María A. Poca
YOU?
Author Swipe
View article: Osmotic Fragility in Leukodepleted Stored Red Blood Cells: Implications for Neurocritical Care Transfusion Strategies
Osmotic Fragility in Leukodepleted Stored Red Blood Cells: Implications for Neurocritical Care Transfusion Strategies Open
Background: Anemia is frequent in critically ill patients with traumatic brain injury (TBI) and worsens neurological outcomes. Red blood cell (RBC) transfusion is a cornerstone of management, but storage-related biochemical and structural …
View article: KidsBrainIT: Visualization of the Impact of Cerebral Perfusion Pressure Insult Intensity and Duration on Childhood Brain Trauma Outcome
KidsBrainIT: Visualization of the Impact of Cerebral Perfusion Pressure Insult Intensity and Duration on Childhood Brain Trauma Outcome Open
Background Cerebral perfusion pressure (CPP) dose–response on post–traumatic brain injury (TBI) outcome in children remains unknown. This project aimed to produce the first pediatric post-TBI CPP dose–response visualization plot from the i…
View article: Continuous Intracranial Pressure Monitoring in Children with ‘Benign’ External Hydrocephalus
Continuous Intracranial Pressure Monitoring in Children with ‘Benign’ External Hydrocephalus Open
Background/Objectives: This study aimed to evaluate the results of continuous intracranial pressure (ICP) monitoring in children with macrocephaly or rapidly increasing head circumference (HC) diagnosed as benign external hydrocephalus (BE…
View article: Hybrid diffuse optical appraisal of peripheral and cerebral changes in critically ill patients receiving red blood cell transfusion
Hybrid diffuse optical appraisal of peripheral and cerebral changes in critically ill patients receiving red blood cell transfusion Open
View article: How the heterogeneity of the severely injured brain affects hybrid diffuse optical signals: case examples and guidelines
How the heterogeneity of the severely injured brain affects hybrid diffuse optical signals: case examples and guidelines Open
Significance: A shortcoming for the routine clinical use of diffuse optics (DO) in the injured head has been that the results from commercial near-infrared spectroscopy-based devices are not reproducible, often give phys iologically invali…
View article: Surgical Outcomes in Chiari 1 and Chiari 1.5 Malformation Treated by Posterior Fossa Reconstruction: A Comprehensive Analysis of 110 Pediatric Cases and Literature Review
Surgical Outcomes in Chiari 1 and Chiari 1.5 Malformation Treated by Posterior Fossa Reconstruction: A Comprehensive Analysis of 110 Pediatric Cases and Literature Review Open
Background/Objectives: The management of Chiari malformations (CMs) remains a clinical challenge and a topic of great controversy. Results may vary between children and adults. The purpose of the current single-center study is to criticall…
View article: Performance of glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) biomarkers in predicting CT scan results and neurological outcomes in children with traumatic brain injury (BRAINI-2 paediatric study): protocol of a European prospective multicentre study
Performance of glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) biomarkers in predicting CT scan results and neurological outcomes in children with traumatic brain injury (BRAINI-2 paediatric study): protocol of a European prospective multicentre study Open
Introduction In light of the burden of traumatic brain injury (TBI) in children and the excessive number of unnecessary CT scans still being performed, new strategies are needed to limit their use while minimising the risk of delayed diagn…
View article: Hybrid diffuse optical appraisal of peripheral and cerebral changes in critically ill patients receiving red blood cell transfusion
Hybrid diffuse optical appraisal of peripheral and cerebral changes in critically ill patients receiving red blood cell transfusion Open
Background Red blood cells transfusions (RBCT) are utilized to restore normal values of hemoglobin concentration and hematocrit percentage in anemic patients. As expected, RBCT often leads to local and global alteration of blood flow (BF) …
View article: Consensus-based recommendations for diagnosis and surgical management of cranioplasty and post-traumatic hydrocephalus from a European panel
Consensus-based recommendations for diagnosis and surgical management of cranioplasty and post-traumatic hydrocephalus from a European panel Open
View article: Erratum: Transcranial optical monitoring for detecting intracranial pressure alterations in children with benign external hydrocephalus: a proof-of-concept study
Erratum: Transcranial optical monitoring for detecting intracranial pressure alterations in children with benign external hydrocephalus: a proof-of-concept study Open
[This corrects the article DOI: 10.1117/1.NPh.9.4.045005.].
