María Ximena Rojas
YOU?
Author Swipe
View article: Over 1000 terms have been used to describe evidence synthesis: a scoping review
Over 1000 terms have been used to describe evidence synthesis: a scoping review Open
Objective To inform the development of an evidence synthesis taxonomy, we aimed to identify and examine all classification systems, typologies or taxonomies that have been proposed for evidence synthesis methods. Design Scoping review. Met…
View article: Effectiveness of Non-Pharmacological Interventions for Sleep Disorders in Enhancing Quality of Life, Cognitive Function, and Sleep Quality in Older Adults with Mild Cognitive Impairment: A Systematic Review and Meta-Analysis
Effectiveness of Non-Pharmacological Interventions for Sleep Disorders in Enhancing Quality of Life, Cognitive Function, and Sleep Quality in Older Adults with Mild Cognitive Impairment: A Systematic Review and Meta-Analysis Open
Background and Objectives: This systematic review with meta-analysis aimed to evaluate and synthesize the scientific evidence of interventions for sleep disorders on sleep quality, cognitive function, and quality of life in older adults wi…
View article: Genicular artery embolization for knee osteoarthritis: a systematic review with meta-analysis and cost-analysis
Genicular artery embolization for knee osteoarthritis: a systematic review with meta-analysis and cost-analysis Open
In summary, based on moderate to low-certainty evidence, it remains inconclusive whether there is any difference between GAE and standard treatment for KO. However, the use of GAE would increase the costs. Larger randomized controlled tria…
View article: Factors associated with asthma symptoms in Colombian subpopulations aged 1 to 17 and 18 to 59: Secondary analysis of the study “Prevalence of asthma and other allergic diseases in Colombia 2009–2010”
Factors associated with asthma symptoms in Colombian subpopulations aged 1 to 17 and 18 to 59: Secondary analysis of the study “Prevalence of asthma and other allergic diseases in Colombia 2009–2010” Open
Background: Asthma, a chronic inflammatory lung disease, is one of the leading causes of disability, demands on health resources, and poor quality of life. It is necessary to identify asthma-related risk factors to reduce the presence and …
View article: PD51 Effectiveness And Safety Of Vitamin D For COVID-19: A Living Evidence Synthesis Informing A Health Technology Assessment Report
PD51 Effectiveness And Safety Of Vitamin D For COVID-19: A Living Evidence Synthesis Informing A Health Technology Assessment Report Open
Introduction An evidence synthesis developed to inform decision-making on the use of vitamin D for preventing and treating COVID-19 showed that current available evidence is of low to very low quality. We set up a rigorous living evidence …
View article: OP25 Rapid Molecular Tests For Detecting Multidrug-Resistant Microorganisms: An Overview Of Systematic Reviews Within A Living Evidence Project
OP25 Rapid Molecular Tests For Detecting Multidrug-Resistant Microorganisms: An Overview Of Systematic Reviews Within A Living Evidence Project Open
Introduction Ranked among the top 10 global health threats, antimicrobial resistance (AMR) prompts concern. Embracing a living evidence synthesis (LES), we address this concern by informing health decision-makers about molecular tests for …
View article: PP107 Effectiveness And Safety Of Cytoreductive Surgery And Heated Intraperitoneal Chemotherapy For Pediatric Peritoneal Carcinomatosis: A Living Evidence Synthesis
PP107 Effectiveness And Safety Of Cytoreductive Surgery And Heated Intraperitoneal Chemotherapy For Pediatric Peritoneal Carcinomatosis: A Living Evidence Synthesis Open
Introduction The evidence synthesis developed to inform decision-making on the use of cytoreductive surgery (CRS) and heated intraperitoneal chemotherapy (HIPEC) for pediatric peritoneal carcinomatosis showed that currently available evide…
View article: Efficacy and safety of chimeric antigen receptor T-cell (CAR-T) therapy in hematologic malignancies: a living systematic review (protocol)
Efficacy and safety of chimeric antigen receptor T-cell (CAR-T) therapy in hematologic malignancies: a living systematic review (protocol) Open
Objective To determine the efficacy and safety of CAR-T therapy in the treatment of patients with hematologic malignancies, in comparison with other current therapies. Design A living systematic review Methods We will include randomized tr…
View article: TRENDS IN MORTALITY OF POTENTIAL PNEUMOCOCCAL PNEUMONIA IN COLOMBIA, 2006-2019
TRENDS IN MORTALITY OF POTENTIAL PNEUMOCOCCAL PNEUMONIA IN COLOMBIA, 2006-2019 Open
Intro: In 2010, PCV10 was introduced in the Colombian National Immunization Program (NIP) for children, with good vaccination coverage >82% since 2012. However, the NIP does not include routine pneumococcal vaccination for older adults. We…
View article: Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants
Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants Open
Given the low to moderate certainty of evidence for the effects of probiotic supplements on the risk of NEC and associated morbidity and mortality for very preterm or VLBW infants, and particularly for extremely preterm or ELBW infants, th…
View article: Efficacy and safety of chimeric antigen receptor T-cell (CAR-T) therapy in hematologic malignancies: a living systematic review on comparative studies
Efficacy and safety of chimeric antigen receptor T-cell (CAR-T) therapy in hematologic malignancies: a living systematic review on comparative studies Open
Background: Chimeric antigen receptor T-cell (CAR-T) cell therapies have been claimed to be curative in responsive patients. Nonetheless, response rates can vary according to different characteristics, and these therapies are associated wi…
View article: Cost-utility analysis of genomic profiling in early breast cancer in Colombia
