Maria Cássia Mendes-Corrêa
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View article: Circulation of Herpesvirus and Alphatorquevirus DNA in each trimester in asymptomatic women pregnant with twins
Circulation of Herpesvirus and Alphatorquevirus DNA in each trimester in asymptomatic women pregnant with twins Open
Background Data on the dynamics of Herpesviruses and Torque teno virus (TTV) in plasma from twin pregnancies are limited, despite their potential to provide insights into maternal immune status in this high-risk population. Methods A conve…
View article: Prevalence and risk factors for dengue virus infection and malaria among febrile patients in Anambra State, Nigeria, 2024
Prevalence and risk factors for dengue virus infection and malaria among febrile patients in Anambra State, Nigeria, 2024 Open
Introduction Dengue virus and malaria parasites are mosquito-borne pathogens causing febrile illness among people in tropical and subtropical regions. Dengue, often misdiagnosed as malaria, is an epidemic-prone disease in over 90 countries…
View article: A Comprehensive Molecular and Serological Investigation of Hepatitis A Virus Among Patients With Suspected Acute Hepatitis: A Brazilian Study
A Comprehensive Molecular and Serological Investigation of Hepatitis A Virus Among Patients With Suspected Acute Hepatitis: A Brazilian Study Open
Hepatitis A Virus (HAV) infects millions of individuals annually and is a major cause of acute viral hepatitis worldwide. This study aims to (1) assess HAV infection in suspected acute hepatitis patients at public healthcare institutions i…
View article: Metagenomic detection of central nervous system infections missedby conventional testing
Metagenomic detection of central nervous system infections missedby conventional testing Open
Community-acquired infectious meningoencephalitis is associated with high rates of mortality and morbidity, compounded by limited access to diagnostic resources. The current study assessed acute central nervous system (CNS) infections in p…
View article: Phylogenetic Analysis of Varicella–Zoster Virus in Cerebrospinal Fluid from Individuals with Acute Central Nervous System Infection: An Exploratory Study
Phylogenetic Analysis of Varicella–Zoster Virus in Cerebrospinal Fluid from Individuals with Acute Central Nervous System Infection: An Exploratory Study Open
Background: There is scarce information on Varicella–Zoster virus genetic variability in individuals with acute central nervous system infection in Brazil. The objective of this study was the molecular characterization of Varicella–Zoster …
View article: Viruses in the female lower reproductive tract: a systematic descriptive review of metagenomic investigations
Viruses in the female lower reproductive tract: a systematic descriptive review of metagenomic investigations Open
The lower female reproductive tract (FRT) hosts a complex microbial environment, including eukaryotic and prokaryotic viruses (the virome), whose roles in health and disease are not fully understood. This review consolidates findings on FR…
View article: Corrigendum to: Novel members of the order Picornavirales identified in freshwater from Guarapiranga reservoir in São Paulo (infection, Genetics and Evolution Volume 124, October 2024, 105668)
Corrigendum to: Novel members of the order Picornavirales identified in freshwater from Guarapiranga reservoir in São Paulo (infection, Genetics and Evolution Volume 124, October 2024, 105668) Open
View article: First Detection and Characterization of Smacovirus in the Human Vagina in Two Sequential Samples over a Twelve-Day Interval
First Detection and Characterization of Smacovirus in the Human Vagina in Two Sequential Samples over a Twelve-Day Interval Open
Background: Smacovirus is a CRESS-DNA virus identified almost exclusively in transient fecal samples from various vertebrate species. Objective: We evaluated human vaginal samples for the presence and maintenance of Smacovirus. Methods: Vi…
View article: Characterization of multiple human papillomavirus types in the human vagina following ovarian hormonal stimulation
Characterization of multiple human papillomavirus types in the human vagina following ovarian hormonal stimulation Open
View article: Novel members of the order Picornavirales identified in freshwater from Guarapiranga reservoir in São Paulo
Novel members of the order Picornavirales identified in freshwater from Guarapiranga reservoir in São Paulo Open
