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View article: Development, Safety, and Therapeutic Evaluation of Voriconazole-Loaded Zein–Pectin–Hyaluronic Acid Nanoparticles Using Alternative In Vivo Models for Efficacy and Toxicity
Development, Safety, and Therapeutic Evaluation of Voriconazole-Loaded Zein–Pectin–Hyaluronic Acid Nanoparticles Using Alternative In Vivo Models for Efficacy and Toxicity Open
Background/Objectives: Fungal infections caused by Candida species remain a significant clinical challenge, exacerbated by limitations in current antifungal therapies, including toxicity and poor bioavailability. This study aimed to develo…
View article: Investigation of Antifungal Susceptibility Profile in Fungi Isolated from Patients with Chronic Wounds: A Focus on Venous Ulcers
Investigation of Antifungal Susceptibility Profile in Fungi Isolated from Patients with Chronic Wounds: A Focus on Venous Ulcers Open
Background: The complexity and challenges in managing patients with chronic wounds, combined with high morbidity rates, make this condition a significant public health issue. The polymicrobial presence of microorganisms, particularly fungi…
View article: AVALIAÇÃO A EFICÁCIA DO PAPANICOLAU NA DETECÇÃO DE LESÕES CAUSADAS POR HPV
AVALIAÇÃO A EFICÁCIA DO PAPANICOLAU NA DETECÇÃO DE LESÕES CAUSADAS POR HPV Open
Introdução: Diagnóstico da infecção pelo Papilomavirus ( HPV) pode ser feito através de exames laboratoriais, histopatológicos e de biologia molecular.A citologia oncótica convencional (CC) é exame de fácil aplicabilidade e diminui a morta…
View article: OS DESAFIOS NA CONDUTA TERAPÊUTICA EM PACIENTES ACOMETIDOS COM FERIDAS CRÔNICAS
OS DESAFIOS NA CONDUTA TERAPÊUTICA EM PACIENTES ACOMETIDOS COM FERIDAS CRÔNICAS Open
Considerado um grave problema em saúde pública, as feridas crônicas são patologias que desafiam o manejo terapêutico e infelizmente acometem milhares de pessoas em todo o mundo. Essa doença apresenta altos índices de morbidade impactando n…
View article: Relation between CANDIDA species isolated from vaginal mucosa and lesions caused by high-risk human papillomavirus hpv for cervical cancer
Relation between CANDIDA species isolated from vaginal mucosa and lesions caused by high-risk human papillomavirus hpv for cervical cancer Open
This study characterized and related yeasts of the genus Candida isolated from vaginal mucous membranes of women with lesions caused by high-risk HPV for cervical cancer. Forty-two women treated at the Lower Genital Tract Pathology Clinic …
View article: Difference Between the Profiles Presented by Yeasts that Colonize the Vaginal Mucosa or Cause Primary or Recurrent Candidiasis
Difference Between the Profiles Presented by Yeasts that Colonize the Vaginal Mucosa or Cause Primary or Recurrent Candidiasis Open
View article: Antimicrobial activity of Wickerhamomyces anomalus mycocins against strains of Staphylococcus aureus isolated from meats
Antimicrobial activity of Wickerhamomyces anomalus mycocins against strains of Staphylococcus aureus isolated from meats Open
Staphylococcus aureus is among the major pathogens involved in food poisoning, and meat contaminated with S. aureus coagulase positive is considered a public health risk because the bacterium is resistant to several conventional antimicrob…
View article: The Rise of Fungi: Evidence on the Global Scale. Old Known Silences or Mysterious Threats to the Planet
The Rise of Fungi: Evidence on the Global Scale. Old Known Silences or Mysterious Threats to the Planet Open
Introduction: Fungi are organisms that present themselves in multicellular macroscopic and unicellular microscopic forms. They are eukaryotic, heterotrophic, reproduce asexually/sexually, cosmopolitan, achlorophyllates and are present in v…
View article: Antimicrobial activity of Wickerhamomyces anomalus mycocins against strains of Staphylococcus aureus isolated from meats
Antimicrobial activity of Wickerhamomyces anomalus mycocins against strains of Staphylococcus aureus isolated from meats Open
Staphylococcus aureus is among the major pathogens involved in food poisoning, and meat contaminated with S. aureus coagulase positive is considered a public health risk because the bacterium is resistant to several conventional antimicrob…
View article: MULTICENTER STUDY OF CANDIDA SPECIES IN ORAL MUCOSA OF DIFFERENT PATIENTS: ANALYSIS OF 711 STRAINS AND LITERATURE REVIEW
MULTICENTER STUDY OF CANDIDA SPECIES IN ORAL MUCOSA OF DIFFERENT PATIENTS: ANALYSIS OF 711 STRAINS AND LITERATURE REVIEW Open
