Misael Uribe
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View article: Artificial Light at Night, Sleep Disruption, and Liver Health: Implications for MASLD Pathogenesis
Artificial Light at Night, Sleep Disruption, and Liver Health: Implications for MASLD Pathogenesis Open
This narrative review explores the role of artificial light at night (ALAN) as an emerging environmental determinant of liver and metabolic health, with particular emphasis on its contribution to metabolic dysfunction-associated steatotic …
View article: Clinical and molecular implications of antipsychotics in MASLD
Clinical and molecular implications of antipsychotics in MASLD Open
Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), has emerged as a major comorbidity among patients with severe mental illness (SMI), particularly those treated w…
View article: Immunonutrition: Another Player on the MASLD Field
Immunonutrition: Another Player on the MASLD Field Open
Immunonutrition is a nutritional strategy where the bioactive properties of nutrients from the diet are used to modulate metabolic pathways, inflammation signals, and oxidative stress regulators. Metabolic dysfunction-associated steatotic …
View article: The pathophysiological link between type 1 diabetes and MASLD: insights into insulin resistance and liver dysfunction
The pathophysiological link between type 1 diabetes and MASLD: insights into insulin resistance and liver dysfunction Open
Type 1 Diabetes Mellitus (T1DM) is an autoimmune disorder characterized by the destruction of pancreatic β-cells, leading to significant endogenous insulin deficiency. In this context, inflammation plays a crucial role in the pathogenesis …
View article: Metabolic-Dysfunction-Associated Steatotic Liver Disease: Molecular Mechanisms, Clinical Implications, and Emerging Therapeutic Strategies
Metabolic-Dysfunction-Associated Steatotic Liver Disease: Molecular Mechanisms, Clinical Implications, and Emerging Therapeutic Strategies Open
Metabolic-dysfunction-associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), is a highly prevalent metabolic disorder characterized by hepatic steatosis in conjunction with at least one c…
View article: Fournier's Gangrene in Neonates: A Case Report and Literature Review
Fournier's Gangrene in Neonates: A Case Report and Literature Review Open
Fournier's gangrene is a severe, rapidly progressing necrotizing fasciitis with a high capacity for compromising tissues at different levels. It primarily affects perianal and genital areas with a high mortality rate due to extensive impac…
View article: Analisis de la Movilidad Urbana Sostenible en Medellin-Colombia Corredor Vial Tranvia de Ayacucho
Analisis de la Movilidad Urbana Sostenible en Medellin-Colombia Corredor Vial Tranvia de Ayacucho Open
La movilidad urbana es un aspecto crucial en la configuración de la sostenibilidad y funcionalidad de las ciudades. En este artículo se realiza un análisis de la movilidad urbana en el Corredor Vial Calle 49 de Medellín, Colombia con datos…
View article: Periprocedural and perioperative anticoagulation management strategies in liver cirrhosis
Periprocedural and perioperative anticoagulation management strategies in liver cirrhosis Open
View article: Factor XI/XIa inhibitors for splanchnic vein thrombosis associated with liver cirrhosis: Is there any potential role?
Factor XI/XIa inhibitors for splanchnic vein thrombosis associated with liver cirrhosis: Is there any potential role? Open
View article: Estrategias de manejo perioperatorio y periprocedimiento de la anticoagulación en la cirrosis hepática
Estrategias de manejo perioperatorio y periprocedimiento de la anticoagulación en la cirrosis hepática Open
View article: Inhibidores del factor XI/XIa en tromboembolia venosa esplácnica asociada a cirrosis hepatica: ¿existe algún rol potencial?
