Marcus Herdener
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View article: Co-Boost: boosting and guiding neuroplasticity by combining ketamine with neurofeedback-assisted learning—towards an individualised and integrated pharmaco-psychotherapy for cocaine addiction: study protocol for a randomised, placebo-controlled, double-blind, parallel-group, single-centre trial
Co-Boost: boosting and guiding neuroplasticity by combining ketamine with neurofeedback-assisted learning—towards an individualised and integrated pharmaco-psychotherapy for cocaine addiction: study protocol for a randomised, placebo-controlled, double-blind, parallel-group, single-centre trial Open
View article: Co-Boost: Boosting and guiding neuroplasticity by combining ketamine with neurofeedback-assisted learning – towards an individualised and integrated pharmaco-psychotherapy for cocaine addiction: study protocol for a randomised, placebo-controlled, double-blind, parallel-group, single-centre trial
Co-Boost: Boosting and guiding neuroplasticity by combining ketamine with neurofeedback-assisted learning – towards an individualised and integrated pharmaco-psychotherapy for cocaine addiction: study protocol for a randomised, placebo-controlled, double-blind, parallel-group, single-centre trial Open
Background: Cocaine is the most frequently used stimulant worldwide, with increasing consumption rates in Europe. Cocaine use is associated with great harm to individuals and society. As of today, psychotherapeutic interventions for cocain…
View article: Psilocybin-assisted therapy for relapse prevention in alcohol use disorder: a phase 2 randomized clinical trial
Psilocybin-assisted therapy for relapse prevention in alcohol use disorder: a phase 2 randomized clinical trial Open
View article: N-acetylcysteine reduces prefrontal reactivity to cocaine cues in individuals with cocaine use disorder
N-acetylcysteine reduces prefrontal reactivity to cocaine cues in individuals with cocaine use disorder Open
Background Individuals with cocaine use disorder experience heightened motivation to pursue rewards tied to cocaine, often triggered by associated cues. Cue reactivity and subsequent craving significantly elevate the risk of substance use,…
View article: The Züri Can study: Can regulated cannabis sales promote lower-risk cannabis use? Mini-review and study protocol
The Züri Can study: Can regulated cannabis sales promote lower-risk cannabis use? Mini-review and study protocol Open
The study will contribute to a better understanding of the impact of different cannabis distribution models on cannabis use patterns and related health outcomes. The results are expected to assist Swiss and international policy makers in d…
View article: Decoding of resting-state using task-based multivariate pattern analysis supports the Incentive-Sensitization Theory in nicotine use disorder
Decoding of resting-state using task-based multivariate pattern analysis supports the Incentive-Sensitization Theory in nicotine use disorder Open
Background The Incentive-Sensitization Theory postulates that addiction is primarily driven by the sensitization of the brain’s reward system to addictive substances, such as nicotine. According to this theory, exposure to such substances …
View article: Associations between behavioral and neuronal changes in self-referential processing following a single, moderate dose of psilocybin in depressed patients
Associations between behavioral and neuronal changes in self-referential processing following a single, moderate dose of psilocybin in depressed patients Open
View article: The Swiss Brain Health Plan 2023–2033
The Swiss Brain Health Plan 2023–2033 Open
The brain and its health are essential for our (physical mental, social, and spiritual) wellbeing, for being able to realize our potential as individuals, and also for a fair, well-functioning, and productive society. However, today the wo…
View article: Medizinische Behandlungen mit Psychedelika
Medizinische Behandlungen mit Psychedelika Open
View article: La psychothérapie assistée par psychédéliques
La psychothérapie assistée par psychédéliques Open
La psychothérapie assistée par psychédéliques
View article: Investigating neural correlates of self-reported impulsivity: a dimensional structure-symptom approach across psychiatric diagnoses
Investigating neural correlates of self-reported impulsivity: a dimensional structure-symptom approach across psychiatric diagnoses Open
View article: Neural correlates of an altered state of consciousness in patients with alcohol use disorder
Neural correlates of an altered state of consciousness in patients with alcohol use disorder Open
View article: Transdiagnostic brain correlates of self-reported trait impulsivity: A dimensional structure-symptom investigation
Transdiagnostic brain correlates of self-reported trait impulsivity: A dimensional structure-symptom investigation Open
Impulsivity transcends psychiatric diagnoses and is often related to anhedonia. This ad hoc cross-sectional investigation explored 1) whether self-reported trait impulsivity mapped onto a common structural brain substrate across healthy co…
View article: Züri Can – a pilot project to foster low-risk cannabis use within the novel Swiss regulatory framework
