Maria Beatrice Bocchi
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View article: Osteosarcoma: A Comprehensive Morphological and Molecular Review with Prognostic Implications
Osteosarcoma: A Comprehensive Morphological and Molecular Review with Prognostic Implications Open
Osteosarcoma (OS) is the most common primary malignant bone tumor, predominantly affecting adolescents and young adults. Despite advances in surgery and multi-agent chemotherapy, survival rates for metastatic or recurrent OS remain poor, h…
View article: Epidemiology and Treatment of Metastatic Lesions Around the Elbow: A Systematic Review
Epidemiology and Treatment of Metastatic Lesions Around the Elbow: A Systematic Review Open
Introduction: The elbow is a rare site for bone tumors, and for this reason, the literature provides little data on the epidemiology of metastatic lesions involving the distal humerus, proximal ulna, and radius. Before performing surgery o…
View article: Integrating vosoritide therapy with limb surgery in paediatric patients with achondroplasia: real-life experiences
Integrating vosoritide therapy with limb surgery in paediatric patients with achondroplasia: real-life experiences Open
Background Achondroplasia is the most common form of disproportionate short stature and can lead to serious medical complications, including foramen magnum and spinal stenosis. Until 2021, there were no precision treatments available, and …
View article: <scp>FPG</scp> Score: A Rapid Admission‐Based Tool for Predicting In‐Hospital Mortality in Elderly Hip Fracture Patients
<span>FPG</span> Score: A Rapid Admission‐Based Tool for Predicting In‐Hospital Mortality in Elderly Hip Fracture Patients Open
Objective Hip fractures in elderly patients are a major public health concern, associated with high morbidity and mortality. Early identification of high‐risk patients is crucial to guide clinical decision‐making, optimize resource allocat…
View article: Comparison of bilateral tibial lengthening with circular external fixator and simultaneous deformity correction with hexapod external fixator in Achondroplasia
Comparison of bilateral tibial lengthening with circular external fixator and simultaneous deformity correction with hexapod external fixator in Achondroplasia Open
Achondroplasia is a growth plate dysplasia caused by FGFR-3 gene mutation. In addition to dysmorphic short stature, genu varum is very common. Therefore, a certain part of the achondroplasic population is interested in extensive cosmetic l…
View article: Multi-Ligament Reconstruction in an Adolescent Female Affected by Congenital Femoral Deficiency and Complete Anterior and Posterior Cruciate Ligament agenesis: A Case Report
Multi-Ligament Reconstruction in an Adolescent Female Affected by Congenital Femoral Deficiency and Complete Anterior and Posterior Cruciate Ligament agenesis: A Case Report Open
Purpose: Multi-ligament reconstruction in adolescent patients affected by congenital femoral deficiency is an extremely rare and delicate surgical procedure. There are very few reported cases of complete anterior and posterior cruciate lig…
View article: Multi-Ligament Reconstruction in an Adolescent Female Affected by Congenital Femoral Deficiency and Complete Anterior and Posterior Cruciate Ligament Agenesis: A Case Report
Multi-Ligament Reconstruction in an Adolescent Female Affected by Congenital Femoral Deficiency and Complete Anterior and Posterior Cruciate Ligament Agenesis: A Case Report Open
Background Multi-ligament reconstruction in adolescent patients affected by congenital femoral deficiency is an extremely rare and delicate surgical procedure. There are very few reported cases of complete anterior and posterior cruciate l…
View article: Roles and Applications of Circulating Tumor-Derived RNAs in Sarcoma Patients: A Systematic Review
Roles and Applications of Circulating Tumor-Derived RNAs in Sarcoma Patients: A Systematic Review Open
Sarcomas are a heterogeneous group of malignancies with a high mortality rate. Detection of circulating tumor-derived material, such as circulating RNA in the peripheral blood of patients, has shown to be useful in diagnosis, prediction of…
View article: Characteristics and Epidemiology of Megaprostheses Infections: A Systematic Review
Characteristics and Epidemiology of Megaprostheses Infections: A Systematic Review Open
Background: Megaprostheses were first employed in oncological orthopedic surgery, but more recently, additional applications have arisen. These implants are not without any risks and device failure is quite frequent. The most feared compli…
View article: Pathological Fractures in Patients Affected by Pycnodysostosis: A Case Series
Pathological Fractures in Patients Affected by Pycnodysostosis: A Case Series Open
Background/Objectives: Pycnodysostosis is a rare genetic disorder causing skeletal dysplasia. It is determined by a gene mutation leading to cathepsin K deficiency and predisposes a patient to osteosclerosis, resulting in increased bone fr…
