Marcus Ehrström
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Staphylococcus lugdunensis does not exert competitive exclusion on human corneocytes Open
Human skin is our primary physical barrier and largest immune organ, and it also hosts a protective microbiota. Staphylococci are prominent members of the skin microbiota, including the ubiquitous coagulase-negative staphylococci (CoNS). T…
Tissue resident cells differentiate S. aureus from S. epidermidis via IL-1β following barrier disruption in healthy human skin Open
The Staphylococcus sp . are a dominant part of the human skin microbiome and present across the body. Staphylococcus epidermidis is a ubiquitous skin commensal, while S . aureus is thought to colonize at least 30% of the population. S . au…
Tissue resident cells differentiate S. aureus from S. epidermidis via IL-1beta following barrier disruption in healthy human skin disruption in healthy human skin Open
The Staphylococcus species are a dominant part of the human skin microbiome and present across all body sites. Staphylococcus epidermidis is a ubiquitous skin commensal, while S. aureus is thought to colonize at least 30% of the population…
Skin infiltrating NK cells in cutaneous T-cell lymphoma are increased in number and display phenotypic alterations partially driven by the tumor Open
Cutaneous T-cell lymphomas (CTCL) are characterized by focal infiltration of malignant T cell clones in solitary skin lesions. Many CTCL patients experience an indolent disease, but some progress to advanced disease with high fatality. We …
View article: Graded expression of the chemokine receptor CX3CR1 marks differentiation states of human and murine T cells and enables cross-species interpretation
Graded expression of the chemokine receptor CX3CR1 marks differentiation states of human and murine T cells and enables cross-species interpretation Open
T cells differentiate into functionally distinct states upon antigen encounter. These states are delineated by different cell surface markers for murine and human T cells, which hamper cross-species translation of T cell properties. We aim…
Baricitinib Blocks Cytokine-Mediated Downregulation of PAD1 in Human Keratinocytes: A Possible Molecular Link to the Effects of JAK Inhibitors in Atopic Dermatitis Open
Atopic dermatitis (AD) is one of the most common chronic inflammatory skin conditions in high-income countries. It has a complex etiology, with genetic, immunologic, and environmental factors causing skin barrier disruption and immune dysr…
View article: T cells in resolved allergic contact dermatitis steer tissue inflammation and <scp>MMP</scp>‐12–driven tissue modulation
T cells in resolved allergic contact dermatitis steer tissue inflammation and <span>MMP</span>‐12–driven tissue modulation Open
Tissue resident memory T cells contribute to localized immunity in barrier tissues such as the skin1 but are also implicated in local relapse of focal inflammatory skin diseases, including allergic contact dermatitis (ACD) and psoriasis.2-…
Vancomycin‐Loaded Microneedle Arrays against Methicillin‐Resistant <i>Staphylococcus Aureus</i> Skin Infections Open
Skin and soft tissue infections (SSTIs) caused by methicillin‐resistant Staphylococcus aureus (MRSA) are a major healthcare burden, often treated with intravenous injection of the glycopeptide antibiotic vancomycin (VAN). However, low loca…
Surgical Training and Standardised Management Guidelines Improved the 30‐Day Complication Rate After Abdominoplasty for Massive Weight Loss Open
Background An increasing number of patients need reconstructive surgery after massive weight loss. The hypothesis was that surgical experience together with standardised management guidelines significantly decreases early complication rate…