View article: The Role of Neurophysiology in Managing Patients with Chiari Malformations
The Role of Neurophysiology in Managing Patients with Chiari Malformations Open
Chiari malformation type 1 (CM1) includes various congenital anomalies that share ectopia of the cerebellar tonsils lower than the foramen magnum, in some cases associated with syringomyelia or hydrocephalus. CM1 can cause dysfunction of t…
View article: Intraoperative Neurophysiological Monitoring in Syringomyelia Surgery: A Multimodal Approach
Intraoperative Neurophysiological Monitoring in Syringomyelia Surgery: A Multimodal Approach Open
Syringomyelia can be associated with multiple etiologies. The treatment of the underlying causes is first-line therapy; however, a direct approach to the syrinx is accepted as rescue treatment. Any direct intervention on the syrinx require…
View article: The Role of Neurophysiology in Managing Patients with Chiari Malformations
The Role of Neurophysiology in Managing Patients with Chiari Malformations Open
Chiari malformation type 1 (CM1) includes a series of congenital anomalies that share ectopia of the cerebellar tonsils below the foramen magnum, in some cases associated with syringomyelia or hydrocephalus. CM1 can cause dysfunction of th…
View article: A Critical Update of the Classification of Chiari and Chiari-like Malformations
A Critical Update of the Classification of Chiari and Chiari-like Malformations Open
Chiari malformations are a group of craniovertebral junction anomalies characterized by the herniation of cerebellar tonsils below the foramen magnum, often accompanied by brainstem descent. The existing classification systems for Chiari m…
View article: Intraoperative Neurophysiological Monitoring in Syringomyelia Surgery: A Multimodal Approach
Intraoperative Neurophysiological Monitoring in Syringomyelia Surgery: A Multimodal Approach Open
Syringomyelia can be associated with multiple etiologies. The treatment of the underlying causes is the first-line therapy, however, a direct approach to the syrinx is accepted as rescue treatment. Any direct intervention on the syrinx req…
View article: Study protocol for investigating the clinical performance of an automated blood test for glial fibrillary acidic protein and ubiquitin carboxy-terminal hydrolase L1 blood concentrations in elderly patients with mild traumatic BRAIN Injury and reference values (BRAINI-2 Elderly European study): a prospective multicentre observational study
Study protocol for investigating the clinical performance of an automated blood test for glial fibrillary acidic protein and ubiquitin carboxy-terminal hydrolase L1 blood concentrations in elderly patients with mild traumatic BRAIN Injury and reference values (BRAINI-2 Elderly European study): a prospective multicentre observational study Open
Introduction Two blood brain-derived biomarkers, glial fibrillar acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), can rule out intracranial lesions in patients with mild traumatic brain injury (mTBI) when assesse…
View article: Transcranial, Non-Invasive Evaluation of Potential Misery Perfusion During Hyperventilation Therapy of Traumatic Brain Injury Patients
Transcranial, Non-Invasive Evaluation of Potential Misery Perfusion During Hyperventilation Therapy of Traumatic Brain Injury Patients Open
Hyperventilation (HV) therapy uses vasoconstriction to reduce intracranial pressure (ICP) by reducing cerebral blood volume. However, as HV also lowers cerebral blood flow (CBF), it may provoke misery perfusion (MP), in which the decrease …
View article: Comparison of cerebral metabolic rate of oxygen, blood flow, and bispectral index under general anesthesia
Comparison of cerebral metabolic rate of oxygen, blood flow, and bispectral index under general anesthesia Open
Optics can reliably monitor in such conditions.
