Explanipedia

Corneal Graft Rejection Open

Nicole Ming Sie, Marcus Ang · 2025

Bullous Keratopathy Open

Nicole Ming Sie, Marcus Ang, Arundhati Anshu · 2025

Infections: Onchocerciasis Open

Nicole Sie, Marcus Ang, Anshu Arundhati · 2025

Infections: Herpes Zoster Ophthalmicus (HZO) Open

Nicole Sie, Marcus Ang, Arundhati Anshu · 2025

Infections: Conjunctivitis Open

Nicole Sie, Marcus Ang, Arundhati Anshu · 2025

Chemical Injury Open

Nicole Sie, Marcus Ang, Anshu Arundhati · 2025

Structure-Function Associations of Choroidal Thickness With Retinal Sensitivity in Myopia Open

Syna Sreng, Joey Chung, Angeline Toh, Yvonne Ng Bei Zhen, Leila Sara Eppenberger , et al. · 2025

Significant associations between choroidal thickness measurements and microperimetry were observed in a cross-sectional cohort of myopic eyes, suggesting a structure-function relationship with retinal sensitivity at the choroid. Further st…

Optic Nerve Head Changes over 15 Years—From the Atropine Treatment Long-Term Assessment Study Open

Leila Sara Eppenberger, E Cheong, Joey Chung, Yong Li, Angeline Toh , et al. · 2025

Deep Learning Analysis of Widefield Cornea Endothelial Imaging in Fuchs Dystrophy Open

Kai Yuan Tey, Brian Juin Hsien Lee, Chen Fei Ng, Qiu Ying Wong, Satish K. Panda , et al. · 2025

The authors have no proprietary or commercial interest in any materials discussed in this article.

Proposed Nomenclature for Landmarks in Anterior-Segment OCT Open

Alexander S. Fraser, Marcus Ang, Alice Bellchambers, Colin J. Chu, Alastair K. Denniston , et al. · 2025

Importance Anterior-segment optical coherence tomography (AS-OCT) has broad clinical and research utility. The utility of quantitative data derived from AS-OCT is, however, dependent on the quality and consistency of the cumulative evidenc…

Gender-based differences in career paths, parenthood and perspectives on professional barriers among Asian ophthalmologists Open

Claire Peterson, Brian Sheng Yep Yeo, Shelley Yin-Hsi Chang, Rachel S. Chong, Marcus Ang , et al. · 2025

Background: Gender equality in Asia remains under-researched, especially within medical fields. This study explored gender-related differences among ophthalmologists in Asia. Design: Observational, cross-sectional survey study. Methods: An…

Psychometric Evaluation and Computerized Adaptive Testing Simulations of Myopic Refractive Intervention Quality of Life Item Banks Open

Ryan Eyn Kidd Man, Eva Fenwick, Khan Wen Goh, Peter M. L. Teo, Marcus Ang , et al. · 2025

MyoRICAT can provide a comprehensive measurement of the QoL impact of myopic refractive intervention modalities.

Corrigendum to “Controversies, consensuses and guidelines on Small Incision Lenticule Extraction (SMILE) by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) and the Asia-Pacific Myopia Society (APMS)” [Asia-Pac J Ophthalmol (2025) 100221] Open

Kelvin H. Wan, Xiaoying Wang, Kenny H.W. Lai, Jorge L. Alió, Marcus Ang , et al. · 2025

Controversies, consensuses and guidelines on Small Incision Lenticule Extraction (SMILE) by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) and the Asia-Pacific Myopia Society (APMS) Open

Kelvin H. Wan, Xiaoying Wang, Kenny H.W. Lai, Jorge L. Alió del Barrio, Marcus Ang , et al. · 2025

Myopia and high myopia trends in Chinese children and adolescents over 25 years: a nationwide study with projections to 2050 Open

Zhe Pan, Haolan Xian, Feng Li, Ziyao Wang, Zihan Li , et al. · 2025

National Natural Science Foundation of China (#82271086; #82388101; #72495123).

Corneal Layer Segmentation in Healthy and Pathological Eyes: A Joint Super-Resolution Generative Adversarial Network and Adaptive Graph Theory Approach Open

Khin Yadanar Win, Jipson Wong Hon Fai, Wong Qiu Ying, Chloe Chua Si Qi, Jacqueline Chua , et al. · 2025

Our method can provide precise thickness measurement of multiple corneal layers, which has the potential to improve DMEK monitoring and FECD diagnosis.

