Margarita Smirnov
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View article: A single-cell compendium of human cerebrospinal fluid identifies disease-associated immune cell populations
A single-cell compendium of human cerebrospinal fluid identifies disease-associated immune cell populations Open
Single-cell transcriptomics applied to cerebrospinal fluid (CSF) for elucidating the pathophysiology of neurologic diseases has produced only a preliminary characterization of CSF immune cells. CSF derives from and borders central nervous …
View article: Fish Welfare – A Case Study: Reviling for the first-time side effects of vaccination in European sea bass ( <i>Dicentrarchus labrax</i> ) and barramundi ( <i>Lates calcarifer</i> ) in the Israeli fish farming
Fish Welfare – A Case Study: Reviling for the first-time side effects of vaccination in European sea bass ( <i>Dicentrarchus labrax</i> ) and barramundi ( <i>Lates calcarifer</i> ) in the Israeli fish farming Open
Vaccination is an effective way to control many infectious diseases in fish. Israeli fish farming has successfully used two vaccines over the last 30 years and has no problem with the side effects of vaccination. However, after introducing…
View article: The Tilapia Cyst Tissue Enclosing the Proliferating Myxobolus bejeranoi Parasite Exhibits Cornified Structure and Immune Barrier Function
The Tilapia Cyst Tissue Enclosing the Proliferating Myxobolus bejeranoi Parasite Exhibits Cornified Structure and Immune Barrier Function Open
Myxozoa, a unique group of obligate endoparasites within the phylum Cnidaria, can cause emerging diseases in wild and cultured fish populations. Recently, the myxozoan Myxobolus bejeranoi has been identified as a prevalent pathogen infecti…
View article: The Molecular Mechanisms Employed by the Parasite Myxobolus bejeranoi (Cnidaria: Myxozoa) from Invasion through Sporulation for Successful Proliferation in Its Fish Host
The Molecular Mechanisms Employed by the Parasite Myxobolus bejeranoi (Cnidaria: Myxozoa) from Invasion through Sporulation for Successful Proliferation in Its Fish Host Open
Myxozoa is a unique group of obligate endoparasites in the phylum Cnidaria that can cause emerging diseases in wild and cultured fish populations. Recently, we identified a new myxozoan species, Myxobolus bejeranoi, which infects the gills…
View article: The myxozoan parasite <i>Myxobolus bejeranoi</i> (Cnidaria: Myxozoa) infection dynamics and host specificity in hybrid tilapia aquaculture
The myxozoan parasite <i>Myxobolus bejeranoi</i> (Cnidaria: Myxozoa) infection dynamics and host specificity in hybrid tilapia aquaculture Open
Nile × blue tilapia hybrid ( Oreochromis niloticus × O. aureus ) has become an important food fish in intensive freshwater aquaculture. Recently, the parasite Myxobolus bejeranoi (Cnidaria: Myxozoa) was found to infect hybrid tilapia gills…
View article: Infection by the Parasite Myxobolus bejeranoi (Cnidaria: Myxozoa) Suppresses the Immune System of Hybrid Tilapia
Infection by the Parasite Myxobolus bejeranoi (Cnidaria: Myxozoa) Suppresses the Immune System of Hybrid Tilapia Open
Myxozoa (Cnidaria) is a large group of microscopic obligate endoparasites that can cause emerging diseases, affecting wild fish populations and fisheries. Recently, the myxozoan Myxobolus bejeranoi was found to infect the gills of hybrid t…
View article: Infection by the parasite Myxobolus bejeranoi (Cnidaria: Myxozoa) suppresses the immune system of hybrid tilapia
Infection by the parasite Myxobolus bejeranoi (Cnidaria: Myxozoa) suppresses the immune system of hybrid tilapia Open
Background: Tilapia is the second most cultured fish worldwide and in Israel, it constitutes 60% of total production. Recently, the myxozoan parasite Myxobolus bejeranoi was found to infect the gills of hybrid tilapia (Nile tilapia ( Oreoc…
View article: Common and newly discovered pathogens in the Israeli Mediterranean Sea mariculture
Common and newly discovered pathogens in the Israeli Mediterranean Sea mariculture Open
In the last few decades, the farming of different fish species in Israeli mariculture gradually increased. This paper aims to present the last 15 years’ study results that define the most significant fish pathogens and evaluate their seaso…
View article: Sex-specific regulation of metabolic health and vertebrate lifespan by AMP biosynthesis
Sex-specific regulation of metabolic health and vertebrate lifespan by AMP biosynthesis Open
Energy homeostasis is disrupted with age, which then fuels multiple age-related pathologies. The AMP-activated protein kinase (AMPK) is the primary sensor of cellular energy in eukaryotes. However, the genetic regulation of vertebrate agin…
View article: First report of Iridovirus (ISKNV) infection in Israeli mariculture gilthead sea bream (Sparus aurata) at the Mediterranean Sea
First report of Iridovirus (ISKNV) infection in Israeli mariculture gilthead sea bream (Sparus aurata) at the Mediterranean Sea Open
Megalocytiviruses have caused mass mortalities in various farmed fish species, both edible and ornamental. Infectious spleen and kidney necrosis virus (ISKNV) belongs to this family of viruses and induces lethal diseases in cultured fish. …
View article: Fish Welfare: the use of CO2 to avoid fish suffering during preparation to processing
Fish Welfare: the use of CO2 to avoid fish suffering during preparation to processing Open
Fish welfare has become a significant concern during the last decade. The issue of slaughter is getting the interest of many consumer organizations and fish growers, and suppliers. We need to take careful consideration to food fish slaught…
View article: Forty years of fluctuation in the occurrence of two various metazoan parasites: Contracaecum multipapillatum (Nematoda) and Digenean metacercaria N1 in warm water fish culture in the Israeli farms
Forty years of fluctuation in the occurrence of two various metazoan parasites: Contracaecum multipapillatum (Nematoda) and Digenean metacercaria N1 in warm water fish culture in the Israeli farms Open
We present field observation results from October 2019 to February 2021 in Israeli fish farms. Surprisingly, two metazoan parasites, the larvae of Contracaecum multipapillatum and unidentified metacercaria N1, which disappeared from Israel…
View article: Parasitological Survey of Cichlidae in the Sea-of-Galilee
Parasitological Survey of Cichlidae in the Sea-of-Galilee Open
The results of a parasitological survey conducted since January 2012 till January 2014 in the littoral zone of the Sea-of-Galilee are presented. The parasites were identified, and their prevalence, density, and geographic distribution were…
View article: Evidence of Increased Antibiotic Resistance in Phylogenetically-Diverse Aeromonas Isolates from Semi-Intensive Fish Ponds Treated with Antibiotics
Evidence of Increased Antibiotic Resistance in Phylogenetically-Diverse Aeromonas Isolates from Semi-Intensive Fish Ponds Treated with Antibiotics Open
The genus Aeromonas is ubiquitous in aquatic environments encompassing a broad range of fish and human pathogens. Aeromonas strains are known for their enhanced capacity to acquire and exchange antibiotic resistance genes and therefore, ar…