This study aimed to identify Candida spp. collected from oral mucosa and maintained in culture collections, correlating the findings with the medical history of patients and comparing with data from the literature over the past five years.…
View article: <i>Cryptococcus</i> and <i>Cryptococcosis</i> in Human and Animal Model: An Overview
<i>Cryptococcus</i> and <i>Cryptococcosis</i> in Human and Animal Model: An Overview Open
Background: Yeasts from the genus Cryptococcus (species C. neoformans and C. gattii) are opportunistic pathogens that afflict humans with low immunity caused by diseases such as AIDS or by the usage of immunosuppressive drugs. It is a fata…
View article: <i>Apiotrichum veenhuisii</i> isolated from a pediatric patient with acute myeloid leukemia: The first case in humans
<i>Apiotrichum veenhuisii</i> isolated from a pediatric patient with acute myeloid leukemia: The first case in humans Open
This is the first report of the yeast Apiotrichum veenhuisii (formerly Trichosporon veenhuisii) causing disease in humans; its virulence and in vitro behavior against antifungals were also studied. The sample was isolated fro…
View article: SAÚDE ITINERANTE NOS CENTROS MUNICIPAIS DE EDUCAÇÃO INFANTIL DO MUNICÍPIO DE GUARAPUAVA - PR; OS DESAFIOS DA PROMOÇÃO DA SAÚDE EM CRIANÇAS EXPOSTAS A DOENÇAS PARASITÁRIAS
SAÚDE ITINERANTE NOS CENTROS MUNICIPAIS DE EDUCAÇÃO INFANTIL DO MUNICÍPIO DE GUARAPUAVA - PR; OS DESAFIOS DA PROMOÇÃO DA SAÚDE EM CRIANÇAS EXPOSTAS A DOENÇAS PARASITÁRIAS Open
A presença de enteroparasitoses em crianças em idade pré-escolar tem sido motivo de preocupação pelos órgãos de saúde principalmente devido ao impacto negativo sobre o crescimento e desenvolvimento intelectual dessas crianças. As infecções…
View article: Infections Caused by Fusarium Species in Pediatric Cancer Patients and Review of Published Literature
Infections Caused by Fusarium Species in Pediatric Cancer Patients and Review of Published Literature Open
View article: Characterization of Clinical and Environmental Isolates of &lt;i&gt;Cryptococcus neoformans&lt;/i&gt;/&lt;i&gt;Cryptococcus gattii&lt;/i&gt; Complex Maintained in Yeast Culture Collection in S&#227;o Paulo, Brazil
Characterization of Clinical and Environmental Isolates of <i>Cryptococcus neoformans</i>/<i>Cryptococcus gattii</i> Complex Maintained in Yeast Culture Collection in São Paulo, Brazil Open
Objective: As isolates of Cryptococcus are frequently kept collection stocks in institutions, sometimes without proper characterization, we sought to determine the genotype profiles, protease and phospholipase activities “in vitro” and the…
View article: PERFIL DAS MULHERES USUÁRIAS DO SUS COM LESÕES INTRAEPITELIAIS EM UM MUNICÍPIO DO OESTE DO PARANÁ
PERFIL DAS MULHERES USUÁRIAS DO SUS COM LESÕES INTRAEPITELIAIS EM UM MUNICÍPIO DO OESTE DO PARANÁ Open
O câncer cervical é o quarto tipo de tumor mais frequente entre mulheres e quarta causa de mortalidade feminina por câncer no Brasil. Neste trabalho o objetivo foi demostrar o perfil das mulheres atendidas pelo SUS que apresentaram lesões …
View article: Evaluation of infections by Candida at a university hospital of Vale do Paraíba region, São Paulo State, Brazil: species distribution, colonization, risk factors and antifungal susceptibility
Evaluation of infections by Candida at a university hospital of Vale do Paraíba region, São Paulo State, Brazil: species distribution, colonization, risk factors and antifungal susceptibility Open
The present research aimed to carry out an epidemiological study, recording the prevalence of Candida spp. causing infection, as well as the colonization, distribution of the different species in clinical specimens from different sectors o…
View article: Quercetin and rutin as potential agents antifungal against Cryptococcus spp
Quercetin and rutin as potential agents antifungal against Cryptococcus spp Open
Amphotericin B is a fungicidal substance that is treatment of choice for most systemic fungal infections affecting as cryptococcosis the immunocompromised patients. However, severe side effects have limited the utility of this drug. The ai…
View article: Cryptococcus gattii: immunological and microbiological study in a patient with neurocryptococcosis
Cryptococcus gattii: immunological and microbiological study in a patient with neurocryptococcosis Open
Introduction: Cryptococcal meningitis is a disease that remains a significant cause of morbidity and mortality. This report describes the importance of conducting a detailed clinical investigation and the treatment challenges in cases of m…