Rossella Marcucci
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View article: Sleep Irregularity and Short Sleep Duration Are Associated with Less Favorable Cardiometabolic Profiles in Healthy Adults: A Cross-Sectional Study
Sleep Irregularity and Short Sleep Duration Are Associated with Less Favorable Cardiometabolic Profiles in Healthy Adults: A Cross-Sectional Study Open
Background/Objectives: The aim of this study is to evaluate the relation between sleep quantity (TST), efficiency (SE) and regularity (SRI) and cardiometabolic parameters and eating habits. Methods: Seventy clinically healthy adults (74% f…
View article: Persistence of functional anti-PF4 antibodies and neutrophil activation in vaccine-induced immune thrombotic thrombocytopenia
Persistence of functional anti-PF4 antibodies and neutrophil activation in vaccine-induced immune thrombotic thrombocytopenia Open
Background: Vaccine-induced immune thrombotic thrombocytopenia (VITT) is characterized by thrombosis in unusual sites triggered by anti-PF4 antibodies. To the best of our knowledge, no studies with very long follow-up on anti-PF4 antibodie…
View article: Real-world use of direct oral anticoagulants in atrial fibrillation patients with moderate/severe chronic kidney disease: a propensity score matched analysis from the START registry
Real-world use of direct oral anticoagulants in atrial fibrillation patients with moderate/severe chronic kidney disease: a propensity score matched analysis from the START registry Open
Background Chronic kidney disease (CKD) often coexists in patients with atrial fibrillation (AF), worsening patients’ prognosis. Direct oral anticoagulants (DOACs) are increasingly used also in patients with AF and CKD, but limited evidenc…
View article: Trousseau’s Syndrome and Marantic Endocarditis in a Patient with Pulmonary Adenocarcinoma: A Case Report and a Brief Review of the Literature
Trousseau’s Syndrome and Marantic Endocarditis in a Patient with Pulmonary Adenocarcinoma: A Case Report and a Brief Review of the Literature Open
Background and Clinical Significance: Trousseau’s syndrome, characterized by recurrent thromboembolic events and non-bacterial thrombotic endocarditis, represents a severe paraneoplastic condition associated with poor prognosis in cancer p…
View article: Comparative analysis of upper labial frenulum surgical techniques: from scalpel to laser
Comparative analysis of upper labial frenulum surgical techniques: from scalpel to laser Open
The upper labial frenulum (ULF) is a connective tissue band that can significantly impact oral function and aesthetics when hypertrophic or abnormally positioned. This review examines surgical techniques for managing ULF, comparing traditi…
View article: Effects of a Probiotic Formulation Based on SF68, Phytosterols, and 6S‐5‐Methyltetrahydrofolic Acid on Body Composition, Biochemical Parameters, Gut Microbiota, and Gastrointestinal and General Symptoms of Overweight/Obese Subjects: The PrObesity Study
Effects of a Probiotic Formulation Based on SF68, Phytosterols, and 6S‐5‐Methyltetrahydrofolic Acid on Body Composition, Biochemical Parameters, Gut Microbiota, and Gastrointestinal and General Symptoms of Overweight/Obese Subjects: The PrObesity Study Open
Obesity and dyslipidemia are increasingly widespread. Considering gut microbiota's (GM) role in energy balance, probiotics represent a promising non‐pharmacological approach. This study assessed a probiotic formulation (SF68 + phytosterols…
View article: Prolonged Hematogone Expansion Is Associated with Better Outcomes in Allogeneic Hematopoietic Stem Cell Transplantation Recipients
Prolonged Hematogone Expansion Is Associated with Better Outcomes in Allogeneic Hematopoietic Stem Cell Transplantation Recipients Open
Background/Objectives: Hematogones, B cell precursors, are considered a clock of bone marrow reconstitution after chemotherapy and hematopoietic stem cell transplantation (HSCT). Methods: In this retrospective observational monocentric stu…
View article: Ischaemic Stroke in Patients with Known Atrial Fibrillation: A Snapshot from a Large University Hospital Experience
Ischaemic Stroke in Patients with Known Atrial Fibrillation: A Snapshot from a Large University Hospital Experience Open
Objectives: Atrial fibrillation (AF) is associated with high risk of ischaemic stroke (IS). Oral anticoagulant therapy (OAT) is the standard of care for stroke prevention, even though its management remains challenging in clinical practice…
View article: Long-term outcome of tailored antithrombotic therapy based on platelet function testing in patients undergoing percutaneous coronary intervention: a 5-year retrospective cohort study
Long-term outcome of tailored antithrombotic therapy based on platelet function testing in patients undergoing percutaneous coronary intervention: a 5-year retrospective cohort study Open
