Marcus Eng Hock Ong
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View article: Pan-Asian Resuscitation Outcomes Study (PAROS)
Pan-Asian Resuscitation Outcomes Study (PAROS) Open
View article: Physical, psychological, cognitive, social health outcomes, and health-related quality of life in out-of-hospital cardiac arrest survivors and co-survivors: 3-month outcomes from the Quality Cardiac Arrest Survivorship cohort study (QualiCAS)
Physical, psychological, cognitive, social health outcomes, and health-related quality of life in out-of-hospital cardiac arrest survivors and co-survivors: 3-month outcomes from the Quality Cardiac Arrest Survivorship cohort study (QualiCAS) Open
View article: Immune-related adverse events are a potent predictor of post-transplant rejection in HCC: a multicentre retrospective cohort study
Immune-related adverse events are a potent predictor of post-transplant rejection in HCC: a multicentre retrospective cohort study Open
Background Immune checkpoint inhibitors (ICIs) enable successful hepatocellular carcinoma (HCC) downstaging or bridging for liver transplantation (LT) but increase allograft rejection risk. Although immune-related adverse events (irAEs) re…
View article: Machine learning for sudden cardiac death prediction among older adults using community-based electronic health records
Machine learning for sudden cardiac death prediction among older adults using community-based electronic health records Open
ML models can significantly enhance the prediction of SCD risk using community-based EHRs. Our proposed risk model may enable the identification of high-risk individuals among older adults, facilitating targeted interventions and personali…
View article: Building a coronavirus disease 2019 healthcare registry in an evolving pandemic
Building a coronavirus disease 2019 healthcare registry in an evolving pandemic Open
COVID-19 emerged in Wuhan, China in December 2019 and was declared a pandemic on March 11, 2020. As there were many unknowns about COVID-19, an immediate priority early in the pandemic was to collect high-quality data to understand disease…
View article: Prehabilitation of frail elderly PAtients undergoing majoR surgEry at HOME (PREPARE-HOME): a superiority parallel-group randomised controlled trial protocol evaluating smart wearable enhanced prehabilitation versus usual care
Prehabilitation of frail elderly PAtients undergoing majoR surgEry at HOME (PREPARE-HOME): a superiority parallel-group randomised controlled trial protocol evaluating smart wearable enhanced prehabilitation versus usual care Open
Introduction Frailty is a key predictor of adverse surgical outcomes in older adults, contributing to increased postoperative complications, prolonged hospitalisation and delayed recovery. Prehabilitation—targeting improvements in physical…
View article: Environmental sustainability in asthma: reducing carbon footprint and medication wastage
Environmental sustainability in asthma: reducing carbon footprint and medication wastage Open
Introduction Asthma inhalers are significant contributors of greenhouse gas emissions. However, less is known about the potentially avoidable carbon footprint i.e. medication wastage and oversupply. We aimed to analyse dispensing patterns …
View article: Developing federated time-to-event scores using heterogeneous real-world survival data
Developing federated time-to-event scores using heterogeneous real-world survival data Open
This study demonstrates the effectiveness of our privacy-preserving federated survival score generation framework and its applicability to real-world heterogeneous survival data.
View article: Association of Scene Time Interval and Field Arrival to Epinephrine Administration Time with Outcomes in Cardiac Arrest
Association of Scene Time Interval and Field Arrival to Epinephrine Administration Time with Outcomes in Cardiac Arrest Open
Background/Objectives: The association of scene time interval (STI) and field arrival to epinephrine administration time (FET) with outcomes in out-of-hospital cardiac arrest (OHCA) is unknown. The goal of this investigation is to assess t…
View article: Evaluation of cardiopulmonary resuscitation and automated external defibrillator skill retention with simplified community-based training
Evaluation of cardiopulmonary resuscitation and automated external defibrillator skill retention with simplified community-based training Open
Introduction: This study aimed to assess the retention of dispatcher-assisted cardiopulmonary resuscitation (CPR) skills and knowledge among newly trained laypersons in Singapore who were trained using the Dispatcher-Assisted first REspond…
View article: Missing Data in OHCA Registries: How Imputation Methods Affect Research Conclusions—Paper I
Missing Data in OHCA Registries: How Imputation Methods Affect Research Conclusions—Paper I Open
Background/Objectives: Clinical observational studies often encounter missing data, which complicates association evaluation with reduced bias while accounting for confounders. This is particularly challenging in multi-national registries …
View article: FairFML: fair federated machine learning with a case study on reducing gender disparities in cardiac arrest outcome prediction
FairFML: fair federated machine learning with a case study on reducing gender disparities in cardiac arrest outcome prediction Open
View article: Positivity rates and subsequent patient dispositions after utilisation of cervical spine imaging referral guidelines in Singapore
Positivity rates and subsequent patient dispositions after utilisation of cervical spine imaging referral guidelines in Singapore Open
Objectives This study seeks to evaluate the imaging characteristics and patient outcomes from the imaging recommendations of the ACR Appropriateness Criteria (AC), the ESR iGuide, and RCR iRefer. Materials and methods This retrospective st…
View article: Clinical and economic impact of a large language model in perioperative medicine: a randomized crossover trial
Clinical and economic impact of a large language model in perioperative medicine: a randomized crossover trial Open
Preoperative assessment is a critical but time-consuming component of perioperative care, often hindered by poor guideline adherence and high documentation burdens. This study evaluates the impact of PEACH (PErioperative AI CHatbot), an LL…
View article: Development and validation of a novel prognostic model to predict 1-year post-transplant mortality for acute-on-chronic hepatitis B liver failure: a nationwide, multicentre, cohort study
Development and validation of a novel prognostic model to predict 1-year post-transplant mortality for acute-on-chronic hepatitis B liver failure: a nationwide, multicentre, cohort study Open
View article: Public health insights of patients with asthma receiving primary, specialist or mixed care in Singapore using data from the SDG-CARE Asthma Registry
Public health insights of patients with asthma receiving primary, specialist or mixed care in Singapore using data from the SDG-CARE Asthma Registry Open
Findings of this study provide greater understanding of the asthma public healthcare landscape in Singapore, allowing for the identification of current gaps in care, particularly for high-risk groups that may benefit from optimised treatme…
View article: Ambulance diversion and its use as an ED overcrowding mitigation strategy: Does it work? A scoping review.
