Mariarosaria Valente
YOU?
Author Swipe
View article: Intravenous thrombolysis in patients with acute ischaemic stroke and active cancer (the ITACA-stroke study)
Intravenous thrombolysis in patients with acute ischaemic stroke and active cancer (the ITACA-stroke study) Open
View article: Botulinum toxin as an effective rescue treatment after failure of anti-CGRP monoclonal antibodies in chronic migraine patients
Botulinum toxin as an effective rescue treatment after failure of anti-CGRP monoclonal antibodies in chronic migraine patients Open
anti-CGRP monoclonal antibodies (anti-CGRP mAbs) represent a highly effective prophylactic treatment for chronic migraineurs, but for some subjects they are ineffective. We aimed to determine if OnabotulinumtoxinA (BoNT/A) treatment may be…
View article: Timing and Safety of Anticoagulation Reinitiation After Intracranial Hemorrhage in Patients With Mechanical Valves
Timing and Safety of Anticoagulation Reinitiation After Intracranial Hemorrhage in Patients With Mechanical Valves Open
In patients with MHVs who experienced an ICH, this meta-analysis found that resumption of AC was associated with a recurrent ICH rate of 11.4% and an ischemic stroke rate of 6.1% during AC suspension. Meta-regression suggested a lower risk…
View article: Mid‐Regional Proadrenomedullin in Cerebrospinal Fluid Is a Reliable Diagnostic and Prognostic Marker for Acute Meningoencephalitis and Neurological Disorders
Mid‐Regional Proadrenomedullin in Cerebrospinal Fluid Is a Reliable Diagnostic and Prognostic Marker for Acute Meningoencephalitis and Neurological Disorders Open
Objectives Despite numerous pieces of evidence of its important role as a diagnostic and prognostic biomarker in infectious diseases and sepsis, adrenomedullin (ADM) was only poorly investigated in cerebrospinal fluid (CSF) in central nerv…
View article: Low- vs. high-frequency deep brain stimulation in Parkinson's disease: A two-center double-blind crossover trial
Low- vs. high-frequency deep brain stimulation in Parkinson's disease: A two-center double-blind crossover trial Open
View article: Intraparenchymal cerebral hemorrhage in a patient undergoing treatment with galcanezumab: the importance of adequate blood pressure control
Intraparenchymal cerebral hemorrhage in a patient undergoing treatment with galcanezumab: the importance of adequate blood pressure control Open
Background: Calcitonin gene-related peptide (CGRP) is a neuropeptide involved in pain transmission and modulation, and implicated in migraine pathophysiology. Due to the vasodilatory action of CGRP, anti-CGRP drugs, while ameliorating migr…
View article: Intravenous Thrombolysis in Patients With Recent Intake of Direct Oral Anticoagulants: A Target Trial Analysis and Comparison With Reversal Agent Use
Intravenous Thrombolysis in Patients With Recent Intake of Direct Oral Anticoagulants: A Target Trial Analysis and Comparison With Reversal Agent Use Open
BACKGROUND: Intravenous thrombolysis (IVT) in patients with recent ingestion of direct oral anticoagulants (DOACs) is a frequent challenge and remains controversial. The benefit of DOAC reversal before IVT is uncertain. METHODS: Using targ…
View article: Intravenous thrombolysis in the context of stroke and cancer
Intravenous thrombolysis in the context of stroke and cancer Open
View article: The Role of <scp>Electroencephalography</scp> in Predicting Post‐Stroke Seizures and an Updated Prognostic Model ( <scp>SeLECT</scp> ‐ <scp>EEG</scp> )
The Role of <span>Electroencephalography</span> in Predicting Post‐Stroke Seizures and an Updated Prognostic Model ( <span>SeLECT</span> ‐ <span>EEG</span> ) Open
Objective Seizures negatively impact stroke outcomes, highlighting the need for reliable predictors of post‐stroke epilepsy. Although acute symptomatic seizures are a known risk factor, most stroke survivors who develop epilepsy do not exp…
View article: The impact of inflammatory markers on clinical outcomes in acute ischemic stroke patients following mechanical thrombectomy: A multicentre study
The impact of inflammatory markers on clinical outcomes in acute ischemic stroke patients following mechanical thrombectomy: A multicentre study Open
View article: Identifying EEG biomarkers of sense of embodiment in virtual reality: insights from spatio-spectral features
Identifying EEG biomarkers of sense of embodiment in virtual reality: insights from spatio-spectral features Open
The Sense of Embodiment (SoE) refers to the subjective experience of perceiving a non-biological body part as one's own. Virtual Reality (VR) provides a powerful platform to manipulate SoE, making it a crucial factor in immersive human-com…
View article: Age‐Specific Differences in Inflammatory Biomarkers and Their Impact on Futile Recanalization After Mechanical Thrombectomy: An Inverse Probability Weighting Analysis
Age‐Specific Differences in Inflammatory Biomarkers and Their Impact on Futile Recanalization After Mechanical Thrombectomy: An Inverse Probability Weighting Analysis Open
Background Mechanical thrombectomy (MT) is the standard treatment for large vessel occlusion (LVO) stroke. However, a substantial proportion of patients experience poor functional outcomes despite successful reperfusion, namely futile reca…
View article: Intraoperative Seizures in Glioma Surgery: Is It Really Only an Intraoperative Issue?
