Marco A. Zago
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View article: Mitral insufficiency: a comparative study on techniques for mitral valvuloplasty
Mitral insufficiency: a comparative study on techniques for mitral valvuloplasty Open
Mitral insufficiency (MI), also known as mitral regurgitation, is a clinical condition characterized by the inadequate closure of the mitral valve during systole, resulting in the backflow of blood from the left ventricle to the left atriu…
View article: Genetic variation among major human geographic groups supports a peculiar evolutionary trend in PAX9
Genetic variation among major human geographic groups supports a peculiar evolutionary trend in PAX9 Open
A total of 172 persons from nine South Amerindian, three African and one Eskimo populations were studied in relation to the Paired box gene 9 (PAX9) exon 3 (138 base pairs) as well as its 59and 39flanking intronic segments (232 bp and 220 …
View article: ETV4 plays a role on the primary events during the adenoma-adenocarcinoma progression in colorectal cancer
ETV4 plays a role on the primary events during the adenoma-adenocarcinoma progression in colorectal cancer Open
Background Colorectal cancer (CRC) is one of the most common cancers worldwide; it is the fourth leading cause of death in the world and the third in Brazil. Mutations in the APC, DCC, KRAS and TP53 genes have been associated with the prog…
View article: A High-Content Screening Approach to Identify MicroRNAs Against Head and Neck Cancer Cell Survival and EMT in an Inflammatory Microenvironment
A High-Content Screening Approach to Identify MicroRNAs Against Head and Neck Cancer Cell Survival and EMT in an Inflammatory Microenvironment Open
Head and neck squamous cell carcinoma (HNSCC) is among the most common cancer types. Metastasis, the main cause of death by cancer, can be promoted by an inflammatory microenvironment, which induces epithelial-mesenchymal transition (EMT) …
View article: Additional file 5: of High-content screen in human pluripotent cells identifies miRNA-regulated pathways controlling pluripotency and differentiation
Additional file 5: of High-content screen in human pluripotent cells identifies miRNA-regulated pathways controlling pluripotency and differentiation Open
Pathways comparisons. Excel file with all comparisons between the pathways identified by DAVID. (XLSX 31 kb)
View article: Additional file 4: of High-content screen in human pluripotent cells identifies miRNA-regulated pathways controlling pluripotency and differentiation
Additional file 4: of High-content screen in human pluripotent cells identifies miRNA-regulated pathways controlling pluripotency and differentiation Open
DAVID pathways analysis. Excel file with all results from the enrichment pathway analyses carried using DAVID. (XLSX 163 kb)
View article: Expression of cancer/testis antigens MAGE‑A, MAGE‑C1, GAGE and CTAG1B in benign and malignant thyroid diseases
Expression of cancer/testis antigens MAGE‑A, MAGE‑C1, GAGE and CTAG1B in benign and malignant thyroid diseases Open
Despite considerable advances in the understanding of thyroid gland biology, correctly diagnosing thyroid nodules and treating high-grade thyroid carcinoma remains challenging. Cancer/testis (CT) antigens have emerged as potential diagnost…
View article: Impact of CTLA4 genotype and other immune response gene polymorphisms on outcomes after single umbilical cord blood transplantation
Impact of CTLA4 genotype and other immune response gene polymorphisms on outcomes after single umbilical cord blood transplantation Open
Key Points Gene polymorphism of the immune response as CTLA4 was shown to impact CBT outcomes according to CBU genotype. CTLA4-CBU genotype might be considered for CBU selection when >1 CBU meeting the current suggested selection criteria …
View article: Association of the solute carrier family 11 member 1 gene polymorphisms with susceptibility to leprosy in a Brazilian sample
Association of the solute carrier family 11 member 1 gene polymorphisms with susceptibility to leprosy in a Brazilian sample Open
Natural resistance-associated macrophage protein 1/solute carrier family 11 member 1 gene (Nramp1/Slc11a1) is a gene that controls the susceptibility of inbred mice to intracellular pathogens. Polymorphisms in the human Slc11a1/Nramp1 gene…
View article: Potential roles of micro<scp>RNA</scp>‐29a in the molecular pathophysiology of T‐cell acute lymphoblastic leukemia
Potential roles of micro<span>RNA</span>‐29a in the molecular pathophysiology of T‐cell acute lymphoblastic leukemia Open
Recent evidence has shown that deregulated expression of members of the micro RNA ‐29 (miR‐29) family may play a critical role in human cancer, including hematological malignancies. However, the roles of miR‐29 in the molecular pathophysio…
View article: Assessment of MLL methyltransferase gene expression in larynx carcinoma
Assessment of MLL methyltransferase gene expression in larynx carcinoma Open
Larynx cancer is the second most common type of cancer among all head and neck cancers. Deregulation of epigenetic effectors, including altered expression of histone methyltransferases from the MLL (mixed lineage leukemia) family, have bee…