Marianne S Rose
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View article: Reply to Burt LA, et al.: Adverse Effects of High-Dose Vitamin D Supplementation on Volumetric Bone Density Are Greater in Females Than Males
Reply to Burt LA, et al.: Adverse Effects of High-Dose Vitamin D Supplementation on Volumetric Bone Density Are Greater in Females Than Males Open
We thank Dr Boucher(1) for her comments on our findings and hope our response provides further clarification. It is important to emphasize that our results are based on exploratory outcomes from our randomized controlled trial, and it is o…
View article: Reply to Vitamin D Supplements: Is Bone Loss by HR-pQCT Really Negative?
Reply to Vitamin D Supplements: Is Bone Loss by HR-pQCT Really Negative? Open
The author questions whether the dose-response effect of vitamin D supplementation we showed using HR-pQCT should be of concern to clinicians, particularly because those findings were not reflected in our DXA-based area BMD (aBMD) measures…
View article: Reply to Effects of High-Dose Vitamin D Supplementation on Bone Fragility
Reply to Effects of High-Dose Vitamin D Supplementation on Bone Fragility Open
We thank Dr Sugiyama for his response to our article. Dr Sugiyama raises the interesting possibility that high-dose vitamin D causes an increase in serum calcium (as found in our study), which, in turn, might mediate the decrease in volume…
View article: Adverse Effects of High-Dose Vitamin D Supplementation on Volumetric Bone Density Are Greater in Females than Males
Adverse Effects of High-Dose Vitamin D Supplementation on Volumetric Bone Density Are Greater in Females than Males Open
Three years of high-dose vitamin D supplementation (400 IU, 4000 IU, 10,000 IU) in healthy vitamin D–sufficient individuals aged 55 to 70 years (serum 25(OH)D 30–125 nmol/L at baseline), resulted in a negative dose-response relationship fo…
View article: Levothyroxine prescribing and laboratory test use after a minor change in reference range for thyroid-stimulating hormone
Levothyroxine prescribing and laboratory test use after a minor change in reference range for thyroid-stimulating hormone Open
Our findings suggest that clinicians may have responded to mildly elevated TSH results with new or increased levothyroxine prescriptions and more TSH testing. Knowledge translation efforts may be useful to accompany minor changes in refere…
View article: Effect of High-Dose Vitamin D Supplementation on Volumetric Bone Density and Bone Strength
Effect of High-Dose Vitamin D Supplementation on Volumetric Bone Density and Bone Strength Open
ClinicalTrials.gov Identifier: NCT01900860.
View article: Screening with Papanicolaou tests in Alberta: Are we Choosing Wisely?
Screening with Papanicolaou tests in Alberta: Are we Choosing Wisely? Open
Within the geographic regions of Alberta, provincial, national, and international guidelines for screening with Pap tests are inconsistently followed. This strongly echoes the need for clinicians and patients to consider the Choosing Wisel…
View article: Supportive Text Messages to Reduce Mood Symptoms and Problem Drinking in Patients With Primary Depression or Alcohol Use Disorder: Protocol for an Implementation Research Study
Supportive Text Messages to Reduce Mood Symptoms and Problem Drinking in Patients With Primary Depression or Alcohol Use Disorder: Protocol for an Implementation Research Study Open
ClinicalTrials.gov: NCT02327858; https://clinicaltrials.gov/ct2/show/NCT02327858 (Archived by WebCite at https://clinicaltrials.gov/ct2/show/NCT02327858).
View article: Effect of Atlas Vertebrae Realignment in Subjects with Migraine: An Observational Pilot Study
Effect of Atlas Vertebrae Realignment in Subjects with Migraine: An Observational Pilot Study Open
Introduction . In a migraine case study, headache symptoms significantly decreased with an accompanying increase in intracranial compliance index following atlas vertebrae realignment. This observational pilot study followed eleven neurolo…