Intraoperative Seizures in Glioma Surgery: Is It Really Only an Intraoperative Issue? Open
Intraoperative seizures (IOS) represent a complication during surgery of diffuse low-grade gliomas (DLGGs), particularly in cases of awake craniotomy, history of tumor-related epilepsy (TRE), and cortical mapping [...]
View article: Association of the Timing and Type of Acute Symptomatic Seizures With Poststroke Epilepsy and Mortality
Association of the Timing and Type of Acute Symptomatic Seizures With Poststroke Epilepsy and Mortality Open
BACKGROUND: Acute symptomatic seizures (ASyS) increase the risk of epilepsy and mortality after a stroke. The impact of the timing and type of ASyS remains unclear. METHODS: This multicenter cohort study included data from 9 centers betwee…
View article: The effects of transcranial magnetic stimulation in motor symptoms of Parkinson’s disease: an overview of systematic reviews with meta-analysis
The effects of transcranial magnetic stimulation in motor symptoms of Parkinson’s disease: an overview of systematic reviews with meta-analysis Open
View article: C-reactive protein elevation and subsequent atrial fibrillation detection after ischemic stroke treated with mechanical thrombectomy: An inverse probability weighting analysis
C-reactive protein elevation and subsequent atrial fibrillation detection after ischemic stroke treated with mechanical thrombectomy: An inverse probability weighting analysis Open
Background and aims: Mechanical thrombectomy (MT) is an effective treatment for acute ischemic stroke due to large vessel occlusion (LVO). Atrial fibrillation (AF) can be known before the stroke (or prevalent AF) or be newly detected after…
View article: Transplante de pâncreas isolado versus transplante simultâneo pâncreas-rim em diabéticos tipo 1: Quem realmente se beneficia? Uma meta-análise
Transplante de pâncreas isolado versus transplante simultâneo pâncreas-rim em diabéticos tipo 1: Quem realmente se beneficia? Uma meta-análise Open
Pacientes com diabetes tipo 1 em estágio avançado de doença renal crônica podem ser tratados com transplante de pâncreas isolado (PTA) ou com transplante simultâneo pâncreas-rim (SPK). A escolha da modalidade ideal continua controversa. Es…
View article: Stress hyperglycemia indexes and early neurological deterioration in spontaneous intracerebral hemorrhage
Stress hyperglycemia indexes and early neurological deterioration in spontaneous intracerebral hemorrhage Open
Aim To evaluate the relationship of early neurological deterioration (END) with admission glycemia (aG) and new stress hyperglycemia indexes in spontaneous intracerebral hemorrhage (ICH) patients. Methods The present retrospective study in…
View article: Impact of atrial fibrillation on outcomes in stroke patients with tandem occlusions treated with thrombectomy: A multicentre study
Impact of atrial fibrillation on outcomes in stroke patients with tandem occlusions treated with thrombectomy: A multicentre study Open
Background: Tandem occlusions, involving simultaneous extracranial and intracranial artery blockages, represent a complex subtype of acute ischemic stroke treated with mechanical thrombectomy (MT). However, to date, the impact of atrial fi…
View article: Prediction, prevention, and precision treatment of immune checkpoint inhibitor neurological toxicity using autoantibodies, cytokines, and microbiota
Prediction, prevention, and precision treatment of immune checkpoint inhibitor neurological toxicity using autoantibodies, cytokines, and microbiota Open
Cancer immunotherapy with immune checkpoint inhibitors (ICIs) has revolutionized oncology, significantly improving survival across multiple cancer types. ICIs, such as anti-PD-1 (e.g. nivolumab, pembrolizumab), anti-PD-L1 (e.g. atezolizuma…
