Mareike Witte
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View article: Primary Cutaneous Gamma-Delta T-Cell Lymphoma With Long-Term Indolent Clinical Course Initially Mimicking Lupus Erythematosus Profundus
Primary Cutaneous Gamma-Delta T-Cell Lymphoma With Long-Term Indolent Clinical Course Initially Mimicking Lupus Erythematosus Profundus Open
Primary Cutaneous Gamma-Delta (γδ) T-Cell Lymphoma (PCGDTCL) is a rare primary cutaneous lymphoma of aggressive nature. Only a few cases with an initially indolent course over years have been published. PCGDTCL can mimic diseases with beni…
View article: Polymorphisms in the Mitochondrial Genome Are Associated With Bullous Pemphigoid in Germans
Polymorphisms in the Mitochondrial Genome Are Associated With Bullous Pemphigoid in Germans Open
Bullous pemphigoid (BP) is the most prevalent autoimmune skin blistering disease and is characterized by the generation of autoantibodies against the hemidesmosomal proteins BP180 (type XVII collagen) and BP230. Most intriguingly, BP is di…
View article: Genetics and Omics Analysis of Autoimmune Skin Blistering Diseases
Genetics and Omics Analysis of Autoimmune Skin Blistering Diseases Open
Autoimmune blistering diseases (AIBDs) of the skin are characterized by autoantibodies against different intra-/extracellular structures within the epidermis and at the basement membrane zone (BMZ). Binding of the antibodies to their targe…
View article: Proinflammatory Cytokine Gene Polymorphisms in Bullous Pemphigoid
Proinflammatory Cytokine Gene Polymorphisms in Bullous Pemphigoid Open
Bullous pemphigoid (BP) is a rare autoimmune skin blistering disease, characterized by the presence of autoantibodies against hemidesmosomal autoantigens. Cytokine expression is altered in BP patients, and several of these differently expr…
View article: Diagnosis of Autoimmune Blistering Diseases
Diagnosis of Autoimmune Blistering Diseases Open
Autoimmune skin blistering diseases (AIBD) are characterized by autoantibodies that are directed against structural proteins in the skin and adjacent mucous membranes. Some clinical signs are typical for a specific AIBD, however, correct d…
View article: Iatrogenic hypospadias classification: A new way to classify hypospadias caused by long‐term catheterization
Iatrogenic hypospadias classification: A new way to classify hypospadias caused by long‐term catheterization Open
None declared. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author fo…
View article: Regulatory T Cells Suppress Inflammation and Blistering in Pemphigoid Diseases
Regulatory T Cells Suppress Inflammation and Blistering in Pemphigoid Diseases Open
Regulatory T cells (Tregs) are well known for their modulatory functions in adaptive immunity. Through regulation of T cell functions, Tregs have also been demonstrated to indirectly curb myeloid cell-driven inflammation. However, direct e…
View article: Dissecting genetics of cutaneous miRNA in a mouse model of an autoimmune blistering disease
Dissecting genetics of cutaneous miRNA in a mouse model of an autoimmune blistering disease Open
The murine advanced intercross line allowed us to identify the genetic loci regulating multiple miRNA in skin. The recurrence of trans-eQTL and epistasis suggest that cutaneous miRNAs are regulated by yet an unexplored complex gene network…
View article: Additional file 1: Figure S1. of Dissecting genetics of cutaneous miRNA in a mouse model of an autoimmune blistering disease
Additional file 1: Figure S1. of Dissecting genetics of cutaneous miRNA in a mouse model of an autoimmune blistering disease Open
Flowchart describing the workflow of analysis. The flowchart provides an overview of the analysis performed for understanding regulation of miRNAs and their contribution to the disease phenotype. Figure S2 Interaction network accessed via …