Züri Can – a pilot project to foster low-risk cannabis use within the novel Swiss regulatory framework Open
View article: Cannabis Consumers’ View of Regulated Access to Recreational Cannabis: A Multisite Survey in Switzerland
Cannabis Consumers’ View of Regulated Access to Recreational Cannabis: A Multisite Survey in Switzerland Open
Introduction: There is considerable effort in legalizing recreational use of cannabis globally. The successful implementation of a program of regulated access to recreational cannabis (PRAC) depends on the consumers’ engagement. The aim of…
View article: Does serotonin system stimulation increase pro-social behavior? A comparative pharmacological neuroscientific study in healthy humans
Does serotonin system stimulation increase pro-social behavior? A comparative pharmacological neuroscientific study in healthy humans Open
View article: Accumbal-thalamic connectivity and associated glutamate alterations in human cocaine craving: A state-dependent rs-fMRI and 1H-MRS study
Accumbal-thalamic connectivity and associated glutamate alterations in human cocaine craving: A state-dependent rs-fMRI and 1H-MRS study Open
View article: Supplementary Material for: Cannabis consumers' view of regulated access to recreational cannabis – a multi-site survey in [name withheld for review]
Supplementary Material for: Cannabis consumers' view of regulated access to recreational cannabis – a multi-site survey in [name withheld for review] Open
Introduction. There is considerable effort in legalizing recreational use of cannabis globally. The successful implementation of a program of regulated access to recreational cannabis (PRAC) depends on the consumers' engagement. The aim of…
View article: N-acetylcysteine modulates prefrontal response to cocaine cues
N-acetylcysteine modulates prefrontal response to cocaine cues Open
View article: Simplifying cannabis use disorder screening: exploring motives for cannabis use and demographic factors
Simplifying cannabis use disorder screening: exploring motives for cannabis use and demographic factors Open
View article: Negative symptoms in alcohol use disorder: A pilot study applying the two-factor model of negative symptoms to patients with alcohol use disorder
Negative symptoms in alcohol use disorder: A pilot study applying the two-factor model of negative symptoms to patients with alcohol use disorder Open
Background and aims Alcohol Use Disorder (AUD) is characterized by a reduction in goal-directed behavior, with alcohol use taking precedence over other areas of life. These features in AUD resemble negative symptoms in schizophrenia, espec…
View article: Funktionelle Unterschiede in der Verarbeitung akustischer Information im Hippokampus bei professionellen Musikern und musikalischen Laien ein Modell für Neuroplastizität
Funktionelle Unterschiede in der Verarbeitung akustischer Information im Hippokampus bei professionellen Musikern und musikalischen Laien ein Modell für Neuroplastizität Open
View article: Thalamic volume and functional connectivity are associated with nicotine dependence severity and craving
Thalamic volume and functional connectivity are associated with nicotine dependence severity and craving Open
Tobacco smoking is associated with deleterious health outcomes. Most smokers want to quit smoking, yet relapse rates are high. Understanding neural differences associated with tobacco use may help generate novel treatment options. Several …
View article: Individual differences in successful self-regulation of the dopaminergic midbrain
Individual differences in successful self-regulation of the dopaminergic midbrain Open
The dopaminergic midbrain is associated with reinforcement learning, motivation and decision-making – functions often disturbed in neuropsychiatric disorders. Previous research has shown that dopaminergic midbrain activity can be endogenou…
View article: Investigating cue-reactivity as biomarker for treatment success in psilocybin-assisted therapy for alcohol use disorder
Investigating cue-reactivity as biomarker for treatment success in psilocybin-assisted therapy for alcohol use disorder Open
View article: Use of psychotropic substances among elite athletes – a narrative review
Use of psychotropic substances among elite athletes – a narrative review Open
BACKGROUND AND AIMS Elite athletes may use psychotropic substances for recreational reasons, (perceived) performance enhancement or self-medication. Causes can overlap. For athletes, substance use may be associated with various medical and…
View article: Psychedelic-Assisted Therapy for Substance Use Disorders and Potential Mechanisms of Action
Psychedelic-Assisted Therapy for Substance Use Disorders and Potential Mechanisms of Action Open
View article: Pharmacotherapy for Cocaine Use Disorders
Pharmacotherapy for Cocaine Use Disorders Open
View article: Neural mapping of anhedonia across psychiatric diagnoses: A transdiagnostic neuroimaging analysis
Neural mapping of anhedonia across psychiatric diagnoses: A transdiagnostic neuroimaging analysis Open
View article: Aberrant striatal coupling with default mode and central executive network relates to self-reported avolition and anhedonia in schizophrenia
Aberrant striatal coupling with default mode and central executive network relates to self-reported avolition and anhedonia in schizophrenia Open