-growing epithelial odontogenic neoplasm of the jaws with a high recurrence rate. The main treatment strategies for this lesion are radical or conservative surgical approaches. The aim of the present stud…
View article: Virtual and traditional surgical planning in orthognathic surgery – systematic review and meta-analysis
Virtual and traditional surgical planning in orthognathic surgery – systematic review and meta-analysis Open
View article: <scp>WEE1</scp> kinase inhibitor <scp>MK</scp>‐1775 sensitizes oral tongue squamous cell carcinoma cells to radiation irrespective of <scp>TP53</scp> status
<span>WEE1</span> kinase inhibitor <span>MK</span>‐1775 sensitizes oral tongue squamous cell carcinoma cells to radiation irrespective of <span>TP53</span> status Open
Objective Oral tongue squamous cell carcinoma (OTSCC) frequently harbors non‐functional p53 and depends on G2/M checkpoint mediated by WEE1. WEE1 suppression has been identified as a promising anti‐tumor strategy. This study investigated t…
View article: Safety and feasibility study of using polyphosphate (PolyP) in alveolar cleft repair: a pilot study
Safety and feasibility study of using polyphosphate (PolyP) in alveolar cleft repair: a pilot study Open
View article: K-Carrageenan Stimulates Pre-Osteoblast Proliferation and Osteogenic Differentiation: A Potential Factor for the Promotion of Bone Regeneration?
K-Carrageenan Stimulates Pre-Osteoblast Proliferation and Osteogenic Differentiation: A Potential Factor for the Promotion of Bone Regeneration? Open
Current cell-based bone tissue regeneration strategies cannot cover large bone defects. K-carrageenan is a highly hydrophilic and biocompatible seaweed-derived sulfated polysaccharide, that has been proposed as a promising candidate for ti…
View article: Age-group-specific trend analyses of oropharyngeal squamous cell carcinoma incidence from 1989 to 2018 and risk factors profile by age-group in 2015–2018: a population-based study in The Netherlands
Age-group-specific trend analyses of oropharyngeal squamous cell carcinoma incidence from 1989 to 2018 and risk factors profile by age-group in 2015–2018: a population-based study in The Netherlands Open
Incidence of oropharyngeal squamous cell carcinoma (OPSCC) is increasing globally and the human papillomavirus (HPV) has been linked to this increase. This study aimed to present a comprehensive overview of OPSCC trends in incidence rates …
View article: Polyphosphate (PolyP) for alveolar cleft repair: study protocol for a pilot randomized controlled trial
Polyphosphate (PolyP) for alveolar cleft repair: study protocol for a pilot randomized controlled trial Open
View article: A population-based study of the epidemiology of oral squamous cell carcinoma in the Netherlands 1989–2018, with emphasis on young adults
A population-based study of the epidemiology of oral squamous cell carcinoma in the Netherlands 1989–2018, with emphasis on young adults Open
There has been an increasing trend in oral squamous cell carcinoma (OSCC) in patients under 45 years of age. The aim of this study was to evaluate the burden of OSCC in the Netherlands between 1989 and 2018 among young adults (age 20-34 ye…
View article: Increased Osteogenic Potential of Pre-Osteoblasts on Three-Dimensional Printed Scaffolds Compared to Porous Scaffolds for Bone Regeneration
Increased Osteogenic Potential of Pre-Osteoblasts on Three-Dimensional Printed Scaffolds Compared to Porous Scaffolds for Bone Regeneration Open
The 3DP scaffolds show enhanced mechanical properties and ALP activity compared to porous scaffolds in vitro, suggesting that 3DP PLGA/β-TCP scaffolds are possibly more favorable for bone formation.
View article: A photo-crosslinkable cartilage-derived extracellular matrix bioink for auricular cartilage tissue engineering
A photo-crosslinkable cartilage-derived extracellular matrix bioink for auricular cartilage tissue engineering Open
View article: Short Pretreatment with Calcitriol Is Far Superior to Continuous Treatment in Stimulating Proliferation and Osteogenic Differentiation of Human Adipose Stem Cells.
Short Pretreatment with Calcitriol Is Far Superior to Continuous Treatment in Stimulating Proliferation and Osteogenic Differentiation of Human Adipose Stem Cells. Open
This study is the first research showing that 30 minutes pretreatment of hASCs with 1,25-(OH)2VitD3, not only enhanced cell attachment to the scaffold at seeding time, but also promoted the proliferation and osteogeni…