View article: Epidemiology and Treatment of Surgical Infection after Ankle Arthroscopy: A Systematic Review
Epidemiology and Treatment of Surgical Infection after Ankle Arthroscopy: A Systematic Review Open
Background: Ankle arthroscopy is indicated for both diagnosis and treatment of a large spectrum of common ankle disorders. It has certain advantages over the open procedure; however, it is important to recognize that there are some complic…
View article: Electrochemotherapy in the Treatment of Bone Metastases: A Systematic Review
Electrochemotherapy in the Treatment of Bone Metastases: A Systematic Review Open
Background and aim: Cancers are one of the most frequent causes of death and disability in humans. Skeletal involvement has a major impact on the quality of life and prognosis of cancer patients. Electrochemotherapy is a palliative and min…
View article: Short-segment percutaneous fusion versus open posterior fusion with screw in the fractured vertebra for thoracolumbar junction burst vertebral fracture treatment
Short-segment percutaneous fusion versus open posterior fusion with screw in the fractured vertebra for thoracolumbar junction burst vertebral fracture treatment Open
Objectives: The treatment options for thoracolumbar junction burst fractures remain a topic of controversy. Short-segment percutaneous fixation (SSPF) and short-segment open fixation including the fractured level (SSOFIFL) are both viable …
View article: Surgical treatment, complications and preventive surgery of fractures in pycnodysostosis: a systematic review
Surgical treatment, complications and preventive surgery of fractures in pycnodysostosis: a systematic review Open
Background: Pycnodysostosis (PYCD) is a rare genetic disorder causing skeletal dysplasia. It is inherited in an autosomal recessive manner, and it is caused by a gene mutation leading cathepsin K (CTSK) deficiency. PYCD is characterized am…
View article: Limb lengthening with PRECICE magnetic nail in pediatric patients: A systematic review
Limb lengthening with PRECICE magnetic nail in pediatric patients: A systematic review Open
This review shows that the PRECICE Nail System is still a therapeutic challenge in limb lengthening for pediatric orthopedic surgeons; however, careful pre-operative planning and an accurate surgical technique could allow the correction of…
View article: Correction of a severe coronal malalignment in adult spinal deformity using the “kickstand rod” technique as primary surgery
Correction of a severe coronal malalignment in adult spinal deformity using the “kickstand rod” technique as primary surgery Open
View article: Early loss of angular kyphosis correction in patients with thoracolumbar vertebral burst (A3-A4) fractures who underwent percutaneous pedicle screws fixation
Early loss of angular kyphosis correction in patients with thoracolumbar vertebral burst (A3-A4) fractures who underwent percutaneous pedicle screws fixation Open
View article: Bone metastases in lung cancer
Bone metastases in lung cancer Open
As lung cancer is the most common neoplasm worldwide, bone is one of the most metastatic sites of advanced malignant tumors in general. Nearly 50% of patients with advanced lung cancer develop bone metastases. A literature review on this m…
View article: A rare case of Bacillus megaterium soft tissues infection.
A rare case of Bacillus megaterium soft tissues infection. Open
The histological report tested negative for osteomyelitis. Bacterial cultures revealed Bacillus megaterium, which was sensitive to all antibiotics against which it was tested. The oral antibiotic therapy was set for 12 days with benefits. …
View article: Posterior thoracolumbar fusion in a patient with Kleefstra Syndrome related scoliosis: The first case reported
Posterior thoracolumbar fusion in a patient with Kleefstra Syndrome related scoliosis: The first case reported Open
View article: Bifocal parosteal osteoma of femur: A case report and review of literature
Bifocal parosteal osteoma of femur: A case report and review of literature Open
Osteoma is a benign, slowly growing, asymptomatic, bone-forming tumor arising from cancellous or compact bone. Osteoma usually is a solitary lesion, but in patients with Gardner’s Syndrome it may be multiple. osteoma may rarely have a paro…
View article: Foot metastasis: Current knowledge
Foot metastasis: Current knowledge Open
Foot metastasis are rare and often overlooked due to non-specifical symptoms. This often leads to misdiagnosis delaying the right diagnosis. Metastatic disease of the foot is rare. Foot pain and swelling may be the presenting symptom of an…
View article: Arthrodesis in the Charcot foot: a systematic review
Arthrodesis in the Charcot foot: a systematic review Open
The Charcot foot is a condition characterized by a progressive derangement of the foot. The type of deformity and patient clinical conditions will lead to the proper surgical approach among exostectomy, arthrodesis (through external and/or…