Marek Murawski
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View article: High-Intensity Focused Ultrasound (HIFU) Treatment of Vulvar Lichen Sclerosus
High-Intensity Focused Ultrasound (HIFU) Treatment of Vulvar Lichen Sclerosus Open
Vulvar lichen sclerosus (VLS) is a chronic, recurrent dermatosis predominantly affecting postmenopausal women. It is characterized by atrophic and sclerotic changes in the vulvar skin, often causing severe discomfort and functional impairm…
View article: Sentinel Node Biopsy Using Two Concurrent Labeling Techniques (Radioactive Tracer With/Without Blue Dye vs. Indocyanin Green-ICG) in Early-Stage Endometrial Cancer Patients (TESLA–1): A Prospective Observational Study CEEGOG EX-02
Sentinel Node Biopsy Using Two Concurrent Labeling Techniques (Radioactive Tracer With/Without Blue Dye vs. Indocyanin Green-ICG) in Early-Stage Endometrial Cancer Patients (TESLA–1): A Prospective Observational Study CEEGOG EX-02 Open
Background: While sentinel lymph node (SLN) biopsy has been integrated into international guidelines for endometrial cancer, a standardized technique is still lacking. This study addresses whether the concurrent use of two tracers, technet…
View article: Male Hormonal Contraception—Current Stage of Knowledge
Male Hormonal Contraception—Current Stage of Knowledge Open
Male hormonal contraception has been the focus of extensive research efforts aimed at identifying effective and reversible methods for male fertility control. This review summarizes the current state of knowledge, key achievements, and fut…
View article: Evaluation of the effect of the type of hysterectomy on the incidence of stress urinary incontinence
Evaluation of the effect of the type of hysterectomy on the incidence of stress urinary incontinence Open
Hysterectomy is performed by various surgical methods: abdominal, vaginal, laparoscopic, or robotic, and with different extents: supracervical, total, or radical. Scientific reports indicate that hysterectomy is a risk factor for stress ur…
View article: Polycystic Ovary Syndrome and Eating Disorders—A Literature Review
Polycystic Ovary Syndrome and Eating Disorders—A Literature Review Open
Polycystic ovary syndrome (PCOS) is a complex endocrine disorder that affects women of reproductive age and is characterized by hyperandrogenism, ovulatory dysfunction and polycystic ovarian morphology. PCOS is often associated with hormon…
View article: Comparative Analysis of Primary Ovarian Cancer Cells and Established Cell Lines as a New Tool for Studies on Ovarian Cancer Cell Complexity
Comparative Analysis of Primary Ovarian Cancer Cells and Established Cell Lines as a New Tool for Studies on Ovarian Cancer Cell Complexity Open
Primary cancer cells reflect the genetic background and phenotype of a tumor. Immortalized cells with higher proliferation activity have an advantage over primary cells. The aim of the study was to immortalize the primary ovarian cancer (O…
View article: Impact of Bisphosphonate Therapy on Oral Health in Patients with Breast and Prostate Cancer and Bone Metastases: A Comprehensive Study
Impact of Bisphosphonate Therapy on Oral Health in Patients with Breast and Prostate Cancer and Bone Metastases: A Comprehensive Study Open
This study investigates the impact of bisphosphonate therapy on the stomatognathic system in 80 patients with cancer of the breast and prostate with bone metastases. Bisphosphonates are integral for managing skeletal complications in these…
View article: Complexity of the Genetic Background of Oncogenesis in Ovarian Cancer—Genetic Instability and Clinical Implications
Complexity of the Genetic Background of Oncogenesis in Ovarian Cancer—Genetic Instability and Clinical Implications Open
Ovarian cancer is a leading cause of death among women with gynecological cancers, and is often diagnosed at advanced stages, leading to poor outcomes. This review explores genetic aspects of high-grade serous, endometrioid, and clear-cell…
View article: Mesenchymal Stem Cell Microvesicles from Adipose Tissue: Unraveling Their Impact on Primary Ovarian Cancer Cells and Their Therapeutic Opportunities
Mesenchymal Stem Cell Microvesicles from Adipose Tissue: Unraveling Their Impact on Primary Ovarian Cancer Cells and Their Therapeutic Opportunities Open
Mesenchymal stem cells (MSCs) and their derivatives can be promising tools in oncology including ovarian cancer treatment. This study aimed to determine the effect of HATMSC2-MVs (microvesicles derived from human immortalized mesenchymal s…
View article: Prognostic Role of Prolactin-Induced Protein (PIP) in Breast Cancer
Prognostic Role of Prolactin-Induced Protein (PIP) in Breast Cancer Open
Prolactin-inducible protein (PIP), also referred to as gross cystic disease fluid protein 15 (GCDFP-15), has been a trending topic in recent years due to its potential role as a specific marker in breast cancer. PIP binds to aquaporin-5 (A…
View article: An unusual coincidence of giant cervical leiomyoma and incidental ovarian granulosa cell tumor: A case report
An unusual coincidence of giant cervical leiomyoma and incidental ovarian granulosa cell tumor: A case report Open
Rationale: Leiomyomas are the most common benign tumors of smooth muscle origin in women. They are most frequently found in the submucosal tissue of the uterine corpus; however, they also occur in other areas of the uterus, including the c…
View article: The Relationship between Restless Legs Syndrome And Pre-Eclampsia: A Mini-Review
The Relationship between Restless Legs Syndrome And Pre-Eclampsia: A Mini-Review Open
Introduction: Pregnancy is associated with significant physiological, psychological, and social changes that affect normal sleep. Sleep disorders whose frequency increases significantly during pregnancy can include restless legs syndrome (…
View article: The effects of chicken egg white cystatin and proteinase inhibitor on cysteine peptidase-like activity in the sera of patients with breast cancer
The effects of chicken egg white cystatin and proteinase inhibitor on cysteine peptidase-like activity in the sera of patients with breast cancer Open
The results suggest that there may be a potential difference between the commercially available cathepsin B and its autogenic analogues found in the serum of cancer patients. The increase in fluorescence induced in the reaction between the…
View article: Significance of Matrix Metalloproteinase 9 Expression as Supporting Marker to Cytokeratin 19 mRNA in Sentinel Lymph Nodes in Breast Cancer Patients
Significance of Matrix Metalloproteinase 9 Expression as Supporting Marker to Cytokeratin 19 mRNA in Sentinel Lymph Nodes in Breast Cancer Patients Open
One-step nucleic acid amplification (OSNA) detects and quantifies, with the use of a polymerase chain reaction, the presence of cytokeratin 19 mRNA in sentinel lymph nodes. The main advantage of the OSNA assay is the avoidance of second su…