Dual antiplatelet therapy is the standard therapy for the secondary prevention of acute and chronic coronary syndromes in patients undergoing percutaneous coronary intervention (PCI). The introduction of more potent antiplatelet agents and…
View article: Trousseau’s Syndrome and Marantic Endocarditis in a Patient with Pulmonary Adenocarcinoma: A Case Report and Review of Literature
Trousseau’s Syndrome and Marantic Endocarditis in a Patient with Pulmonary Adenocarcinoma: A Case Report and Review of Literature Open
Background: Trousseau’s syndrome, characterized by recurrent thromboembolic events and non-bacterial thrombotic endocarditis, represents a severe paraneoplastic condition associated with poor prognosis in cancer patients. Methods: We descr…
View article: Thrombotic events after vaccination for covid-19 in Italy: a report from the Italian society on thrombosis and haemostasis registry
Thrombotic events after vaccination for covid-19 in Italy: a report from the Italian society on thrombosis and haemostasis registry Open
Since vaccine induced immune thrombotic thrombocytopenia (VITT) became evident in early 2021, research has focused on characterizing this new pathologic entity. Moreover, data were urgently needed on the association, if any, between all CO…
View article: Pleiotropic Effects of Oral Anticoagulant Therapy: Is There a Difference Between VKAs and DOACs?
Pleiotropic Effects of Oral Anticoagulant Therapy: Is There a Difference Between VKAs and DOACs? Open
Background: Atrial fibrillation (AF) is one of the most common heart rhythm disorders encountered in clinical practice. Emerging evidence suggests a significant role of inflammation in the pathogenesis of AF, but certain questions still re…
View article: The role of dyslipidemia and gender-related risk factors in the management of patients with abdominal aortic aneurysms: a survey from the Italian Society of Angiology and Vascular Medicine and a call to action
The role of dyslipidemia and gender-related risk factors in the management of patients with abdominal aortic aneurysms: a survey from the Italian Society of Angiology and Vascular Medicine and a call to action Open
Background: abdominal aortic aneurysm (AAA) affects 1-3% of adults and carries a high fatality rate if ruptured. Although it is more common in men, women tend to have worse outcomes. Screening high-risk individuals is cost-effective, and l…
View article: PCSK9-Targeting Drugs and Gender: Are There Any Differences?
PCSK9-Targeting Drugs and Gender: Are There Any Differences? Open
Background: Atherosclerotic cardiovascular disease (ASCVD) is often perceived as a male-dominant condition, yet recent European data show that more women live with and die from it. Gender disparities have been reported in the management of…
View article: Atrial Fibrillation, Heart Failure Phenotypes, and Mortality Risk in the Nationwide START Registry: A Propensity Score Matching Analysis
Atrial Fibrillation, Heart Failure Phenotypes, and Mortality Risk in the Nationwide START Registry: A Propensity Score Matching Analysis Open
Background Data on atrial fibrillation (AF) and heart failure (HF) with preserved ejection fraction (HFpEF) are scarce. We investigated the association of HFpEF with all‐cause mortality in AF. Methods We included 10 369 patients with AF on…
View article: Sex‐specific predictive value of reticulated platelets in coronary artery disease: A systematic review and meta‐analysis
Sex‐specific predictive value of reticulated platelets in coronary artery disease: A systematic review and meta‐analysis Open
Background Platelets play a crucial role in immune responses and haemostasis. Among them, reticulated platelets (RPs) have gathered attention for their association with prothrombotic states and as a potential biomarker for cardiovascular e…
View article: CD38 prognostic role in chronic lymphocytic leukemia patients treated with standard chemotherapy or targeted agents: a monocentric real-life experience
CD38 prognostic role in chronic lymphocytic leukemia patients treated with standard chemotherapy or targeted agents: a monocentric real-life experience Open
Introduction Therapeutic strategies for patients affected by Chronic Lymphocytic Leukemia (CLL) have undergone significant changes over the last decade, shifting from chemoimmunotherapy to targeted therapy. Methods This retrospective, sing…
View article: The impact of the timing of pasta intake on sleep quality and health outcomes: a protocol for a randomized controlled trial
The impact of the timing of pasta intake on sleep quality and health outcomes: a protocol for a randomized controlled trial Open
ClinicalTrials.gov NCT06185634. Registered on 07/01/2024.
