Charlotte Wright
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View article: The LMSz method - an automatable scalable approach to constructing gene-specific growth charts in rare disorders
The LMSz method - an automatable scalable approach to constructing gene-specific growth charts in rare disorders Open
Children with monogenic neurodevelopmental disorders often grow abnormally. Gene-specific growth charts would be useful but require large samples to construct them using the conventional LMS method. We transformed anthropometry to British …
View article: The cost-effectiveness of education and support group interventions aimed at promoting breastfeeding
The cost-effectiveness of education and support group interventions aimed at promoting breastfeeding Open
Breastfeeding, especially exclusive, is associated with long-lasting health benefits to mothers and babies and healthcare cost-savings; however, breastfeeding rates are low in many high-income countries. Education and support interventions…
View article: Management of Expected Intraocular Pressure (IOP) Elevation During Prolonged Steep Trendelenburg Positioning: A Case Report and Literature Review
Management of Expected Intraocular Pressure (IOP) Elevation During Prolonged Steep Trendelenburg Positioning: A Case Report and Literature Review Open
This article presents a case of intraocular pressure (IOP) assessment and perioperative management in a patient with primary open-angle glaucoma undergoing a prolonged surgical procedure in steep Trendelenburg (ST) positioning. The patient…
View article: GlaucoRAG: A Retrieval-Augmented Large Language Model for Expert-Level Glaucoma Assessment
GlaucoRAG: A Retrieval-Augmented Large Language Model for Expert-Level Glaucoma Assessment Open
Purpose Purpose: Accurate glaucoma assessment is challenging because of the complexity and chronic nature of the disease; therefore, there is a critical need for models that provide evidence-based, accurate assessment. The purpose of this …
View article: Performance of DeepSeek, Qwen 2.5 MAX, and ChatGPT Assisting in Diagnosis of Corneal Eye Diseases, Glaucoma, and Neuro-Ophthalmology Diseases Based on Clinical Case Reports
Performance of DeepSeek, Qwen 2.5 MAX, and ChatGPT Assisting in Diagnosis of Corneal Eye Diseases, Glaucoma, and Neuro-Ophthalmology Diseases Based on Clinical Case Reports Open
Background This study evaluates the diagnostic performance of several AI models, including Deepseek, in diagnosing corneal diseases, glaucoma, and neuro□ophthalmologic disorders. Methods We retrospectively selected 53 case reports from the…
View article: Referee report. For: Exploring Breastfeeding Mothers’ and Lactation Consultants’ Experiences of Lactation Consultancy Throughout the Restrictions Put in Place Due to the COVID-19 Pandemic [version 2; peer review: 3 approved, 1 approved with reservations]
Referee report. For: Exploring Breastfeeding Mothers’ and Lactation Consultants’ Experiences of Lactation Consultancy Throughout the Restrictions Put in Place Due to the COVID-19 Pandemic [version 2; peer review: 3 approved, 1 approved with reservations] Open
View article: An assessment of energy compensation in malnourished and healthy children in urban Ghana: a standardized satiation study
An assessment of energy compensation in malnourished and healthy children in urban Ghana: a standardized satiation study Open
View article: Short-term weight variability in infants and toddlers: an observational study
Short-term weight variability in infants and toddlers: an observational study Open
Aims To explore short-term weight variability in young children; (1) how it relates to expected weight gain and (2) how it is affected by age, time of day and dietary intakes and outputs. Methods Twenty healthy infants aged 2–10 months and…
View article: Maternal and pregnancy factors contributing to the association between area deprivation and infant mortality in England: a retrospective cohort study
Maternal and pregnancy factors contributing to the association between area deprivation and infant mortality in England: a retrospective cohort study Open
UK Medical Research Council, Scottish Chief Scientist Office, Wellcome Trust.
View article: The LMSz method - an automatable scalable approach to constructing gene-specific growth charts in rare disorders
The LMSz method - an automatable scalable approach to constructing gene-specific growth charts in rare disorders Open
Introduction Children with monogenic neurodevelopmental disorders often grow abnormally. Gene-specific growth charts would be useful but require large samples to construct them using the conventional LMS method. Methods We transformed anth…
View article: Weight Velocity in Addition to Latest Weight Does Not Improve the Identification of Wasting or the Prediction of Stunting and Mortality: A Longitudinal Analysis Using Data from Malawi, South Africa, and Pakistan
Weight Velocity in Addition to Latest Weight Does Not Improve the Identification of Wasting or the Prediction of Stunting and Mortality: A Longitudinal Analysis Using Data from Malawi, South Africa, and Pakistan Open
The key anthropometric determinant of impending wasting, stunting, and mortality appears to be how far below the normal range the child's weight is, rather than how they reached that position.
View article: Associations between breastfeeding duration and adherence to complementary feeding recommendations in Scotland
Associations between breastfeeding duration and adherence to complementary feeding recommendations in Scotland Open
We aimed to describe how breastfeeding relates to adherence to complementary feeding (CF) recommendations, diet diversification and feeding skills development and whether sociodemographic factors explain any differences observed. The Scott…
View article: Does planning to mixed feed undermine breastfeeding?