Ambulance diversion and its use as an ED overcrowding mitigation strategy: Does it work? A scoping review. Open
View article: Efficient design of automated guided vehicle systems in operating theatres via discrete events simulation
Efficient design of automated guided vehicle systems in operating theatres via discrete events simulation Open
The integration of Automated Guided Vehicles (AGVs) into healthcare facilities has demonstrated significant benefits, particularly in environments with high internal transportation volumes. Research indicates the implementation of AGVs in …
View article: Serial proteomic and metabolomic profiling for early neuroprognostication after out-of-hospital cardiac arrest: a prospective observational study
Serial proteomic and metabolomic profiling for early neuroprognostication after out-of-hospital cardiac arrest: a prospective observational study Open
View article: Utilising artificial intelligence in prehospital emergency care systems in low- and middle-income countries: a scoping review
Utilising artificial intelligence in prehospital emergency care systems in low- and middle-income countries: a scoping review Open
Introduction Improvements in prehospital emergency care have the potential to transform patient outcomes globally, but particularly within low-and middle-income countries. Whilst artificial intelligence is being implemented in many healthc…
View article: A scoping review and evidence gap analysis of clinical AI fairness
A scoping review and evidence gap analysis of clinical AI fairness Open
View article: Long-Range Forecasting for Emergency Care Systems in a Highly Dynamic Setting: A Singapore Case Study
Long-Range Forecasting for Emergency Care Systems in a Highly Dynamic Setting: A Singapore Case Study Open
In the long term, an overall increase in ECS demand is driven by an increase in high-acuity use; population health interventions can further exacerbate the high-acuity burden. Our work casts light on the relatively less-studied dynamics of…
View article: Pragmatic Risk Stratification Method to Identify Emergency Department Presentations for Alternative Care Service Pathways: Registry-Based Retrospective Study Over 5 Years
Pragmatic Risk Stratification Method to Identify Emergency Department Presentations for Alternative Care Service Pathways: Registry-Based Retrospective Study Over 5 Years Open
Background Redirecting avoidable presentations to alternative care service pathways (ACSPs) may lead to better resource allocation for prehospital emergency care. Stratifying emergency department (ED) presentations by admission risk using …
View article: Optimising design of clinical decision support systems and implementation strategies to improve radiological imaging appropriateness – A qualitative study in the emergency department
Optimising design of clinical decision support systems and implementation strategies to improve radiological imaging appropriateness – A qualitative study in the emergency department Open
Participants expressed their expectations regarding the design and features of CDSS as end users. Many strategies to optimise the implementation of CDSS in the ED for appropriate imaging exist and can encourage acceptance by ED physicians.
View article: Leveraging AI and Transfer Learning to Enhance Outcome Prediction for Out-of-Hospital Cardiac Arrest in Diverse Settings: Insights from the Pan-Asian Resuscitation Outcomes Study
Leveraging AI and Transfer Learning to Enhance Outcome Prediction for Out-of-Hospital Cardiac Arrest in Diverse Settings: Insights from the Pan-Asian Resuscitation Outcomes Study Open
Background Access to trustworthy artificial intelligence (AI) models for clinical applications like emergency care is unevenly distributed globally due to healthcare inequities. Low-resource settings face challenges in AI model development…
View article: Characteristics of pediatric patients with heat-related illness transferred to emergency departments: Descriptive analysis
Characteristics of pediatric patients with heat-related illness transferred to emergency departments: Descriptive analysis Open
Most pediatric cases with heat-related illness were middle or high school-aged, occurred in August and were related to outdoor sports activity. Patients admitted to hospitals suffered from altered consciousness status, dehydration and acut…
View article: Cardiometabolic multimorbidity and the risk of sudden cardiac death among geriatric community dwellers using longitudinal EHR-derived data
Cardiometabolic multimorbidity and the risk of sudden cardiac death among geriatric community dwellers using longitudinal EHR-derived data Open
Background Cardiometabolic multimorbidity (CMM) has increased globally in recent years, especially among geriatric community dwellers. However, it is currently unclear how SCD risk is impacted by CMM in older adults. This study aimed to ex…
View article: Epidemiology and outcomes of out-of-hospital cardiac arrest in Zhejiang, China based on Electronic Medical Record Surveillance
Epidemiology and outcomes of out-of-hospital cardiac arrest in Zhejiang, China based on Electronic Medical Record Surveillance Open
View article: Leveraging Electronic Health Records to Examine the Real-World Rates of Cancer Genetics Referrals in a Singapore Health Care Cluster
Leveraging Electronic Health Records to Examine the Real-World Rates of Cancer Genetics Referrals in a Singapore Health Care Cluster Open
PURPOSE Identifying patients with hereditary cancer syndromes through genetics referral enhances early detection and reduces healthcare costs. Despite potential benefits, genetics referral rates globally, including Singapore, remain low. T…
View article: Relationship intervention moderates the association between substance use and biological aging among Black adults.
Relationship intervention moderates the association between substance use and biological aging among Black adults. Open
ProSAAF mitigated some of the harmful effects of substance use on accelerated aging among Black couples, particularly among those with lower preintervention relationship satisfaction. These findings highlight the potential for relationship…