Key strategies to reduce the global burden of myopia: consensus from the international myopia summit Open

Leila Sara Eppenberger, Amanda Davis, Serge Resnikoff, Tien Yin Wong, Weizhong Lan , et al. · 2025

In this paper, we describe key strategies to guide global collaborative efforts to further reduce the burden of myopia and myopia-related visual impairment. A modified Delphi method was applied as an iterative multistage process to collect…

Aqueous Proteomic and Metabolomic Profiles in Low-Energy vs High-Energy Femtosecond Laser-Assisted Cataract Surgery Open

Chang Liu, Xinyue Wang, Hon Shing Ong, Marcus Ang, Soon-Phaik Chee , et al. · 2025

FLACS induced higher immunological and inflammatory responses, oxidative stress reactions, and mitochondrial fatty acid oxidative stress compared with controls. These differential effects were more pronounced when a higher laser energy was…

Distortion-Corrected Posterior Ocular Shape in Myopic Eyes Assessed by Ultrawide OCT Detects Deformations Associated With Vision-Threatening Changes Open

Bingyao Tan, Janika Shah, Ryan P. McNabb, Subramania Jayaraman, Damon Wing Kee Wong , et al. · 2024

Eyes exceeding 27.2 mm in length exhibit pronounced shape changes. Our framework can be seamlessly integrated into commercial OCTs for ocular shape deformation detection, which could aid in identifying eyes with pathologic myopia.

Pentacam and Corvis ST findings in myopic Chinese patients with different corneal diameters in Singapore Open

Elizabeth Wen Ling Lim, Hla Myint Htoon, Peng Yi Tan, Marcus Ang, Jodhbir S. Mehta , et al. · 2024

Purpose: To study the effect of corneal white-to-white diameter on Pentacam Scheimpflug cornea tomography and Corvis ST corneal visualization Scheimpflug technology parameters in myopic eyes. Methods: In this retrospective cross-sectional …

Anterior Segment Optical Coherence Tomography Angiography: A Review of Applications for the Cornea and Ocular Surface Open

Brian Juin Hsien Lee, Kai Yuan Tey, Ezekiel Ze Ken Cheong, Qiu Ying Wong, Chloe Si Qi Chua , et al. · 2024

Dye-based angiography is the main imaging modality in evaluating the vasculature of the eye. Although most commonly used to assess retinal vasculature, it can also delineate normal and abnormal blood vessels in the anterior segment disease…

Effect of childhood atropine treatment on adult choroidal thickness using sequential deep learning-enabled segmentation Open

Yong Li, Damon Wing Kee Wong, Syna Sreng, Joey Chung, Angeline Toh , et al. · 2024

This study demonstrated that short-term (2-4 years) atropine treatment during childhood was associated with an increase in choroidal thickness of 20-40 μm in adulthood (10-20 years later), after adjusting for age, sex, and axial length. We…

Anterior Segment Optical Coherence Tomography Angiography: A Review of Applications for the Cornea and Ocular Surface Open

Brian Juin Hsien Lee, Kai Yuan Tey, Ezekiel Ze Ken Cheong, Qiu Ying Wong, Si Qi Chua , et al. · 2024

Dye-based angiography is the main imaging modality in evaluating the vasculature of the eye. Although most commonly used to assess retinal vasculature, it can also delineate normal and abnormal blood vessels in the anterior segment disease…

A deep learning system for myopia onset prediction and intervention effectiveness evaluation in children Open

Ziyi Qi, Tingyao Li, Jun Chen, Jason C. Yam, Yang Wen , et al. · 2024

Deep Learning‐Enabled Vasculometry Depicts Phased Lesion Patterns in High Myopia Progression Open

Hailong He, Yixin Liu, Hanruo Liu, Xiaomei Zhang, Hao Song , et al. · 2024

This study identified two distinct phases of retinal vascular morphological changes during the progression of HM. Traction lesions were predominant in the initial stage, while atrophic lesions were predominant in the later stage. These fin…

Comparison of manual and artificial intelligence-automated choroidal thickness segmentation of optical coherence tomography imaging in myopic adults Open

Zhi Wei Lim, Jonathan Li, Damon Wing Kee Wong, Joey Chung, Angeline Toh , et al. · 2024

Myopia Control: Are We Ready for an Evidence Based Approach? Open

Leila Sara Eppenberger, Andrzej Grzybowski, Leopold Schmetterer, Marcus Ang · 2024

Our review suggests that myopia control interventions are recommended and prescribed on the basis of accessibility and clinical practice patterns, which vary widely around the world. Clinical trials indicate short- to medium-term efficacy …

Neuropathic Corneal Pain: Tear Proteomic and Neuromediator Profiles, Imaging Features, and Clinical Manifestations Open

Chang Liu, Molly Tzu-Yu Lin, Isabelle Xin Yu Lee, Jipson Hon Fai Wong, Daqian Lu , et al. · 2024

Deep learning for detection of Fuchs endothelial dystrophy from widefield specular microscopy imaging: a pilotstudy Open

Valencia Hui Xian Foo, Gilbert Yong San Lim, Yu‐Chi Liu, Hon Shing Ong, Evan Wong , et al. · 2024

Potential applications of artificial intelligence in image analysis in cornea diseases: a review Open

Kai Yuan Tey, Ezekiel Ze Ken Cheong, Marcus Ang · 2024

Artificial intelligence (AI) is an emerging field which could make an intelligent healthcare model a reality and has been garnering traction in the field of medicine, with promising results. There have been recent developments in machine l…

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