Explanipedia

Collimated and non-collimated proton minibeam irradiation using SIRMIO: a simulation study Open

Fardous Reaz, Ze Huang, Marco Pinto, J. Bortfeldt, Niels Bassler , et al. · 2025

Background and purpose: Successful clinical integration of pMBRT requires comprehensive investigations of the relationship between various pMBRT parameters and their associated biological effects. Such investigations are critically depende…

Spatio-Temporal Evolution of the March 2022 ICME Revealed by Multi-Point Observations of Forbush Decreases Open

Gaku Kinoshita, Beatriz Sánchez‐Cano, Yoshizumi Miyoshi, Laura Rodoriguez-Garcia, Emilia Kilpua , et al. · 2025

Interplanetary coronal mass ejections (ICMEs) cause Forbush Decreases (FDs) effects, which are local decreases in background galactic cosmic rays (GCR). Even though FDs can be observed with simple particle instruments, their amplitude and …

A novel thermochromic myocardial phantom for radiofrequency ablation and cryoablation Open

Carlo Saija, Sukruth Pradeep Kundur, Lisa Leung, Sachin Sabu, Marco Pinto , et al. · 2025

Experimental assessment of novel PET detector components for online imaging of radioactive ion beams Open

Giulio Lovatti, Munetaka Nitta, Francesco A. Evangelista, Daria Boscolo, D. Kostyleva , et al. · 2025

Objective. This work aims to evaluate the ability of novel detector components to measure with submillimeter resolution in beam positron emission tomography (PET) signals produced by 10 C and 11 C radioactive ion beams stopped in PMMA targ…

An analytical approach to predict 3D positron emitter distribution in carbon ion therapy Open

Tan-Tan Du, J. Bauer, Katia Parodi, Marco Pinto · 2025

Objective. Carbon ion therapy could benefit from range verification due to its sensitivity to range uncertainties. Positron emission tomography (PET) aids in this and comparing PET signals to a predicted positron emitter distribution (PED)…

Design and <i>in-silico</i> evaluation of a novel beamline for precision small animal pencil beam scanning delivery at clinical proton therapy facilities Open

Neeraj Kurichiyanil, Marco Pinto, Katia Parodi · 2025

Objectives. Preclinical small animal proton beam irradiation systems are increasingly in demand. However, the absence of dedicated systems comparable in precision to those in clinical settings presents a considerable hurdle to investigatio…

Patient CT-based simulation study of secondary-electron-bremsstrahlung imaging for range verification in proton therapy: comparison with prompt gamma and PET imaging for simplified proton pencil beam and SOBP irradiation scenarios Open

Takuya Yabe, Munetaka Nitta, Mitsutaka Yamaguchi, Marco Pinto, Naoki Kawachi , et al. · 2025

Objective. Secondary electron bremsstrahlung (SEB) imaging, along with prompt gamma (PG) and positron emission tomography (PET) imaging, has been proposed as an in vivo range verification tool for proton therapy. This study presents the fi…

The JUICE Radiation Environment Monitor, RADEM Open

Wojtek Hajdas, P. Gonçalves, Marco Pinto, Patryk Socha, R. Marcinkowski , et al. · 2025

A Novel Thermochromic Myocardial Phantom for Radiofrequency Ablation and Cryoablation Open

Carlo Saija, Sukruth Pradeep Kundur, Lisa Leung, Sachin Sabu, Marco Pinto , et al. · 2025

In the growing field of electrophysiology, cardiac ablation either via heating or freezing target tissues using catheters, induces localised scarring to block or destroy defective electrical pathways in the heart. To test equipment and abl…

The severity of degenerative disc disease at primary discectomy by lumbar disc herniation as a predictor of reintervention with spinal fusion surgery Open

Daniela Fortuna, B. Barros, L. Chorão, Marco Pinto, Raquel Duarte · 2025

Influence of Social Inclusion on Recycling Cycles of Circular Economy: Waste Picker Organizations in the Global South Open

