Marco Redaelli
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View article: Three in a Bed: Can Partner Support Improve CPAP Adherence? A Systematic Review and Intervention Recommendations
Three in a Bed: Can Partner Support Improve CPAP Adherence? A Systematic Review and Intervention Recommendations Open
Background/Objectives: Continuous positive airway pressure (CPAP) is the standard approach for treating obstructive sleep apnea syndrome (OSAS), but patient adherence is often low due to various influencing factors. Recently, researchers h…
View article: Anticancer Effects of Wild Mountain Mentha longifolia Extract in Adrenocortical Tumor Cell Models
Anticancer Effects of Wild Mountain Mentha longifolia Extract in Adrenocortical Tumor Cell Models Open
Mint [Mentha longifolia (L.) Hudson] is an aromatic plant that belongs to Lamiaceae family. It is traditionally used as herbal tea in Europe, Australia and North Africa and shows numerous pharmacological effects, such as spasmolytic, antio…
View article: Preclinical Activities of Epigallocatechin Gallate in Signaling Pathways in Cancer
Preclinical Activities of Epigallocatechin Gallate in Signaling Pathways in Cancer Open
Epigallocatechin gallate (EGCG) is the main bioactive component of catechins predominantly present in various types of tea. EGCG is well known for a wide spectrum of biological activities as an anti-oxidative, anti-inflammatory, and anti-t…
View article: Liposomal Cytarabine as Cancer Therapy: From Chemistry to Medicine
Liposomal Cytarabine as Cancer Therapy: From Chemistry to Medicine Open
Cancer is the second leading cause of death worldwide. The main modality to fight against cancer is surgery, radiotherapy, and chemotherapy, and more recently targeted therapy, gene therapy and immunotherapy, which play important roles in …
View article: Biological Effects of EF24, a Curcumin Derivative, Alone or Combined with Mitotane in Adrenocortical Tumor Cell Lines
Biological Effects of EF24, a Curcumin Derivative, Alone or Combined with Mitotane in Adrenocortical Tumor Cell Lines Open
Background: Curcumin has numerous properties and is used in many preclinical conditions, including cancer. It has low bioavailability, while its derivative EF24 shows enhanced solubility. However, its effects have never been explored in ad…
View article: Antiproliferative activity of Juglone derivatives on rat glioma
Antiproliferative activity of Juglone derivatives on rat glioma Open
Malignant gliomas are aggressive and life-threatening tumours that still show a poor prognosis: the current therapeutic approach based on surgical resection and chemotherapy combined with radiotherapy does not provide a satisfactory chance…
View article: Major Urinary Proteins on Nanodiamond-Based Resonators Toward Artificial Olfaction
Major Urinary Proteins on Nanodiamond-Based Resonators Toward Artificial Olfaction Open
A new bio-sensing platform based on major uri- nary proteins (MUPs) from the mouse as chemical recognition elements has been developed. The transducers were surface acoustic devices coated with diamond nanoparticles as an inter- mediate la…
View article: CCDC 976853: Experimental Crystal Structure Determination
CCDC 976853: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 976852: Experimental Crystal Structure Determination
CCDC 976852: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Molecular Targets in Glioblastoma
Molecular Targets in Glioblastoma Open
Glioblastoma is the most lethal brain tumor. The poor prognosis results from lack of defined tumor margins, critical location of the tumor mass and presence of chemo- and radio-resistant tumor stem cells. The current treatment for glioblas…
View article: Serotonin and Noradrenaline Reuptake Inhibitors Improve Micturition Control in Mice
Serotonin and Noradrenaline Reuptake Inhibitors Improve Micturition Control in Mice Open
Poor micturition control may cause profound distress, because proper voiding is mandatory for an active social life. Micturition results from the subtle interplay of central and peripheral components. It involves the coordination of autono…
View article: Mitogen-Activated Protein Kinase Pathway: Genetic Analysis of 95 Adrenocortical Tumors
Mitogen-Activated Protein Kinase Pathway: Genetic Analysis of 95 Adrenocortical Tumors Open
Mitogen-activated protein kinase (MAPK) pathway is often deregulated in adrenocortical tumors (ACT) but with no concrete data confirming alteration rate. The objective of this study was to evaluate genetic alterations in key components of …