Explanipedia

Die Bedeutung von Sarkopenie für die immunvermittelte Toxizität bei Patienten mit malignem Melanom unter einer Immuncheckpoint-Inhibition Open

Christian Holtorf, Miriam Mengoni, Thomas Tüting, Andreas Wienke, Jan Borggrefe , et al. · 2024

S3 guideline „actinic keratosis and cutaneous squamous cell carcinoma“ – update 2023, part 2: epidemiology and etiology, diagnostics, surgical and systemic treatment of cutaneous squamous cell carcinoma (cSCC), surveillance and prevention Open

Ulrike Leiter, Markus V. Heppt, Theresa Steeb, Mareike Alter, Teresa Amaral , et al. · 2023

Summary Actinic keratosis (AK) are common lesions in light‐skinned individuals that can potentially progress to cutaneous squamous cell carcinoma (cSCC). Both conditions may be associated with significant morbidity and constitute a major d…

S3‐Leitlinie “Aktinische Keratose und Plattenepithelkarzinom der Haut“ – Update 2023, Teil 1: Therapie der aktinischen Keratose, Morbus Bowen, Cheilitis actinica, berufsbedingte Erkrankung und Versorgungsstrukturen Open

Markus V. Heppt, Ulrike Leiter, Theresa Steeb, Mareike Alter, Teresa Amaral , et al. · 2023

Zusammenfassung Aktinische Keratosen (AK) sind häufige Hautveränderungen bei hellhäutigen Menschen mit dem Potenzial, in ein kutanes Plattenepithelkarzinom (PEK) überzugehen. Beide Erkrankungen können mit erheblicher Morbidität verbunden s…

S3 guideline „actinic keratosis and cutaneous squamous cell carcinoma“– update 2023, part 1: treatment of actinic keratosis, actinic cheilitis, cutaneous squamous cell carcinoma in situ (Bowen's disease), occupational disease and structures of care Open

Markus V. Heppt, Ulrike Leiter, Theresa Steeb, Mareike Alter, Teresa Amaral , et al. · 2023

Summary Actinic keratosis (AK) are common lesions in light‐skinned individuals that can potentially progress to cutaneous squamous cell carcinoma (cSCC). Both conditions may be associated with significant morbidity and constitute a major d…

Eosinophile Fasziitis als seltene Nebenwirkung unter PD1‐Inhibitor Therapie Open

Yenny Angela, Samaneh Ghashang Khoshandam, Mareike Alter, Ralf Gutzmer · 2023

Bei einem 74-jährigen Mann wurde bei Stadium IIIC eines malignen Melanoms eine adjuvante Therapie mittels PD1-Inhibitor (Nivolumab) initiiert. Nach 6-monatiger Behandlung klagte der Patient über zunehmende Muskelschmerzen v. a. in beiden U…

German S3 guideline “actinic keratosis and cutaneous squamous cell carcinoma” – Long version of the update 2023 Open

Ulrike Leiter, Markus V. Heppt, Theresa Steeb, Mareike Alter, Teresa Amaral , et al. · 2023

Actinic keratosis (AK) are common lesions in light-skinned individuals that can potentially progress to cutaneous squamous cell carcinoma (cSCC). Both conditions may be associated with significant morbidity and constitute a major disease b…

„Axilläres‐Netz‐Syndrom“ als Komplikation der axillären Schildwächterlymphknotenoperation Open

Yenny Angela, Tanja Krömer‐Olbrisch, Ralf Gutzmer, Mareike Alter · 2022

Axillary web syndrome as complication of axillary sentinel lymph node surgery Open

Yenny Angela, Tanja Krömer‐Olbrisch, Ralf Gutzmer, Mareike Alter · 2022

Axillary web syndrome as complication of axillary sentinel lymph node surgeryDear Editors, axillary web syndrome (AWS), first described in 2001 [1], is a complication of sentinel lymph node biopsy (SLNB).Arising after the procedure, it is …

Long-Term Management of Advanced Basal Cell Carcinoma: Current Challenges and Future Perspectives Open

Markus V. Heppt, Christoffer Gebhardt, Jessica C. Hassel, Mareike Alter, Ralf Gutzmer , et al. · 2022

The first-line therapy for locally advanced basal cell carcinoma (laBCC) is Hedgehog pathway inhibitors (HHIs), as they achieve good efficacy and duration of response. However, toxicity in the course of long-term treatment may lead to a de…

Surveillance of patients with conjunctival melanoma in German-speaking countries: A multinational survey of the German dermatologic cooperative oncology group Open

Anja Wessely, Theresa Steeb, Carola Berking, Max Schlaak, Markus V. Heppt , et al. · 2020

Patterns of care and follow-up care of patients with uveal melanoma in German-speaking countries: a multinational survey of the German Dermatologic Cooperative Oncology Group (DeCOG) Open

Theresa Steeb, Anja Wessely, Mareike Alter, Christiane Bayerl, Armin Bender , et al. · 2020

Superior skin cancer classification by the combination of human and artificial intelligence Open

Achim Hekler, Jochen Utikal, Alexander Enk, Axel Hauschild, Michael Weichenthal , et al. · 2019

Regarding the multiclass task, the combination of man and machine achieved an accuracy of 82.95%. This was 1.36% higher than the best of the two individual classifiers (81.59% achieved by the CNN). Owing to the class imbalance in the binar…

Systematic outperformance of 112 dermatologists in multiclass skin cancer image classification by convolutional neural networks Open

Roman C. Maron, Michael Weichenthal, Jochen Utikal, Achim Hekler, Carola Berking , et al. · 2019

Our findings show that automated classification of dermoscopic melanoma and nevi images is extendable to a multiclass classification problem, thus better reflecting clinical differential diagnoses, while still outperforming dermatologists …

Current diagnosis and treatment of basal cell carcinoma Open

Mareike Alter, Uwe Hillen, Ulrike Leiter, Michael Sachse, Ralf Gutzmer · 2015

Summary Basal cell carcinoma represents is most common tumor in fair‐skinned individuals. In Germany, age‐standardized incidence rates are 63 (women) and 80 (men) per 100,000 population per year. Early lesions may be difficult to diagnose …

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