Dánika A. Castillo-Ospina, Marco Pinto, Aldo Roberto Ometto · 2025

Prompt-gamma imaging in particle therapy Open

Marco Pinto · 2024

Prompt-gamma imaging has been a source of intensive research over the years since its first proposal in 2003. Several detection approaches have been researched and developed, and many studies on prompt-gamma imaging have been conducted on …

Evaluation of a Three-Dimensional Printed Interventional Simulator for Cardiac Ablation Therapy Training Open

Carlo Saija, Sachin Sabu, Lisa Leung, Ellie Lowe, Noor Al-Bahrani , et al. · 2024

Cardiac ablation (CA) is an interventional electrophysiological procedure used to disrupt arrhythmic substrates in the myocardium by inducing localized scarring. Current CA training relies on the master–apprentice model. In different field…

An experimental validation of a filtering approach for prompt gamma prediction in a research proton treatment planning system Open

Ze Huang, Liheng Tian, Guillaume Janssens, J. Smeets, Yunhe Xie , et al. · 2024

Objective. Prompt gamma (PG) radiation generated from nuclear reactions between protons and tissue nuclei can be employed for range verification in proton therapy. A typical clinical workflow for PG range verification compares the detected…

Space Weather monitoring with BepiColombo and JUICE during their cruise phases Open

Beatriz Sánchez‐Cano, Marco Pinto, Olivier Witasse, P. Gonçalves, Wojtek Hajdas , et al. · 2024

The space environment is known to be populated by highly energetic particles that may be hazardous for the health of missions and impact planetary environments. The effects of these particles are commonly known as Space Weather. Monitoring…

FIRST MEASUREMENT OF SECONDARY ELECTRON BREMSSTRAHLUNG TOWARDS IN-VIVO RANGE VERIFICATION IN PRECLINICAL SMALL ANIMAL PROTON THERAPY RESEARCH Open

Takuya Yabe, Munetaka Nitta, Mitsutaka Yamaguchi, J. Bortfeldt, Ze Huang , et al. · 2024

Improved modelling of SEP event onset within the WSA-Enlil-SEPMOD framework Open

Erika Palmerio, J. G. Luhmann, M. L. Mays, Ronald M. Caplan, D. Lario , et al. · 2024

Multi-spacecraft observations of solar energetic particle (SEP) events not only enable a deeper understanding and development of particle acceleration and transport theories, but also provide important constraints for model validation effo…

Design study of a novel geometrical arrangement for an in-beam small animal positron emission tomography scanner Open

Giulio Lovatti, Munetaka Nitta, Mohammad Javad Safari, Chiara Gianoli, Marco Pinto , et al. · 2023

Objective. We designed a geometrical solution for a small animal in-beam positron emission tomography (PET) scanner to be used in the project SIRMIO (Small animal proton irradiator for research in molecular image-guided radiation-oncology)…

The effect of the ambient solar wind medium on a CME-driven shock and the associated gradual solar energetic particle event Open

Nicolas Wijsen, D. Lario, Beatriz Sánchez‐Cano, Immanuel Christopher Jebaraj, N. Dresing , et al. · 2023

We present simulation results of a gradual solar energetic particle (SEP) event detected on 2021 October 9 by multiple spacecraft, including BepiColombo (Bepi) and near-Earth spacecraft such as the Advanced Composition Explorer (ACE). A pe…

Monitoring of Solar Energetic Particles and Cosmic Rays with the RADEM instrument onboard the ESA JUICE mission Open

Wojtek Hajdas, P. Gonçalves, Marco Pinto, André Galli, Olivier Witasse · 2023

The main goal of the radiation monitor RADEM flying onboard the ESA JUICE mission is to provide continuous information on particle fluxes and their energy spectra. The monitor measures electrons up to 40 MeV and protons up to 250 MeV. Such…

Geografia(s) em Diálogo III Encontro Nacional de Estudantes de Geografia (ENEG’23) Open