Cost-utility analysis of genomic profiling in early breast cancer in Colombia Open
Background: In Colombia, the best strategy to establish indication for adjuvant chemotherapy in early breast cancer (EBC) remains unknown. This study aimed to identify the cost-utility of Oncotype DX™ (ODX) or Mammaprint™ (MMP) tests to es…
View article: Implementing living evidence to inform health decisions: A strategy for building capacity in health sector (Protocol)
Implementing living evidence to inform health decisions: A strategy for building capacity in health sector (Protocol) Open
Every day important healthcare decisions are made with incomplete or outdated information about the effects of the healthcare interventions available, what delivers the best value for the health system and where more research is needed. It…
View article: Fecal microbiota transplantation for treatment of moderate to severe ulcerative colitis: a living systematic review protocol
Fecal microbiota transplantation for treatment of moderate to severe ulcerative colitis: a living systematic review protocol Open
Background: Primary studies and systematic reviews assessing the safety and effectiveness of fecal microbiota transplantation as a treatment for ulcerative colitis are being continuously published. The objective of this review is to synthe…
View article: Which actionable statements qualify as good practice statements In Covid-19 guidelines? A systematic appraisal
Which actionable statements qualify as good practice statements In Covid-19 guidelines? A systematic appraisal Open
Objectives To evaluate the development and quality of actionable statements that qualify as good practice statements (GPS) reported in COVID-19 guidelines. Design and setting Systematic review . We searched MEDLINE, MedSci, China National …
View article: Good or best practice statements: proposal for the operationalisation and implementation of GRADE guidance
Good or best practice statements: proposal for the operationalisation and implementation of GRADE guidance Open
An evidence-based approach is considered the gold standard for health decision-making. Sometimes, a guideline panel might judge the certainty that the desirable effects of an intervention clearly outweigh its undesirable effects as high, b…
View article: Methodological approaches for developing and reporting living evidence synthesis: a study protocol
Methodological approaches for developing and reporting living evidence synthesis: a study protocol Open
Background: Living evidence (LE) refers to the methodological processes that permit new research findings to be continually incorporated into evidence synthesis. This approach is of great value in the resolution of relevant and rapidly cha…
View article: Efficacy and safety of chimeric antigen receptor T-cell (CAR-T) therapy in hematologic malignancies: a living systematic review (protocol)
Efficacy and safety of chimeric antigen receptor T-cell (CAR-T) therapy in hematologic malignancies: a living systematic review (protocol) Open
Objective: To determine the efficacy and safety of CAR-T therapy in the treatment of patients with hematologic malignancies, in comparison with other current therapies. Design: A living systematic review. Methods: We will include randomiz…
View article: Fecal microbiota transplantation for treatment of moderate to severe ulcerative colitis: a living systematic review protocol
Fecal microbiota transplantation for treatment of moderate to severe ulcerative colitis: a living systematic review protocol Open
Background: Several primary studies and systematic reviews (SRs) have been published over the past 10 years to assess the safety and effectiveness of fecal microbiota transplantation (FMT) as a treatment for ulcerative colitis. The objecti…
View article: Implementing living evidence to inform health decisions: A strategy for building capacity in health sector (Protocol)
Implementing living evidence to inform health decisions: A strategy for building capacity in health sector (Protocol) Open
Every day important healthcare decisions are made with incomplete or outdated information about the effects of the different health care interventions available, what delivers the best value for the health system and where more research is…
View article: Methods for living evidence synthesis: a systematic review protocol
Methods for living evidence synthesis: a systematic review protocol Open
Background: Living evidence (LE) refers to the methodological process that permits new research findings to be continually incorporated to evidence synthesis as they become available. This approach is of great value in the resolution of re…
View article: Cost-Effectiveness Analysis of Genomic Profiling in Early Breast Cancer in Colombia
Cost-Effectiveness Analysis of Genomic Profiling in Early Breast Cancer in Colombia Open
Background: In Colombia, the best strategy to establish indication for adjuvant chemotherapy in early breast cancer (EBC) remains unknown. This study aimed to identify the cost-effectiveness of various strategies to establish the necessity…
View article: Cost-effectiveness analysis of genomic profiling in early breast cancer in Colombia
Cost-effectiveness analysis of genomic profiling in early breast cancer in Colombia Open
BackgroundThe best strategy to establish indication for adjuvant chemotherapy in early breast cancer (EBC) in Colombia is unknown. This study aimed to identify the cost-effectiveness of various strategies to establish the necessity of adju…
View article: Macrolides for the treatment of COVID-19: a living, systematic review
Macrolides for the treatment of COVID-19: a living, systematic review Open
Objective This living, systematic review aims to provide a timely, rigorous, and continuously updated summary of the evidence available on the role of macrolides for treating patients with COVID-19. Design A living, systematic review. Data…