Inhibidores del factor XI/XIa en tromboembolia venosa esplácnica asociada a cirrosis hepatica: ¿existe algún rol potencial? Open
View article: Exploring the Role of Peroxisome Proliferator-Activated Receptors and Endothelial Dysfunction in Metabolic Dysfunction-Associated Steatotic Liver Disease
Exploring the Role of Peroxisome Proliferator-Activated Receptors and Endothelial Dysfunction in Metabolic Dysfunction-Associated Steatotic Liver Disease Open
The endothelium is a well known regulator of vascular homeostasis. Several factors can influence the balance of the bioavailability of active substances. This imbalance can lead to inflammation and, consequently, endothelial dysfunction, w…
View article: Exploring the Role of Peroxisome Proliferator-Activated Receptors and Endothelial Dysfunction in Metabolic Dysfunction-Associated Steatotic Liver Disease
Exploring the Role of Peroxisome Proliferator-Activated Receptors and Endothelial Dysfunction in Metabolic Dysfunction-Associated Steatotic Liver Disease Open
The endothelium is a well-known regulator of vascular homeostasis. Several factors can influence the balance of bioavailability of active substances. This imbalance can lead to inflammation and, consequently, endothelial dysfunction, which…
View article: Factors associated with obtaining lower IQR-CAP values in the detection of hepatic steatosis by transient elastography
Factors associated with obtaining lower IQR-CAP values in the detection of hepatic steatosis by transient elastography Open
In steatosis detection by CAP, obesity, significant alcohol consumption, glucose impairments, and minimal liver function test alterations were independent factors associated with non-obtaining lower values of IQR-CAP.
View article: Exploring the Role of PPARs and Endothelial Dysfunction in MASLD
Exploring the Role of PPARs and Endothelial Dysfunction in MASLD Open
Peroxisome proliferator-activated receptors (PPARs) are a family of transcription factors that belong to the superfamily of nuclear hormone receptors expressed in various tissues, with each isoform having a distinct localization and functi…
View article: Body composition differences in patients with Metabolic Dysfunction-Associated Steatotic Liver Disease
Body composition differences in patients with Metabolic Dysfunction-Associated Steatotic Liver Disease Open
Background Although body composition (BC) has been associated with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), there is little evidence of differences in BC in patients with MASLD regarding body mass index (BMI). The …
View article: Zinc supplementation in patients with cirrhosis and dysgeusia: Randomized Clinical Trial
Zinc supplementation in patients with cirrhosis and dysgeusia: Randomized Clinical Trial Open
Background: Dysgeusia has been identified as part of liver cirrhosis (LC). Since zinc (Zn) is involved in taste and LC pathophysiology, this study aimed to evaluate the effect of zinc supplementation in patients with LC. Methods: Double-bl…
View article: Predictors for liver fibrosis in non-alcoholic patients with psoriatic diseases: A multicenter cross sectional-study
Predictors for liver fibrosis in non-alcoholic patients with psoriatic diseases: A multicenter cross sectional-study Open
Psoriasis has been related to metabolic dysfunction-associated fatty liver disease and, liver fibrosis. This study aimed to evaluate the prevalence of liver fibrosis in psoriasis and identify predictors for fibrosis. This is a cross-sectio…
View article: The Relationship between Pathogenesis and Possible Treatments for the MASLD-Cirrhosis Spectrum
The Relationship between Pathogenesis and Possible Treatments for the MASLD-Cirrhosis Spectrum Open
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a term that entails a broad spectrum of conditions that vary in severity. Its development is influenced by multiple factors such as environment, microbiome, comorbidities,…
View article: Diagnostic Accuracy of the Triglyceride–Glucose Index (TyG), TyG Body Mass Index, and TyG Waist Circumference Index for Liver Steatosis Detection
Diagnostic Accuracy of the Triglyceride–Glucose Index (TyG), TyG Body Mass Index, and TyG Waist Circumference Index for Liver Steatosis Detection Open
Background: The triglyceride–glucose index (TyG) and a combination of body mass index (BMI) and waist circumference (WC) have been proposed as predictive scores for liver steatosis (LS). The aim of this study was to determine the diagnosti…
View article: O-18 DIFFERENCES IN BODY COMPOSITION OF MAFLD PATIENTS ACCORDING TO BODY MASS INDEX AND METABOLIC PROFILE