View article: The Impact of the Timing of Pasta Intake on Sleep Quality and Health Outcomes: A Protocol for a Randomized Controlled Trial
The Impact of the Timing of Pasta Intake on Sleep Quality and Health Outcomes: A Protocol for a Randomized Controlled Trial Open
Background: Pasta is a fundamental component of the Mediterranean diet and a key source of carbohydrates. Despite its nutritional benefits, misconceptions persist regarding its potential to promote weight gain, particularly when consumed a…
View article: Markers of Inflammation and Hypofibrinolysis Are Associated with Cognitive Dysfunction and Motor Performances in Atrial Fibrillation Patients on Oral Anticoagulant Therapy: Insights from the Strat-AF Study
Markers of Inflammation and Hypofibrinolysis Are Associated with Cognitive Dysfunction and Motor Performances in Atrial Fibrillation Patients on Oral Anticoagulant Therapy: Insights from the Strat-AF Study Open
Background: Atrial fibrillation (AF) is the most common supraventricular arrythmia and one of the most commonly encountered heart conditions in clinical practice. Emerging evidence suggests a significant role of inflammation in the pathoge…
View article: Clinical and echocardiographic predictors of postoperative atrial fibrillation in lung surgery: the role of left atrial remodelling
Clinical and echocardiographic predictors of postoperative atrial fibrillation in lung surgery: the role of left atrial remodelling Open
Postoperative atrial fibrillation (PoAF) complicates 10–15% of pulmonary lobectomy and 20–30% of pneumonectomy, contributing to increased morbidity, extended hospital stays, and healthcare costs. Identifying predictors of PoAF may aid in r…
View article: “Keep HIT in Mind and Take Care”. Multiple Tips From a Single Patient
“Keep HIT in Mind and Take Care”. Multiple Tips From a Single Patient Open
HIT should always be kept in mind after cardiac surgery, even if a more plausible cause of thrombocytopenia is present. Discontinuation of warfarin could lead to catastrophic consequences if an unrecognized HIT is ongoing, and an alternati…
View article: Real-World Efficacy and Safety of Inclisiran
Real-World Efficacy and Safety of Inclisiran Open
Italian register of patients treated with inclisiran. real world dataon efficacy and safety
View article: Association of human leucocyte antigen loci with vaccine‐induced immune thrombotic thrombocytopenia: Potential role of the interaction between platelet factor 4‐derived peptides and <scp>MHC</scp>‐<scp>II</scp>
Association of human leucocyte antigen loci with vaccine‐induced immune thrombotic thrombocytopenia: Potential role of the interaction between platelet factor 4‐derived peptides and <span>MHC</span>‐<span>II</span> Open
Summary No risk factors have been identified for vaccine‐induced immune thrombotic thrombocytopenia (VITT) so far. The aim of this study was to identify human leucocyte antigen (HLA) alleles potentially associated with VITT susceptibility.…
View article: Emerging Thrombotic Disorders Associated with Virus-Based Innovative Therapies: From VITT to AAV Gene Therapy–Related Thrombotic Microangiopathy
Emerging Thrombotic Disorders Associated with Virus-Based Innovative Therapies: From VITT to AAV Gene Therapy–Related Thrombotic Microangiopathy Open
Gene therapy is a promising therapeutic approach for treating life-threatening disorders. Despite the clinical improvements observed with gene therapy, immune responses either innate or adaptive against the vector used for gene delivery, c…