João Leal, Marco Pinto, Paulo Lemos · 2023

Geography Students’ National Meetings are not new in our country. Contrary to what would be expected for a century-old science, until recently, a National Geography Student Meeting had not yet been organized, at least formally, a gap fille…

Smooth online parameter estimation for time varying VAR models with application to rat local field potential activity data Open

Anass El Yaagoubi Bourakna, Marco Pinto, Norbert J. Fortin, Hernando Ombao · 2023

Multivariate time series data appear often as realizations of non-stationary processes where the covariance matrix or spectral matrix smoothly evolve over time. Most of the current approaches estimate the time-varying spectral properties o…

BepiColombo as upstream solar wind monitor for Mars’ ionosphere Open

Beatriz Sánchez‐Cano, M. Lester, Simon Joyce, Olivier Witasse, J. Benkhoff , et al. · 2022

<p>BepiColombo is a joint mission of the European Space Agency (ESA) and the Japan Aerospace Exploration Agency (JAXA) to the planet Mercury. It was launched in October 2018 and it is due to arrive at Mercury in late 2025. It consist…

First Analysis of Solar Energetic Particles with the BepiColombo Radiation Monitor (BERM) Open

C. Cardoso, Marco Pinto, P. Gonçalves, Beatriz Sánchez‐Cano, Richard Moissl , et al. · 2022

<p>December 2019 marked the beginning of Solar Cycle 25. Since then, the Sun´s activity has been ramping up with multiple Coronal Mass Ejections (CMEs), Solar Flares, and Solar Energetic Particle (SEP) events having been reg…

Depth dose measurements in water for 11C and 10C beams with therapy relevant energies Open

Daria Boscolo, D. Kostyleva, Christoph Schuy, Uli Weber, E. Haettner , et al. · 2022

Owing to the favorable depth-dose distribution and the radiobiological properties of heavy ion radiation, ion beam therapy shows an improved success/toxicity ratio compared to conventional radiotherapy. The sharp dose gradients and very hi…

Applications of a patient-specific whole-body CT-mesh hybrid computational phantom in second cancer risk prediction Open

Erika Kollitz, Moritz Roew, Haegin Han, Marco Pinto, Florian Kamp , et al. · 2022

Objective. CT-mesh hybrid phantoms (or ‘hybrid(s)’) made from integrated patient CT data and mesh-type reference computational phantoms (MRCPs) can be beneficial for patient-specific whole-body dose evaluation, but this benefit has yet to …

A patient-specific hybrid phantom for calculating radiation dose and equivalent dose to the whole body Open

Erika Kollitz, Haegin Han, Chan Hyeong Kim, Marco Pinto, Marco Schwarz , et al. · 2021

Objective . As cancer survivorship increases, there is growing interest in minimizing the late effects of radiation therapy such as radiogenic second cancer, which may occur anywhere in the body. Assessing the risk of late effects requires…

A computational hyperspectral structured light sheet microscope Open

Sébastien Crombez, Pierre Leclerc, Marco Pinto, Nicolas Ducros · 2021

We describe here a hyperspectral light sheet microscope that is based on beam shaping and image reconstruction. Our approach has no moving parts and can be easily combined with a standard microscope.

Corrigendum: Beam characterization and feasibility study for a small animal irradiation platform at clinical proton therapy facilities (2020 Phys. Med. Biol. 65 245045) Open

Sonja Gerlach, Marco Pinto, Neeraj Kurichiyanil, Cai Grau, J. Hérault , et al. · 2021

In our paper (Gerlach et al 2020) we demonstrated the capability of a proposed novel active beamline to be used with proton beams from different proton therapy centres for producing suitable beams for small animal irradiation. In this cont…

Issue Information Open

D Nina, Mirasol Matela, Werner G. Daniel, Eiji Yashima, Zhiqiang Zhou , et al. · 2021

No abstract is available for this article.

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