Marek Kulus
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View article: Methodology for the Development of the Allergic Rhinitis and Its Impact on Asthma ( <scp>ARIA</scp> )‐EAACI 2024–2025 Guidelines: From Evidence‐to‐Decision Frameworks to Digitalised Shared Decision‐Making Algorithms
Methodology for the Development of the Allergic Rhinitis and Its Impact on Asthma ( <span>ARIA</span> )‐EAACI 2024–2025 Guidelines: From Evidence‐to‐Decision Frameworks to Digitalised Shared Decision‐Making Algorithms Open
The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines produced their first edition in 1999, with subsequent revisions in 2008, 2010, 2016 and 2019. A new iteration of ARIA—ARIA 2024–2025—in collaboration with EAACI is currently …
View article: Decoding Early Clues: Immune Mechanisms, Prevention, Diagnosis, and Treatment of IgE-Mediated Peanut and Tree Nut Allergy in Children
Decoding Early Clues: Immune Mechanisms, Prevention, Diagnosis, and Treatment of IgE-Mediated Peanut and Tree Nut Allergy in Children Open
The rising prevalence of food allergies, particularly to peanuts and tree nuts, poses significant challenges for pediatric health worldwide. These allergens are among the leading causes of severe allergic reactions, including anaphylaxis, …
View article: Daily digital biomarkers in the follow-up and clustering of patients with asthma
Daily digital biomarkers in the follow-up and clustering of patients with asthma Open
Levels of digital biomarkers reflect asthma control patterns and might be used to monitor patients with asthma.
View article: Efficacy of cashew nut protein immunotherapy: protocol for a single-centre randomised controlled trial in a Polish paediatric population
Efficacy of cashew nut protein immunotherapy: protocol for a single-centre randomised controlled trial in a Polish paediatric population Open
Introduction The prevalence of food allergies, particularly IgE-mediated allergies, is rising in developed countries, with cashew nut allergy emerging as a significant public health concern due to its potential for severe anaphylaxis and f…
View article: Milk ladder and oral immunotherapy in IgE-mediated cow’s milk allergy
Milk ladder and oral immunotherapy in IgE-mediated cow’s milk allergy Open
IgE-mediated cow’s milk allergy is a significant clinical problem. It may be persistent in a large percentage of children. This allergy is associated with restrictive diet, limitations in social activities and anxiety arising from the fear…
View article: Diagnostic Evaluation and Clinical Findings in Children With Persistent Tachypnea of Infancy/Neuroendocrine Cell Hyperplasia of Infancy
Diagnostic Evaluation and Clinical Findings in Children With Persistent Tachypnea of Infancy/Neuroendocrine Cell Hyperplasia of Infancy Open
Diagnosis of PTI/NEHI relies on clinical symptoms and HRCT imaging results, with lung biopsies less commonly performed. Differences exist among countries regarding the number and type of investigations. A need exists for guidelines that wi…
View article: The High Levels of Soluble Receptors for Tumor Necrosis Factor and Heart Injury in Children with the Pediatric Inflammatory Multisystem Syndrome Associated with Coronavirus Infection: Is This Just a Coincidence? A Proof-of-Concept Study
The High Levels of Soluble Receptors for Tumor Necrosis Factor and Heart Injury in Children with the Pediatric Inflammatory Multisystem Syndrome Associated with Coronavirus Infection: Is This Just a Coincidence? A Proof-of-Concept Study Open
(1) Pediatric inflammatory multisystem syndrome (PIMS) is a relatively rare complication of coronavirus disease (COVID-19). So far, it is unclear why COVID-19 in children has usually mild or asymptomatic courses, whereas PIMS, which develo…
View article: Guidelines for the diagnosis and management of asthmaby the Polish Society of Allergology, Polish Society of LungDiseases, Polish Society of Pediatric Pneumology, and PolishSociety of Family Medicine (STAN4T)
Guidelines for the diagnosis and management of asthmaby the Polish Society of Allergology, Polish Society of LungDiseases, Polish Society of Pediatric Pneumology, and PolishSociety of Family Medicine (STAN4T) Open
The updated and enhanced guidelines for the diagnosis and treatment of asthma in children and adults were developed by expert physicians from four Polish medical societies, using the GRADE methodology. The guidelines provide a concise and …
View article: 2024 Update on Position Statement by Experts from the Polish Society of Allergology and the Polish Respiratory Society on the Evaluation of Efficacy and Effectiveness of Single Inhaler Triple Therapies in Asthma Treatment
2024 Update on Position Statement by Experts from the Polish Society of Allergology and the Polish Respiratory Society on the Evaluation of Efficacy and Effectiveness of Single Inhaler Triple Therapies in Asthma Treatment Open
Medication non-adherence remains a substantial obstacle in asthma care, prompting the exploration of novel therapeutic modalities that prioritize rapid symptom relief, anti-inflammatory activity, and facilitate patients’ compliance. This t…
View article: Peanut Allergy in Children—Is Prevention Better than Cure?
