Marek Józefowicz
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View article: The role of solute polarizability and microenvironment in the spectroscopic behaviour of the local anesthetic drug - bupivacaine
The role of solute polarizability and microenvironment in the spectroscopic behaviour of the local anesthetic drug - bupivacaine Open
The solvent dependent ground- and excited-state photophysical and photochemical properties of the local anesthetic drug – bupivacaine (BUP) – have been studied using a steady-state spectroscopic technique. The Kamlet-Taft solvent scale was…
View article: The Role of Solute Polarizability and Microenvironment in the Spectroscopic Behaviour of the Local Anesthetic Drug - Bupivacaine
The Role of Solute Polarizability and Microenvironment in the Spectroscopic Behaviour of the Local Anesthetic Drug - Bupivacaine Open
View article: The Role of Solute Polarizability and Microenvironment in the Spectroscopic Behaviour of the Local Anesthetic Drug - Bupivacaine
The Role of Solute Polarizability and Microenvironment in the Spectroscopic Behaviour of the Local Anesthetic Drug - Bupivacaine Open
View article: Transport Mechanism of Paracetamol (Acetaminophen) in Polyurethane Nanocomposite Hydrogel Patches—Cloisite® 30B Influence on the Drug Release and Swelling Processes
Transport Mechanism of Paracetamol (Acetaminophen) in Polyurethane Nanocomposite Hydrogel Patches—Cloisite® 30B Influence on the Drug Release and Swelling Processes Open
This article describes the swelling and release mechanisms of paracetamol in polyurethane nanocomposite hydrogels containing Cloisite® 30B (organically modified montmorillonite). The transport mechanism, swelling and release processes of t…
View article: Spectroscopic Studies on the Supramolecular Interactions of Methyl Benzoate Derivatives with P-Sulfocalix[6]Arene Macrocycles
Spectroscopic Studies on the Supramolecular Interactions of Methyl Benzoate Derivatives with P-Sulfocalix[6]Arene Macrocycles Open
View article: Preparation and Characterization of Indomethacin Supramolecular Systems with β-Cyclodextrin in Order to Estimate Photostability Improvement
Preparation and Characterization of Indomethacin Supramolecular Systems with β-Cyclodextrin in Order to Estimate Photostability Improvement Open
Cyclodextrins have found wide application in contemporary chemistry, pharmacy and medicine. Because of their unique properties, cyclodextrins are constantly used in research on solubility or stability improvement, as well as other physicoc…
View article: Insight into Molecular Interactions of Two Methyl Benzoate Derivatives with Bovine Serum Albumin
Insight into Molecular Interactions of Two Methyl Benzoate Derivatives with Bovine Serum Albumin Open
The nature and mechanisms of interaction between two selected methyl benzoate derivatives (methyl o-methoxy p-methylaminobenzoate–I and methyl o-hydroxy p-methylaminobenzoate–II) and model transport protein bovine serum albumin (BSA) was s…
View article: The Role of Hydrogen Bonding in Paracetamol–Solvent and Paracetamol–Hydrogel Matrix Interactions
The Role of Hydrogen Bonding in Paracetamol–Solvent and Paracetamol–Hydrogel Matrix Interactions Open
The photophysical and photochemical properties of antipyretic drug – paracetamol (PAR) and its two analogs with different substituents (acetanilide (ACT) and N-ethylaniline (NEA)) in 14 solvents of different polarity were investigated by t…
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Plenary lectures Open
Experimental approaches to study electrostatic effects in biomolecular processes include investigation of their dependence on the ionic strength of the medium in which they occur.One interesting class of biomolecular processes subject to s…
View article: Transport of paracetamol in swellable and relaxing polyurethane nanocomposite hydrogels
Transport of paracetamol in swellable and relaxing polyurethane nanocomposite hydrogels Open
Polyurethane hydrogels are potentially attractive materials for biomedical applications. They are able to absorb large amount of water, biological fluids or active substances, and thus, they have potential to be used as absorbents or wound…
View article: The<i>trans</i>/<i>cis</i>photoisomerization in hydrogen bonded complexes with stability controlled by substituent effects: 3-(6-aminopyridin-3-yl)acrylate case study
The<i>trans</i>/<i>cis</i>photoisomerization in hydrogen bonded complexes with stability controlled by substituent effects: 3-(6-aminopyridin-3-yl)acrylate case study Open
The association of aminopyridine-based acrylic acid and its salt was studied by NMR titration experiments.
View article: Nanosize effect of clay mineral nanoparticles on the drug diffusion processes in polyurethane nanocomposite hydrogels
Nanosize effect of clay mineral nanoparticles on the drug diffusion processes in polyurethane nanocomposite hydrogels Open
Studies of swelling and release of naproxen sodium (NAP) solution by polyurethane nanocomposite hydrogels containing Cloisite® 30B (organically modified montmorillonite (OMMT)) have been performed. Polyurethane nanocomposite hydrogels are …
View article: Spectrophotometric studies of marine surfactants in the southern Baltic Sea
Spectrophotometric studies of marine surfactants in the southern Baltic Sea Open
It is well known that surfactants in the southern Baltic Sea constitute the organic matter from riverine waters discharges as well as the secondary degradation products of marine phytoplankton excretion. They reach the surface microlayer b…
View article: Spectrofluorometric characteristics of fluorescent dissolved organic matter in a surface microlayer in the Southern Baltic coastal waters
Spectrofluorometric characteristics of fluorescent dissolved organic matter in a surface microlayer in the Southern Baltic coastal waters Open
This paper presents results of characterization of Dissolved Organic Matter (DOM) using fluorescence spectroscopy in the surface microlayers (SML) and subsurface layers (SS) in the Baltic Sea. Samples for spectroscopic measurements were co…