Margot Rohrer
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View article: An Expanded Access Protocol of <scp>RNS60</scp> in Amyotrophic Lateral Sclerosis
An Expanded Access Protocol of <span>RNS60</span> in Amyotrophic Lateral Sclerosis Open
Aims RNS60 is an investigational product in clinical development for amyotrophic lateral sclerosis (ALS). RNS60 slowed disease progression in the ALS SOD1 G93A mouse model and was safe and well tolerated both in an open‐label pilot study a…
View article: Expanded access protocol (<scp>EAP</scp>) program for access to investigational products for amyotrophic lateral sclerosis (<scp>ALS</scp>)
Expanded access protocol (<span>EAP</span>) program for access to investigational products for amyotrophic lateral sclerosis (<span>ALS</span>) Open
Introduction/Aims Expanded access protocols (EAPs) are a Food and Drug Administration (FDA)‐regulated pathway for granting access to investigational products (IPs) to individuals with serious diseases who are ineligible for clinical trials…
View article: Safety and activity of <scp>anti‐CD14</scp> antibody <scp>IC14</scp> (atibuclimab) in <scp>ALS</scp>: Experience with expanded access protocol
Safety and activity of <span>anti‐CD14</span> antibody <span>IC14</span> (atibuclimab) in <span>ALS</span>: Experience with expanded access protocol Open
Introduction/Aims IC14 (atibuclimab) is a monoclonal anti‐CD14 antibody. A previous phase 1 trial of 10 participants with amyotrophic lateral sclerosis (ALS) demonstrated initial safety of IC14 in an acute treatment setting. We provided lo…
View article: An expanded access protocol of <scp>RT001</scp> in amyotrophic lateral sclerosis—Initial experience with a lipid peroxidation inhibitor
An expanded access protocol of <span>RT001</span> in amyotrophic lateral sclerosis—Initial experience with a lipid peroxidation inhibitor Open
Introduction/Aims Lipid peroxidation is thought to play a biologically important role in motor neuron death in amyotrophic lateral sclerosis (ALS). 11,11 Di‐deuterated linoleic ethyl ester (RT001) prevents lipid peroxidation in cellular an…