Marcus H. Cunningham
YOU?
Author Swipe
View article: D131. Breast Cancer Surgery and Stage Change during the COVID-19 Pandemic: An Observational Cohort
D131. Breast Cancer Surgery and Stage Change during the COVID-19 Pandemic: An Observational Cohort Open
PURPOSE: The COVID-19 pandemic restricted non-emergent surgery and increased time-to-surgery (TSS). Resultant changes in medical and surgical breast cancer treatment during this time warrant further characterization to optimize care. Our s…
View article: Genomic Epidemiology and Serology Associated with a SARS-CoV-2 R.1 Variant Outbreak in New Jersey
Genomic Epidemiology and Serology Associated with a SARS-CoV-2 R.1 Variant Outbreak in New Jersey Open
The neutralizing capacities of monoclonal antibodies used to treat COVID-19 and of those recovered from previously infected and vaccinated individuals against SARS-CoV-2 variants of concern (VOCs) remain important questions. We report on a…
View article: An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses
An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses Open
The devastation caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made clear the importance of pandemic preparedness. To address future zoonotic outbreaks due to related viruses in the sarbecovirus subgenus, we ide…
View article: Isolation and comparative analysis of antibodies that broadly neutralize sarbecoviruses
Isolation and comparative analysis of antibodies that broadly neutralize sarbecoviruses Open
The devastation caused by SARS-CoV-2 has made clear the importance of pandemic preparedness. To address future zoonotic outbreaks due to related viruses in the sarbecovirus subgenus, we identified a human monoclonal antibody, 10-40, that n…
View article: Emergence of Multiple SARS-CoV-2 Antibody Escape Variants in an Immunocompromised Host Undergoing Convalescent Plasma Treatment
Emergence of Multiple SARS-CoV-2 Antibody Escape Variants in an Immunocompromised Host Undergoing Convalescent Plasma Treatment Open
Over a year of the COVID-19 pandemic, distinct severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineages have arisen in multiple geographic areas around the world. SARS-CoV-2 variants of concern (VOCs), i.e., B.1.1.7 (alpha), B…
View article: Antifungal Drug Susceptibility and Genetic Characterization of Fungi Recovered from COVID-19 Patients
Antifungal Drug Susceptibility and Genetic Characterization of Fungi Recovered from COVID-19 Patients Open
Fungal infections are common complications of respiratory viral infections and are associated with the increased need for intensive care and elevated mortality. Data regarding microbiological and molecular characteristics of such infection…
View article: Post-vaccination SARS-COV-2 among healthcare workers in New Jersey: a genomic epidemiological study
Post-vaccination SARS-COV-2 among healthcare workers in New Jersey: a genomic epidemiological study Open
Emergence of SARS-CoV-2 with high transmission and immune evasion potential, the so-called Variants of Concern (VOC), is a major concern. We describe the early genomic epidemiology of SARS-CoV-2 recovered from vaccinated healthcare profess…
View article: Molecular Evolution and Adaptation of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA) Sequence Type 9
Molecular Evolution and Adaptation of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA) Sequence Type 9 Open
Staphylococcus aureus sequence type 9 (ST9) is the main LA-MRSA clone spreading in the Asian continent. It can colonize and cause mild to severe infections both in animal and humans.
View article: Emergence of multiple SARS-CoV-2 antibody escape variants in an immunocompromised host undergoing convalescent plasma treatment
Emergence of multiple SARS-CoV-2 antibody escape variants in an immunocompromised host undergoing convalescent plasma treatment Open
SARS-CoV-2 Variants of Concerns (VOC), e.g., B.1.351 (20H/501Y.V2) and P1 (20J/501Y.V3), harboring N-terminal domain (NTD) or the receptor-binding domain (RBD) (e.g., E484K) mutations, exhibit reduced in vitro susceptibility to convalescen…
View article: A Novel Diagnostic Test to Screen SARS-CoV-2 Variants Containing E484K and N501Y Mutations
A Novel Diagnostic Test to Screen SARS-CoV-2 Variants Containing E484K and N501Y Mutations Open
Spike protein mutations E484K and N501Y carried by SARS-CoV-2 variants have been associated with concerning changes of the virus, including resistance to neutralizing antibodies and increased transmissibility. While the concerning variants…
View article: Diagnosis, clinical characteristics, and outcomes of COVID-19 patients from a large healthcare system in northern New Jersey
Diagnosis, clinical characteristics, and outcomes of COVID-19 patients from a large healthcare system in northern New Jersey Open
View article: A novel diagnostic test to screen SARS-CoV-2 variants containing E484K and N501Y mutations
A novel diagnostic test to screen SARS-CoV-2 variants containing E484K and N501Y mutations Open
Spike protein mutations E484K and N501Y carried by SARS-CoV-2 variants have been associated with concerning changes of the virus, including resistance to neutralizing antibodies and increased transmissibility. While the concerning variants…
View article: An Observational Study of COVID-19 from A Large Healthcare System in Northern New Jersey: Diagnosis, Clinical Characteristics, and Outcomes
An Observational Study of COVID-19 from A Large Healthcare System in Northern New Jersey: Diagnosis, Clinical Characteristics, and Outcomes Open
Background New Jersey was an early epicenter for the COVID-19 pandemic in the United States, yet information on hospitalized COVID-19 patients from this area is scarce. This study aimed to provide data on demographics and clinical features…