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Computed tomographic myelography of the cranial cervical vertebral column in unaffected Warmblood horses – comparison of transverse vertebral ratios in the flexed and neutral cranial cervical vertebral column Open
Flexion of the cervical vertebral column led to a decrease of the DCAR and an increase of the CDAR at the intervertebral sites in unaffected Warmbloods.
Trigeminal Nerve Asymmetry in Horses With Idiopathic Trigeminal‐Mediated Headshaking: A Retrospective Case‐Control Magnetic Resonance Imaging Study Open
Background Nerve atrophy results in trigeminal nerve (TN) asymmetry detectable by magnetic resonance imaging (MRI) in humans, but similar studies have not been performed in horses with idiopathic trigeminal‐mediated headshaking (ITMHS). Hy…
Computed tomographic myelography of the cranial cervical spine in Warmblood horses with no spinal pathology—Inter‐ and intravertebral ratios and distribution of contrast columns in neutral and flexed cervical spine Open
Background Computed tomographic myelography (CTM) and radiographic myelography (RxM) are diagnostic for extradural spinal cord compression, but knowledge about the contrast distribution in flexion and normal position of nonaffected horses …
Differentiation of equine paranasal sinus cysts and progressive ethmoid haematomas on computed tomographic images Open
Paranasal sinus cysts (PSC) and progressive ethmoid haematomas (PEH) are regularly observed in the paranasal sinus system. Due to their different prognosis and treatment options, differentiation of both lesions prior to surgery on computed…
Spinal ataxia and computed tomography findings in a Poitou donkey affected with congenital occipitoatlantoaxial malformation Open
Summary A 3‐year‐old Poitou donkey was referred for a computed tomography (CT) examination of the cervical spine due to acute deterioration of spinal ataxia. Neurological assessment revealed restricted neck mobility, hypermetria and circum…
Application of the HRE-S to 140 horses with trigeminal-mediated headshaking and the association of clinical signs with diagnosis, therapy, and outcome Open
Background Horses with trigeminal-mediated headshaking (TMHS) exhibit different headshaking patterns (HSPs), electric shock-like jerking, signs of nasal irritation, and painful facial expressions. The History Rest and Exercise Score (HRE-S…
Osteoarthritis of the coxofemoral joint in 24 horses: Evaluation of radiography, ultrasonography, intra‐articular anaesthesia, treatment and outcome Open
Background Few case reports describe equine coxofemoral joint osteoarthritis (CFJOA). Objectives To evaluate diagnostic findings and outcome of horses with CFJOA and to provide a score facilitating radiographic assessment. Study design Ret…
View article: A Missense Mutation in the Collagen Triple Helix of EDA Is Associated with X-Linked Recessive Hypohidrotic Ectodermal Dysplasia in Fleckvieh Cattle
A Missense Mutation in the Collagen Triple Helix of EDA Is Associated with X-Linked Recessive Hypohidrotic Ectodermal Dysplasia in Fleckvieh Cattle Open
Mutations within the ectodysplasin A (EDA) gene have been associated with congenital hypotrichosis and anodontia (HAD/XHED) in humans, mice, dogs and cattle. We identified a three-generation family of Fleckvieh cattle with male calves exhi…
View article: Digitalisation in pre‐purchase examination and prospects for an equine health database in Germany—Results of an online survey among equine veterinarians
Digitalisation in pre‐purchase examination and prospects for an equine health database in Germany—Results of an online survey among equine veterinarians Open
Background Digital recording and storage of health data are becoming increasingly important in the fields of both human and veterinary medicine. There is currently a lack of information on the level of digitalisation among equine veterinar…
Intra- and interobserver agreement study of a grading system for behavioural observation in ridden sports horses Open
Zusammenfassung: Die Einschätzung
Impact of Different Diagnostic Procedures on Diagnosis, Therapy, and Outcome in Horses with Headshaking: Recommendations for Fast-Track Advanced Diagnostic and Therapeutic Protocols Open
Most horses affected by headshaking (HS) are diagnosed with idiopathic trigeminal-mediated headshaking (i-TMHS) when no underlying disease is found. Diagnosis is made by the exclusion of differentials considering history, clinical signs, a…
<i>Schiff‐Sherrington syndrome</i> in a 7‐year‐old zebra mare ( <i>Equus quagga</i> ) Open
Summary A 7‐year‐old plains zebra (Equus quagga) mare was presented to the Clinic for Horses, University of Veterinary Medicine Hannover, Foundation, Germany as an emergency. The owner reported that the mare was unable to stand after a sus…
Dentigerous cysts with exostosis of the temporal bone in horses – A new variant diagnosed by computed tomography Open
Summary The dentigerous cyst or temporal teratoma in horses is a well‐known congenital malformation that occurs in the temporal region and usually contains dental tissue. This case report describes two horses with a previously unreported v…
CT myelographic diagnosis of ligamentum flavum hypertrophy in a Warmblood Gelding with progressive ataxia Open
An 8‐year‐old Warmblood gelding presented with a history of progressive ataxia for 6 weeks. Intra‐ and intervertebral ratios measured from lateral radiographs of the cervical spine were within normal limits. Computed tomographic myelograph…
A Rare Case of Vascular Proliferation in the Mandible of a Juvenile Horse Open
A fast growing, circumscribed, unilateral swelling of the right mandible of a juvenile horse was observed. Within few weeks, the continuously growing mass reached dimensions ranging from 7 to 10 cm in diameter and resulted in loss of the f…
High‐field (3 Tesla) MRI of the navicular apparatus of sound horses shows good agreement to histopathology Open
Magnetic resonance imaging and the correlation to histopathological findings of the equine palmar foot of lame horses have been described previously, using 0.27 and 1.5 T systems. Compared to these, 3 T systems provide superior spatial res…
Genome‐wide association analysis for lethal brachycephalic‐like facial dysmorphia in Labrador Retrievers Open
Summary A GWAS was performed for inborn X‐linked facial dysmorphia with severe growth retardation in Labrador Retrievers. This lethal condition was mapped on the X chromosome at 17–21 Mb and supported by eight SNPs in complete LD. Dams of …
<i>De-novo</i> variants in <i>XIRP1</i> associated with polydactyly and polysyndactyly in Holstein cattle Open
Congenital polydactylous cattle are sporadically observed. Impairment of the limb patterning process due to altered control of the zone of polarizing activity (ZPA) was associated in several species with preaxial polydactyly and syndactyly…
Additional file 5: of Germline mutation within COL2A1 associated with lethal chondrodysplasia in a polled Holstein family Open
Primer pairs used for sequencing exon 42 of COL2A1 on BTA5. Primer pairs, amplicon size (AS) in base pairs (bp) and the annealing temperature (AT) are given. (DOCX 14Â kb)
Additional file 1: of Germline mutation within COL2A1 associated with lethal chondrodysplasia in a polled Holstein family Open
Results of the filtering analysis for variants heterozygous or homozygous mutant in a bulldog calf and a sperm sample of the sire Energy P but missing in an unaffected progeny of Energy P. Shown are the filtered genes containing variants w…
Additional file 3: of Germline mutation within COL2A1 associated with lethal chondrodysplasia in a polled Holstein family Open
Genotyping of all three bulldog calves, a sperm sample of their sire Energy P, the dams of the bulldog calves and an unrelated control animal using a PCR restriction fragment polymorphism (PCR-RFLP). Samples with fragment sizes of 394 bp, …