Mariah Eisner
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View article: Variability of esophageal food impaction management across pediatric specialties
Variability of esophageal food impaction management across pediatric specialties Open
Esophageal food impaction (EFI) requires urgent endoscopy, typically performed by pediatric gastroenterologists (GI) or pediatric surgeons. We investigated differences in the approach between GI and surgeons to EFIs at a single pediatric c…
The Impact of Social Determinants of Health on Quality of Life in a Cohort of 1300 Children With Epilepsy Open
In children with epilepsy, SDOH were associated with HRQoL, but to a lesser degree than epilepsy-related factors. Higher seizure burden, frequent ASM side effects, and developmental/learning issues had the largest association with lower HR…
A New Simple to Use Chest CT Scoring System: Validation Study Open
Background Current chest computed tomography (CT) based scoring systems are complex. Objective Validity of new simple and easy to use chest CT scoring system was determined in pwCF with varying severity of lung disease. Study Design Three …
View article: Status Epilepticus Protocol Variation Across Accredited National Association of Epilepsy Centers Members
Status Epilepticus Protocol Variation Across Accredited National Association of Epilepsy Centers Members Open
Despite the importance of timeliness in SE management, one third of institutional protocols did not specify treatment times. This analysis of US hospital inpatient SE protocols provides expert opinion regarding infusion therapy management …
1038 Prevalence of Restless Leg Syndrome in Children with Cystic Fibrosis Open
Introduction Restless leg syndrome (RLS) is a sleep disorder affecting 2-4% of school-aged children and adolescents with iron deficiency being implicated in its pathogenesis. Patients with cystic fibrosis (CF) are at risk for iron deficien…
Real-life impact of genotype and severity of lung disease on efficacy of elexacaftor-tezacaftor-ivacaftor in people with cystic fibrosis Open
ETI therapy improved clinical outcomes in pwCF which were impacted by severity of underlying lung disease.
Incorporating Aeroallergen Exposure Metrics into Clinical Asthma Care: A Pilot Study Using A Mixed-Methods Survey to Assess Aeroallergen Knowledge, Perceived Asthma Control, and Mitigation Strategies in Households of Children with Asthma Open
Objective: Mitigation of household allergens is associated with the reduction of asthma exacerbations in those with allergic asthma and is recommended in recent asthma guidelines. However, we need to better understand patient knowledge of …
Edinburgh postnatal depression scale score elevation in caregivers of infants with cystic fibrosis Open
Introduction The diagnosis of cystic fibrosis (CF) can impact the mental health of caregivers. This study aimed to explore prevalence of postpartum depression (PPD) symptoms in caregivers of infants with CF or CFTR‐related metabolic syndro…
View article: Diffuse alveolar hemorrhage in pediatrics: Etiologies and outcomes
Diffuse alveolar hemorrhage in pediatrics: Etiologies and outcomes Open
Background Many conditions, including autoimmune disease and idiopathic pulmonary hemosiderosis (IPH), can cause diffuse alveolar hemorrhage (DAH). Little is known about the epidemiology and outcomes in children. Objectives This retrospect…
Innate immune responses are increased in children with acute asthma exacerbation Open
Background Little is known about the immune responses during acute asthma exacerbation. In this study, we examined immune responses in children following an acute asthma exacerbation. Methods We evaluated pro‐inflammatory cytokine levels a…
View article: Age‐specific predictors of disease severity in children with respiratory syncytial virus infection beyond infancy and through the first 5 years of age
Age‐specific predictors of disease severity in children with respiratory syncytial virus infection beyond infancy and through the first 5 years of age Open
Background Respiratory syncytial virus (RSV) infection is associated with significant morbidity in infants. Risk factors for severe disease beyond the first 2 years of life have not been fully defined. Methods Children 24–59 months) risk f…
Beyond Anatomy: Use of Sinus Propagation Mapping to Identify the Slow Pathway for Cryoablation in Pediatric Patients Open
Slow pathway modification via cryoablation is a common treatment of atrioventricular nodal re-entrant tachycardia (AVNRT) in pediatric patients. Sinus propagation mapping (SPM) is a tool that has been used to augment identification of the …
View article: 1624. SARS-CoV-2 Maternal Vaccination Induces More Efficient Placental Antibody Transfer to Newborns than SARS-CoV-2 Infection During Pregnancy
1624. SARS-CoV-2 Maternal Vaccination Induces More Efficient Placental Antibody Transfer to Newborns than SARS-CoV-2 Infection During Pregnancy Open
Background Passive immunization via maternal antibodies (Ab) is a key mechanism for infant protection in early life. This study analyzed the landscape of passive immunization induced by SARS-CoV-2 infection and/or vaccination by comparing …
Predictors of recurrent wheezing in late preterm infants Open
Introduction Premature infants have an increased risk of respiratory morbidity, including the development of recurrent wheezing. We sought to determine perinatal factors in late preterm infants associated with an increased risk of recurren…
Elexacaftor-Tezacaftor-Ivacaftor Therapy for Chronic Sinus Disease in Cystic Fibrosis Open
Importance Cystic fibrosis (CF) is a multiorgan genetic disease with progressive upper and lower airway involvement. The effects of CF transmembrane conductance regulator (CFTR) modifier therapies on CF-related upper airway disease, specif…
Impact of Elexacaftor–Tezacaftor–Ivacaftor on lung disease in cystic fibrosis Open
Background In people with cystic fibrosis (pwCF), the impact of cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapies, such as Elexacaftor–Tezacaftor–Ivacaftor (ETI), on structural changes in the lungs is unclear. …
Prevalence of Elevated Blood Pressure and Left Ventricular Hypertrophy in Adolescents with Congenital Heart Disease Open
Background Left ventricular hypertrophy (LVH) associated with hypertension (HTN) is a predictor of cardiovascular (CV) events in adulthood. LVH is defined using left ventricular mass indexed to height 2.7 (LVMI-ht 2.7 ) with current guidel…
Associations between testing and treatment pathways in lesional temporal or extratemporal epilepsy: A census survey of NAEC center directors Open
Objective The evaluation to determine candidacy and treatment for epilepsy surgery in persons with drug‐resistant epilepsy (DRE) is not uniform. Many non‐invasive and invasive tests are available to ascertain an appropriate treatment strat…