View article: Preterm Birth and Early Life Environmental Factors: Neuropsychological Profiles at Adolescence and Young Adulthood
Preterm Birth and Early Life Environmental Factors: Neuropsychological Profiles at Adolescence and Young Adulthood Open
Background There is a lack of knowledge about whether preterm birth might lead to a greater susceptibility to early life environmental factors. The aim of this study was to establish the neuropsychological profiles in high- and low-risk pr…
View article: Transcranial optical monitoring for detecting intracranial pressure alterations in children with benign external hydrocephalus: a proof-of-concept study
Transcranial optical monitoring for detecting intracranial pressure alterations in children with benign external hydrocephalus: a proof-of-concept study Open
We revealed the presence of and BFI variations-detectable with optical techniques-during ICP B-waves in BEH children. Finally, the feasibility of detecting ICP B-waves in hemodynamic time traces obtained noninvasively was shown.
View article: ERN CRANIO patient coverage of craniosynostosis in Europe
ERN CRANIO patient coverage of craniosynostosis in Europe Open
View article: Impact of the COVID-19 pandemic on the incidence and type of infections in hospitalized patients with cirrhosis
Impact of the COVID-19 pandemic on the incidence and type of infections in hospitalized patients with cirrhosis Open
View article: Correction to: Diagnosis and treatment of Chiari Malformation and syringomyelia in adults: International Consensus Document
Correction to: Diagnosis and treatment of Chiari Malformation and syringomyelia in adults: International Consensus Document Open
View article: Diagnosis and treatment of Chiari malformation type 1 in children: the International Consensus Document
Diagnosis and treatment of Chiari malformation type 1 in children: the International Consensus Document Open
View article: Rare functional genetic variants in COL7A1, COL6A5, COL1A2 and COL5A2 frequently occur in Chiari Malformation Type 1
Rare functional genetic variants in COL7A1, COL6A5, COL1A2 and COL5A2 frequently occur in Chiari Malformation Type 1 Open
Chiari Malformation Type 1 (CM-1) is characterized by herniation of the cerebellar tonsils below the foramen magnum and the presence of headaches and other neurologic symptoms. Cranial bone constriction is suspected to be the most common b…
View article: Neurodevelopmental profile in children with benign external hydrocephalus syndrome. A pilot cohort study
Neurodevelopmental profile in children with benign external hydrocephalus syndrome. A pilot cohort study Open
View article: How to Choose a Shunt for Patients with Normal Pressure Hydrocephalus: A Short Guide to Selecting the Best Shunt Assembly
How to Choose a Shunt for Patients with Normal Pressure Hydrocephalus: A Short Guide to Selecting the Best Shunt Assembly Open
Most patients with hydrocephalus are still managed with the implantation of a cerebrospinal fluid (CSF) shunt in which the CSF flow is regulated by a differential-pressure valve (DPV). Our aim in this review is to discuss some basic concep…
View article: Reduced hippocampal subfield volumes and memory performance in preterm children with and without germinal matrix-intraventricular hemorrhage
Reduced hippocampal subfield volumes and memory performance in preterm children with and without germinal matrix-intraventricular hemorrhage Open
View article: Considerations in the Use of Gravitational Valves in the Management of Hydrocephalus. Some Lessons Learned with the Dual-Switch Valve
Considerations in the Use of Gravitational Valves in the Management of Hydrocephalus. Some Lessons Learned with the Dual-Switch Valve Open
In the past decade, there has been a clear trend towards better outcomes in patients with hydrocephalus, especially those with normal pressure hydrocephalus (NPH). This is partly due to the availability of more sophisticated hardware and a…
View article: To Shunt or Not to Shunt Patients with Idiopathic Normal Pressure Hydrocephalus? A Reappraisal of an Old Question
To Shunt or Not to Shunt Patients with Idiopathic Normal Pressure Hydrocephalus? A Reappraisal of an Old Question Open
The possibility that the cerebral ventricles can dilate without any increase in the pressure of the cerebrospinal fluid (CSF) was recognized in 1935 by Penfield who reported a patient in whom “…the cerebrospinal fluid spaces are closed and…