The global challenge of water resource availability is exacerbated by anthropogenic influences that promote the emergence of pollutants. Among these pollutants are microbiological agents, including viruses, which are ubiquitous in the bios…
View article: Dissecting the ocular impact of SARS-CoV-2 variants: Analysis of eye globe and retina in animal models
Dissecting the ocular impact of SARS-CoV-2 variants: Analysis of eye globe and retina in animal models Open
Neurological and ocular manifestations were reported in COVID-19 patients and in SARS-CoV-2 infected animal models. However, the effects of SARS-CoV-2 variants of concern (VoC) on the eyes and the retina remain unclear. Here, we investigat…
View article: Ocular manifestations of Monkeypox virus (MPXV) infection with viral persistence in ocular samples: A case series
Ocular manifestations of Monkeypox virus (MPXV) infection with viral persistence in ocular samples: A case series Open
This study reveals a late onset and persistence of sight threatening ocular disease, along with potential viral infectivity even after systemic resolution in mpox cases. These findings highlight the risk of ongoing transmission from indivi…
View article: Data-driven, cross-disciplinary collaboration: lessons learned at the largest academic health center in Latin America during the COVID-19 pandemic
Data-driven, cross-disciplinary collaboration: lessons learned at the largest academic health center in Latin America during the COVID-19 pandemic Open
Introduction The COVID-19 pandemic has prompted global research efforts to reduce infection impact, highlighting the potential of cross-disciplinary collaboration to enhance research quality and efficiency. Methods At the FMUSP-HC academic…
View article: Seroprevalence of hepatitis B, C, and D and associated factors in the semi-isolated Yanomami Amazonian indigenous community
Seroprevalence of hepatitis B, C, and D and associated factors in the semi-isolated Yanomami Amazonian indigenous community Open
View article: SARS-CoV-2 shedding, infectivity, and evolution in an immunocompromised adult patient
SARS-CoV-2 shedding, infectivity, and evolution in an immunocompromised adult patient Open
This study aimed to provide further insight into the evolutionary dynamics of SARS-CoV-2 by analyzing the case of a 40-year-old man who had previously undergone autologous hematopoietic stem cell transplantation due to a diffuse large B-ce…
View article: Prevalence and clinical consequences of Hepatitis C virus infection in patients undergoing hematopoietic stem cell transplantation
Prevalence and clinical consequences of Hepatitis C virus infection in patients undergoing hematopoietic stem cell transplantation Open
Hepatitis C virus (HCV) infection is a significant cause of morbidity and mortality among hematopoietic stem cell transplant (HCT) recipients. In Brazil, its occurrence in HCT recipients remains undetermined. We now report on HCV prevalenc…
View article: A critical evaluation of the status of HPV vaccination in São Paulo State, Brazil
A critical evaluation of the status of HPV vaccination in São Paulo State, Brazil Open
View article: Characterization of Multiple Human Papillomavirus Types in the Human Vagina Following Ovarian Hormonal Stimulation
Characterization of Multiple Human Papillomavirus Types in the Human Vagina Following Ovarian Hormonal Stimulation Open
View article: Adjusted estimate of the prevalence of hepatitis delta virus in 25 countries and territories
Adjusted estimate of the prevalence of hepatitis delta virus in 25 countries and territories Open
View article: Intranasal Liposomal Formulation of Spike Protein Adjuvanted with CpG Protects and Boosts Heterologous Immunity of hACE2 Transgenic Mice to SARS-CoV-2 Infection
Intranasal Liposomal Formulation of Spike Protein Adjuvanted with CpG Protects and Boosts Heterologous Immunity of hACE2 Transgenic Mice to SARS-CoV-2 Infection Open
Mucosal vaccination appears to be suitable to protect against SARS-CoV-2 infection. In this study, we tested an intranasal mucosal vaccine candidate for COVID-19 that consisted of a cationic liposome containing a trimeric SARS-CoV-2 spike …
View article: SARS-CoV-2 lineage-specific disease symptoms and disease severity in São Caetano do Sul city, Brazil
SARS-CoV-2 lineage-specific disease symptoms and disease severity in São Caetano do Sul city, Brazil Open
