Margaux J. Heuschkel
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View article: Caractérisation de la Janus kinase JAK1 comme facteur d’hôte du virus de l’hépatite D et cible antivirale
Caractérisation de la Janus kinase JAK1 comme facteur d’hôte du virus de l’hépatite D et cible antivirale Open
Chronic hepatitis D is the most severe form of chronic viral hepatitis and results from co-infection of the liver by hepatitis B virus (HBV) and its satellite virus, hepatitis D virus (HDV). The recent clinical approval of bulevirtide, an …
View article: Cell-based cccDNA reporter assay combined with functional genomics identifies YBX1 as HBV cccDNA host factor and antiviral candidate target
Cell-based cccDNA reporter assay combined with functional genomics identifies YBX1 as HBV cccDNA host factor and antiviral candidate target Open
Objectives Chronic hepatitis B virus (HBV) infection is a leading cause of liver disease and hepatocellular carcinoma. A key feature of HBV replication is the synthesis of the covalently close circular (ccc)DNA, not targeted by current tre…
View article: A stable hepatitis D virus-producing cell line for host target and drug discovery
A stable hepatitis D virus-producing cell line for host target and drug discovery Open
Chronic hepatitis D is the most aggressive form of chronic viral hepatitis. It is caused by super-infection of hepatitis B virus (HBV)-infected hepatocytes with hepatitis D virus (HDV). While the recent conditional approval of bulevirtide …
View article: Cell Culture Models for the Study of Hepatitis D Virus Entry and Infection
Cell Culture Models for the Study of Hepatitis D Virus Entry and Infection Open
Chronic hepatitis D is one of the most severe and aggressive forms of chronic viral hepatitis with a high risk of developing hepatocellular carcinoma (HCC). It results from the co-infection of the liver with the hepatitis B virus (HBV) and…