Peanut Allergy in Children—Is Prevention Better than Cure? Open
Peanut allergy, one of the most frequently occurring allergies, usually starts in childhood and rarely subsides—often persisting throughout adult life. Accidental exposure to peanuts can often result in adverse reactions ranging from mild …
View article: Concurrent validity, cut‐offs and ability to change of patient‐reported outcome measures for rhinitis and asthma in MASK‐air<sup>®</sup>
Concurrent validity, cut‐offs and ability to change of patient‐reported outcome measures for rhinitis and asthma in MASK‐air<sup>®</sup> Open
Patient‐reported outcome measures (PROMs) are used to assess a patient's health status at a particular point in time. They are essential in the development of person‐centred care. This paper reviews studies performed on PROMs for assessing…
View article: Efficacy and safety of low-dose sesame oral immunotherapy in paediatric patients: a protocol for a single-centre, randomised controlled trial
Efficacy and safety of low-dose sesame oral immunotherapy in paediatric patients: a protocol for a single-centre, randomised controlled trial Open
Introduction Sesame allergy, though with low prevalence, can result in severe, potentially life-threatening reactions and poses challenges in allergen avoidance due to hidden sources. In the majority of patients, sesame allergy persists an…
View article: 2024 Update on Position Statement by Experts from the Polish Society of Allergology and the Polish Respiratory Society on the Evaluation of Efficacy and Effectiveness of Single Inhaler Triple Therapies in Asthma Treatment
2024 Update on Position Statement by Experts from the Polish Society of Allergology and the Polish Respiratory Society on the Evaluation of Efficacy and Effectiveness of Single Inhaler Triple Therapies in Asthma Treatment Open
Medication non-adherence remains a substantial obstacle in asthma care, prompting the exploration of novel therapeutic modalities that prioritize rapid symptom relief, anti-inflammatory activity and facilitate patients’ compliance. This ta…
View article: Is Component-Specific Antibody Testing Sufficient to Replace the Oral Food Challenge in the Diagnostics of Peanut-Sensitized Children? A Proof-of-Concept Study
Is Component-Specific Antibody Testing Sufficient to Replace the Oral Food Challenge in the Diagnostics of Peanut-Sensitized Children? A Proof-of-Concept Study Open
(1) Peanut allergy is associated with high risk of anaphylaxis which could be prevented by oral immunotherapy. Patients eligible for immunotherapy are selected on the basis of a food challenge, although currently the assessment of antibodi…
View article: Poor Rhinitis and Asthma Control Is Associated With Decreased Health-Related Quality of Life and Utilities: A MASK-air Study
Poor Rhinitis and Asthma Control Is Associated With Decreased Health-Related Quality of Life and Utilities: A MASK-air Study Open
Poor AR or asthma control are associated with reduced quality of life. The estimates obtained from mobile health data may provide valuable insights for health technology assessment studies.