Background The city of São Caetano do Sul, Brazil, established a web-based platform to provide primary care to suspected COVID-19 patients, integrating clinical and demographic data and sample metadata. Here we describe lineage-specific sp…
View article: Association between torquetenovirus in vaginal secretions and infertility: An exploratory metagenomic analysis
Association between torquetenovirus in vaginal secretions and infertility: An exploratory metagenomic analysis Open
Problem The association of viruses with infertility remains incompletely evaluated. Method of study Vaginal secretions from 46 women seeking treatment in the Center for Reproductive Medicine and Infertility at Weill Cornell Medicine were t…
View article: Intranasal Liposomal Formulation of Spike Protein Adjuvanted with CpG Protects and Boosts Heterologous Immunity of hACE2 Transgenic Mice to SARS-CoV-2 Infection
Intranasal Liposomal Formulation of Spike Protein Adjuvanted with CpG Protects and Boosts Heterologous Immunity of hACE2 Transgenic Mice to SARS-CoV-2 Infection Open
Mucosal vaccination appears to be suitable to protect against SARS-CoV-2 infection. In this study, we tested an intranasal mucosal vaccine candidate to COVID-19 constituted of a cationic liposome containing a trimeric SARS-CoV-2 spike prot…
View article: Survival analysis over a 20-year period of a Brazilian cohort of blood donors coinfected HIV-HCV
Survival analysis over a 20-year period of a Brazilian cohort of blood donors coinfected HIV-HCV Open
View article: Detailed characterization of Redondovirus in saliva of SARS-CoV-2-infected individuals in Sao Paulo, Brazil
Detailed characterization of Redondovirus in saliva of SARS-CoV-2-infected individuals in Sao Paulo, Brazil Open
Background Redondovirus (ReDoV) is a DNA virus present in the respiratory tract of many healthy individuals. Since SARS-CoV-2, the virus responsible for COVID-19, also primarily infects the same site, we evaluated whether ReDoV was present…
View article: Encephalopathy Caused by Human Parvovirus B19 Genotype 1 Associated with Haemophilus influenzae Meningitis in a Newborn
Encephalopathy Caused by Human Parvovirus B19 Genotype 1 Associated with Haemophilus influenzae Meningitis in a Newborn Open
Parvovirus B19 infection is associated with a wide range of clinical manifestations, from asymptomatic to severe neurological disorders. Its major clinical symptoms, fever and rash, are common to multiple viruses, and laboratory tests to d…
View article: Characterization of Torquetenovirus in amniotic fluid at the time of in utero fetal surgery: correlation with early premature delivery and respiratory distress
Characterization of Torquetenovirus in amniotic fluid at the time of in utero fetal surgery: correlation with early premature delivery and respiratory distress Open
Torquetenovirus (TTV) is a commensal virus present in many healthy individuals. Although considered to be non-pathogenic, its presence and titer have been shown to be indicative of altered immune status in individuals with chronic infectio…
View article: Association between development of severe COVID-19 and a polymorphism in the CIAS1 gene that codes for an inflammasome component
Association between development of severe COVID-19 and a polymorphism in the CIAS1 gene that codes for an inflammasome component Open
View article: SARS-CoV-2 Detection and Culture in Different Biological Specimens from Immunocompetent and Immunosuppressed COVID-19 Patients Infected with Two Different Viral Strains
SARS-CoV-2 Detection and Culture in Different Biological Specimens from Immunocompetent and Immunosuppressed COVID-19 Patients Infected with Two Different Viral Strains Open
Introduction—The dynamics of SARS-CoV-2 shedding and replication in humans remain incompletely understood. Methods—We analyzed SARS-CoV-2 shedding from multiple sites in individuals with an acute COVID-19 infection by weekly sampling for f…
View article: Encephalopathy Caused by Human Parvovirus B19 Genotype 1 Associated With Haemophilus influenzae Meningitis in a Newborn
Encephalopathy Caused by Human Parvovirus B19 Genotype 1 Associated With Haemophilus influenzae Meningitis in a Newborn Open
Parvovirus B19 infection is associated with a wide range of clinical manifestations, from asymp-tomatic to severe neurological disorders. Its major clinical symptoms, fever and rash, are com-mon to multiple viruses, and laboratory tests to…