María Camila Jiménez
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View article: MON-283 Rhabdomyolysis In A Patient With Primary Hyperaldosteronism: A Clinical Challenge
MON-283 Rhabdomyolysis In A Patient With Primary Hyperaldosteronism: A Clinical Challenge Open
Disclosure: M. Lizarazo Jimenez: None. Y. Rodriguez: None. D. Soto Camargo: None. A. Florez: None. L. Kattah Martinez: None. L. Bustamante Gómez: None. Introduction: Rhabdomyolysis is an uncommon but potentially life-threatening complicati…
View article: Petiveria alliacea and Caesalpinia spinosa extracts reduce the generation of cancer-associated fibroblasts in a 3D platform representative of the tumor microenvironment
Petiveria alliacea and Caesalpinia spinosa extracts reduce the generation of cancer-associated fibroblasts in a 3D platform representative of the tumor microenvironment Open
We found that the two extracts interfere with circuits that drive tumor-fibroblast crosstalk, attenuating the phenotype and functional activities associated with CAFs in this TME model.
View article: Triple negative breast cancer migration is modified by mitochondrial metabolism alteration induced by natural extracts of C. spinosa and P. alliacea
Triple negative breast cancer migration is modified by mitochondrial metabolism alteration induced by natural extracts of C. spinosa and P. alliacea Open
Tumor metabolism is a crucial aspect of cancer development, and mitochondria plays a significant role in the aggressiveness and metastasis of tumors. As a result, mitochondria have become a promising therapeutic target in cancer treatment,…
View article: Tillandsia usneoides Ethanolic Extract Induces Cytotoxicity in SW480 Colon Cancer Cell Line via PPARγ Modulation
Tillandsia usneoides Ethanolic Extract Induces Cytotoxicity in SW480 Colon Cancer Cell Line via PPARγ Modulation Open
Colorectal cancer (CRC) is a prevalent and deadly tumor worldwide. Understanding the molecular mechanisms underlying CRC development will improve treatment outcomes and patient survival. Natural molecules and metabolites from plants, such …
View article: The secretome from human-derived mesenchymal stem cells augments the activity of antitumor plant extracts in vitro
The secretome from human-derived mesenchymal stem cells augments the activity of antitumor plant extracts in vitro Open
Cancer is understood as a multifactorial disease that involve multiple cell types and phenotypes in the tumor microenvironment (TME). The components of the TME can interact directly or via soluble factors (cytokines, chemokines, growth fac…
View article: Plant extract from Caesalpinia spinosa inhibits cancer-associated fibroblast-like cells generation and function in a tumor microenvironment model
Plant extract from Caesalpinia spinosa inhibits cancer-associated fibroblast-like cells generation and function in a tumor microenvironment model Open
Interactions in the tumor microenvironment (TME) between tumor cells and stromal cells such as cancer-associated fibroblasts (CAF) favor increased survival, progression, and transformation of cancer cells by activating mechanisms of invasi…
View article: Plant Extract from Caesalpinia Spinosa Inhibits Cancer-Associated Fibroblast-Like Cells Generation and Function in a Tumor Microenvironment Model
Plant Extract from Caesalpinia Spinosa Inhibits Cancer-Associated Fibroblast-Like Cells Generation and Function in a Tumor Microenvironment Model Open
View article: Enfermedad hemolítica del feto y del recién nacido por aloanticuerpos contra el antígeno M
Enfermedad hemolítica del feto y del recién nacido por aloanticuerpos contra el antígeno M Open
Hay pocos reportes de enfermedad hemolítica del feto y del recién nacido causada por aloanticuerpos contra el sistema de antígenos MNS, especialmente, porque los anticuerpos que se generan contra estos antígenos son del tipo IgM, los cuale…
View article: Clinical Features Associated with Female Genital Mutilation/Cutting: A Pilot Longitudinal Study
Clinical Features Associated with Female Genital Mutilation/Cutting: A Pilot Longitudinal Study Open
(1) Background: Female genital mutilation/cutting (FGM/C) is associated with physical and psychological complications. However, there is scarce literature on how women with FGM/C respond to treatment interventions. (2) Methods: In the pres…
View article: Generation of Organotypic Multicellular Spheres by Magnetic Levitation: Model for the Study of Human Hematopoietic Stem Cells Microenvironment
Generation of Organotypic Multicellular Spheres by Magnetic Levitation: Model for the Study of Human Hematopoietic Stem Cells Microenvironment Open
We developed organotypic multicellular spheres from normal human cells that mimic the microenvironment of the human hematopoietic stem cells. These structures are the prototype for the development of complex organoids that allow the furthe…