View article: Asthma and rhinitis control in adolescents and young adults: A real‐world <scp>MASK</scp> ‐air study
Asthma and rhinitis control in adolescents and young adults: A real‐world <span>MASK</span> ‐air study Open
Background In allergic rhinitis and asthma, adolescents and young adult patients are likely to differ from older patients. We compared adolescents, young adults and adults on symptoms, control levels, and medication adherence. Methods In a…
View article: IP-10 for the Diagnosis and Treatment Monitoring of Tuberculosis in Children
IP-10 for the Diagnosis and Treatment Monitoring of Tuberculosis in Children Open
Purpose: To determine the utility of interferon-gamma-inducible protein 10 (IP-10) for identifying active tuberculosis (TB) and TB infection (TBI) in children in BCG-vaccinated populations, establish its diagnostic performance characterist…
View article: Current trends in peanut allergy immunotherapy: a review
Current trends in peanut allergy immunotherapy: a review Open
Peanut allergy (PA) poses significant clinical challenges due to its potentially life-threatening nature and increasing prevalence, particularly in children. Strict avoidance is difficult due to the widespread presence of peanuts in variou…
View article: Development of peanut, sesame and tree nut allergy in Polish children at high risk of food allergy: a protocol for a cross-sectional study
Development of peanut, sesame and tree nut allergy in Polish children at high risk of food allergy: a protocol for a cross-sectional study Open
Introduction Peanut allergies cause serious health problems worldwide. A strong finding has shown that the early introduction of peanuts into the diet of infants at high risk of food allergy reduces the prevalence of peanut allergy. Allerg…
View article: <scp>UCRAID</scp> (Ukrainian Citizen and refugee electronic support in Respiratory diseases, Allergy, Immunology and Dermatology) action plan
<span>UCRAID</span> (Ukrainian Citizen and refugee electronic support in Respiratory diseases, Allergy, Immunology and Dermatology) action plan Open
Eight million Ukrainians have taken refuge in the European Union. Many have asthma and/or allergic rhinitis and/or urticaria, and around 100,000 may have a severe disease. Cultural and language barriers are a major obstacle to appropriate …
View article: Patient‐centered digital biomarkers for allergic respiratory diseases and asthma: The <scp>ARIA‐EAACI</scp> approach – ARIA‐EAACI Task Force Report
Patient‐centered digital biomarkers for allergic respiratory diseases and asthma: The <span>ARIA‐EAACI</span> approach – ARIA‐EAACI Task Force Report Open
Biomarkers for the diagnosis, treatment and follow‐up of patients with rhinitis and/or asthma are urgently needed. Although some biologic biomarkers exist in specialist care for asthma, they cannot be largely used in primary care. There ar…
View article: IP-10 for the diagnosis and treatment monitoring of tuberculosis in children.
IP-10 for the diagnosis and treatment monitoring of tuberculosis in children. Open
Purpose: To determine the utility of interferon-gamma-inducible protein 10 (IP-10) for identifying active tuberculosis (TB) and latent TB infection (LTBI) in children in BCG-vaccinated population, establish its diagnostic performance chara…
View article: Prevalence of major food allergens in skincare products for atopic dermatitis
Prevalence of major food allergens in skincare products for atopic dermatitis Open
Our analysis revealed that major food allergens are prevalent in skincare products for eczema. Applying skincare products containing food derivatives on affected and inflamed skin can promote percutaneous sensitisation. Therefore, clinicia…
View article: Oesophageal achalasia in an 11-year-old patient with persistent respiratory symptoms and suspected bronchial asthma
Oesophageal achalasia in an 11-year-old patient with persistent respiratory symptoms and suspected bronchial asthma Open
Oesophageal achalasia is a disease characterized by the inability of the lower oesophageal sphincter (LOS) to relax, which results in persistent contraction and the lack of peristaltic movement in the oesophageal body. It is a rare conditi…
View article: Diagnostic accuracy of peripheral lung function measurements in paediatric asthma control assessment: a pilot study
Diagnostic accuracy of peripheral lung function measurements in paediatric asthma control assessment: a pilot study Open
LCI, Sacin and Fres had the highest discriminative capacity for distinguishing children with controlled and uncontrolled asthma among all evaluated peripheral airways measures. Discrepancies in the performance (i.e. sensitivity and specifi…
View article: Guidelines for asthma diagnosis and treatment Polish Society of Allergology, Polish Society of Lung Diseases and Polish Society of Family Medicine (STAN3T)
Guidelines for asthma diagnosis and treatment Polish Society of Allergology, Polish Society of Lung Diseases and Polish Society of Family Medicine (STAN3T) Open
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Pawliczak R, Emeryk A, Kupczyk M, Chorostowska-Wynimko J, Kuna P, Kulus M. Guidelines for asthma diagnosis and treatment Polish Society of Allergology, Polis…
View article: Sensitization to nut allergens in children with food allergyand other atopic diseases – just a coexistence?
Sensitization to nut allergens in children with food allergyand other atopic diseases – just a coexistence? Open
The analysis of sensitization patterns may help to identify patients with an increased risk, and gives the opportunity to introduce more effective prophylaxis. However, since even the first exposure to nuts may be sufficient to trigger the…
View article: Decision-making algorithms for asthma diagnosis and treatment – a STAN3T guidelines amendment
Decision-making algorithms for asthma diagnosis and treatment – a STAN3T guidelines amendment Open
AMA Majak P, Pawliczak R, Kulus M. Decision-making algorithms for asthma diagnosis and treatment – a STAN3T guidelines amendment. Alergologia Polska - Polish Journal of Allergology. 2023;10(2):71-76. doi:10.5114/pja.2023.129111. APA Majak,…