Marek Urbanský
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View article: Synthesis of Methylerythritol Phosphate Analogues and Their Evaluation as Alternate Substrates for IspDF and IspE from <i>Agrobacterium tumefaciens</i>
Synthesis of Methylerythritol Phosphate Analogues and Their Evaluation as Alternate Substrates for IspDF and IspE from <i>Agrobacterium tumefaciens</i> Open
The methylerythritol phosphate biosynthetic pathway, found in most Bacteria, some parasitic protists, and plant chloroplasts, converts D-glyceraldehyde phosphate and pyruvate to isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (…
View article: Bornyl diphosphate synthase: Structure and strategy for carbocation manipulation by a terpenoid cyclase
Bornyl diphosphate synthase: Structure and strategy for carbocation manipulation by a terpenoid cyclase Open
The x-ray crystal structure of dimeric (+)-bornyl diphosphate synthase, a metal-requiring monoterpene cyclase from Salvia officinalis , is reported at 2.0-Å resolution. Each monomer contains two α-helical domains: the C-terminal domain cat…