O-18 DIFFERENCES IN BODY COMPOSITION OF MAFLD PATIENTS ACCORDING TO BODY MASS INDEX AND METABOLIC PROFILE Open
Body composition (BC) has been linked to liver steatosis. The aim of this study is to describe differences in BC in MAFLD patients. Liver steatosis was evaluated by controlled attenuation parameter, patients were classified according to bo…
View article: Insulin resistance and Metabolic dysfunction-associated steatotic liver disease (MASLD): Pathways of action of hypoglycemic agents
Insulin resistance and Metabolic dysfunction-associated steatotic liver disease (MASLD): Pathways of action of hypoglycemic agents Open
Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by overweight/obesity, and the presence of type 2 diabetes mellitus is the most important criterion. We propose an independent disease perspective without ex…
View article: Prebiotics and Probiotics: Therapeutic Tools for Nonalcoholic Fatty Liver Disease
Prebiotics and Probiotics: Therapeutic Tools for Nonalcoholic Fatty Liver Disease Open
Alterations in the gut–liver axis and changes in the gut microbiome are among the risk factors for the pathogenesis of non-alcoholic fatty liver disease (NAFLD). These patients show increased bacterial overgrowth in the small intestine and…
View article: Understanding the Relationship between Nonalcoholic Fatty Liver Disease and Thyroid Disease
Understanding the Relationship between Nonalcoholic Fatty Liver Disease and Thyroid Disease Open
The prevalence of hypothyroidism in patients with nonalcoholic fatty liver disease (NAFLD) is high (22.4%). Thyroid hormones (THs) regulate many metabolic activities in the liver by promoting the export and oxidation of lipids, as well as …
View article: Hunger & satiety signals: another key mechanism involved in the NAFLD pathway
Hunger & satiety signals: another key mechanism involved in the NAFLD pathway Open
Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent metabolic disease, although prevalence could change according to region, nowadays is considered a public health problem whose real impact on the health system is unknown. NAFL…
View article: Accuracy of Narrow-Band Imaging International Colorectal Endoscopic Classification for Predicting the Histology of Colon Polyps by Experienced Endoscopists and Trainees
Accuracy of Narrow-Band Imaging International Colorectal Endoscopic Classification for Predicting the Histology of Colon Polyps by Experienced Endoscopists and Trainees Open
Narrow-Band Imaging International Colorectal Endoscopic Classification applied in the histological prediction of static images of colonic lesions has a good diagnostic performance for Narrow-Band Imaging International Colorectal Endoscopic…
View article: Systematic review and meta-analysis: Transient elastography compared to liver biopsy for staging of liver fibrosis in primary biliary cholangitis
Systematic review and meta-analysis: Transient elastography compared to liver biopsy for staging of liver fibrosis in primary biliary cholangitis Open
TE performance compared with liver biopsy in adult patients with PBC was excellent for staging liver fibrosis and was able to rule out cirrhosis in clinical practice.
View article: Low–Normal Thyroid Function Is Not Associated with Either Non-Alcoholic Fatty Liver Disease or with Metabolic Dysfunction-Associated Fatty Liver Disease
Low–Normal Thyroid Function Is Not Associated with Either Non-Alcoholic Fatty Liver Disease or with Metabolic Dysfunction-Associated Fatty Liver Disease Open
Background: The association of low–normal thyroid function (LNTF) with non-alcoholic fatty liver disease (NAFLD) or metabolic dysfunction-associated fatty liver disease (MAFLD) is controversial; thus, the aim of this study is to determine …
View article: Association between lipid profile and gallbladder histopathology of post cholecystectomy patients
Association between lipid profile and gallbladder histopathology of post cholecystectomy patients Open
Introduction: In cholelithiasis, lipid and histopathological alterations have been found and suggest the accumulation of lipids in the gallbladder tissue (cholesterolosis), due to the few existing reports a study was carried out to determi…
View article: Bariatric endoscopic-surgical therapies for NAFLD. Should they be considered viable options among current treatments?
Bariatric endoscopic-surgical therapies for NAFLD. Should they be considered viable options among current treatments? Open
Nowadays, non-alcoholic fatty liver disease is one of the first causes of liver transplant worldwide; many efforts have been done to find the perfect drug for this multifactorial disease. Presently we just have a few drugs that could be us…