Does planning to mixed feed undermine breastfeeding? Open
Continued breastfeeding is important for infants' health, but it is unclear whether mixed feeding increases the risk of breastfeeding cessation. We aimed to explore associations of mixed feeding and lactation problems with early cessation …
View article: Evaluation of the Healthy Start voucher scheme on maternal vitamin use and child breastfeeding: a natural experiment using data linkage
Evaluation of the Healthy Start voucher scheme on maternal vitamin use and child breastfeeding: a natural experiment using data linkage Open
Background Having a good start in life during pregnancy and infancy has been shown to be important for living both a healthy life and a longer life. Despite the introduction of many policies for the early-years age group, including voucher…
View article: Digital preconception interventions targeting weight, diet and physical activity: A systematic review
Digital preconception interventions targeting weight, diet and physical activity: A systematic review Open
Aim Optimising preconception health increases the likelihood of conception, positively influences short‐ and long‐term pregnancy outcomes and reduces intergenerational chronic disease risk. Our aim was to synthesise study characteristics a…
View article: Relative cost of counselling compared to supplementary foods for acute malnutrition: a time and motion study in Nairobi Kenya
Relative cost of counselling compared to supplementary foods for acute malnutrition: a time and motion study in Nairobi Kenya Open
Aims We aimed to describe the relative cost of supplying supplementary food, compared to counselling, in children with acute malnutrition managed in one urban area. Method A cross-sectional costing study was undertaken. Interviews with sta…
View article: Infancy weight faltering and childhood neuro-developmental disorders: A general population birth-cohort study:a general population birth-cohort study
Infancy weight faltering and childhood neuro-developmental disorders: A general population birth-cohort study:a general population birth-cohort study Open
While it is known that intrauterine growth restriction is associated with later mental disorders, it is still unclear whether similar associations exists for postnatal weight faltering, also known as ‘failure to thrive’ in infancy. This st…
View article: Growth patterns in children and adolescents with cerebral palsy from Argentina and Germany
Growth patterns in children and adolescents with cerebral palsy from Argentina and Germany Open
To analyze growth patterns of children with CP between countries; to examine differences in growth; and to assess the fit of growth charts. Cross-sectional study in children with CP from 2 to 19 years old, 399 from Argentina and 400 from G…
View article: Healthcare professionals, breast milk substitutes and corporate sponsorship
Healthcare professionals, breast milk substitutes and corporate sponsorship Open
International audience
View article: How much do preverbal children signal a wish to be fed? Nested case control study comparing weight faltering and healthy infants
How much do preverbal children signal a wish to be fed? Nested case control study comparing weight faltering and healthy infants Open
Infants were commonly disengaged during meals, but a majority accepted food despite this. Those with weight faltering did not differ compared to healthy controls.
View article: Weight loss during ambulatory tube weaning: don’t put the feeds back up
Weight loss during ambulatory tube weaning: don’t put the feeds back up Open
Objective To describe the prevalence of weight loss during tube weaning and its impact on wean duration and growth. Setting Tertiary feeding clinic, UK. Patients All children seen for weaning from long-term enteral feeding between 2008 and…
View article: Do children and adolescents with cerebral palsy from Argentina and Germany grow differently?
Do children and adolescents with cerebral palsy from Argentina and Germany grow differently? Open
Purpose: To analyze growth patterns of children with CP between countries; to examine differences in growth; and to assess the fit of growth charts. Methods: Cross-sectional study in children with CP from 2 to 19 years old, 399 from Argent…
View article: Body composition data show that high BMI centiles overdiagnose obesity in children aged under 6 years
Body composition data show that high BMI centiles overdiagnose obesity in children aged under 6 years Open
View article: Association of Early Nutritional Status With Child Development in the Asia Pacific Region
Association of Early Nutritional Status With Child Development in the Asia Pacific Region Open
HFA, BMI-for-age, and body fat proportion were independently associated with ECD, and these findings suggest that future studies should consider using these parameters to estimate the prevalence of child underdevelopment; nutritional trial…
View article: Impact of high energy oral nutritional supplements consumed in the late afternoon on appetite, energy intake and cardio-metabolic risk factors in females with lower BMI
Impact of high energy oral nutritional supplements consumed in the late afternoon on appetite, energy intake and cardio-metabolic risk factors in females with lower BMI Open
View article: Enriched formula milks and academic performance in later childhood
Enriched formula milks and academic performance in later childhood Open
View article: Assessing the optimal time interval between growth measurements using a combined data set of weights and heights from 5948 infants
Assessing the optimal time interval between growth measurements using a combined data set of weights and heights from 5948 infants Open
Background Current guidance on the optimum interval between measurements in infancy is not evidence based. We used routine data to explore how measurement error and short-term variation (‘noise’) might affect interpretation of infant weigh…
View article: Childhood stunting and micronutrient status unaffected by RCT of micronutrient fortified drink
Childhood stunting and micronutrient status unaffected by RCT of micronutrient fortified drink Open
Micronutrient supplementation is widely used to prevent stunting in children under 5 years in low‐ and middle‐income countries (LMIC), but the impact of treatment has been disappointing, possibly due to non‐compliance. Our aim was to deliv…
View article: Prevalence and overlap of known undernutrition risk factors in children in Nairobi Kenya
Prevalence and overlap of known undernutrition risk factors in children in Nairobi Kenya Open
We aimed to describe the co‐occurrence of known risk factors for undernutrition and the prevalence of modifiable risks in wasted, stunted and healthy children. Quota sampling was used to recruit healthy [weight for age Z scores (WAZ) > −2 …
View article: Development of a Scale to Measure Infant Eating Behaviour Worldwide
Development of a Scale to Measure Infant Eating Behaviour Worldwide Open
In order to create a short, internationally valid scale to assess eating behaviour (EB) in young children at risk of undernutrition, we refined 15 phrases describing avidity or food refusal (avoidance). In study one, 149 parents matched ph…