View article: Prognostic Impact of Malnutrition Evaluated via Bioelectrical Impedance Vector Analysis (BIVA) in Acute Ischemic Stroke: Findings from an Inverse Probability Weighting Analysis
Prognostic Impact of Malnutrition Evaluated via Bioelectrical Impedance Vector Analysis (BIVA) in Acute Ischemic Stroke: Findings from an Inverse Probability Weighting Analysis Open
Background. The association between malnutrition and poor outcomes in stroke patients has, to date, been evaluated using composite scores derived from laboratory measurements. However, Bioelectrical Impedance Analysis (BIA) and its advance…
View article: Predictors of futile recanalization after intravenous thrombolysis in stroke patients transferred for endovascular treatment
Predictors of futile recanalization after intravenous thrombolysis in stroke patients transferred for endovascular treatment Open
Some patients with large vessel occlusion (LVO) achieve insufficient clinical improvement (futile recanalization, FR) after intravenous thrombolysis (IVT) during inter-hospital transfer for thrombectomy, while others show good outcomes (ef…
View article: Outcomes of Mechanical Thrombectomy in Patients With Ischemic Stroke and Heart Failure. A Systematic Review and Meta‐analysis
Outcomes of Mechanical Thrombectomy in Patients With Ischemic Stroke and Heart Failure. A Systematic Review and Meta‐analysis Open
Background Patients with heart failure (HF) treated with mechanical thrombectomy (MT) for acute ischemic stroke were underrepresented in clinical trials on MT. Our systematic review and meta‐analysis aim to assess differences in outcomes b…
View article: Effectiveness and tolerability of rimegepant in the acute treatment of migraine: a real-world, prospective, multicentric study (GAINER study)
Effectiveness and tolerability of rimegepant in the acute treatment of migraine: a real-world, prospective, multicentric study (GAINER study) Open
The study was preregistered on clinicaltrial.gov, NCT05903027.
View article: Sex-based differences in inflammatory predictors of outcomes in patients undergoing mechanical thrombectomy: an inverse probability weighting analysis
Sex-based differences in inflammatory predictors of outcomes in patients undergoing mechanical thrombectomy: an inverse probability weighting analysis Open
Background: Inflammatory biomarkers, key predictors of ischemic stroke prognosis, may exhibit sex-specific predictive patterns. Objectives: This study investigates sex-based differences in inflammatory biomarkers as predictors of 90-day cl…
View article: A Case of Multiple System Atrophy Associated with a Homozygous Coq2 Mutation (N228s, C.683a>G)
A Case of Multiple System Atrophy Associated with a Homozygous Coq2 Mutation (N228s, C.683a>G) Open
View article: Impact of Sex on Clinical Outcomes of Tandem Occlusion in Acute Ischemic Stroke Patients Treated With Mechanical Thrombectomy. A Propensity‐Matched Analysis
Impact of Sex on Clinical Outcomes of Tandem Occlusion in Acute Ischemic Stroke Patients Treated With Mechanical Thrombectomy. A Propensity‐Matched Analysis Open
Background Although mechanical thrombectomy (MT) represents the standard of care for ischemic stroke due to large‐vessel occlusion (LVO), the impact of sex on outcomes in tandem occlusions remains unclear. We investigated sex‐based differe…
View article: Association of the timing and type of acute symptomatic seizures with post-stroke epilepsy and mortality
Association of the timing and type of acute symptomatic seizures with post-stroke epilepsy and mortality Open
Background Acute symptomatic seizures (ASyS) increase the risk of epilepsy and mortality after a stroke. The impact of the timing and type of ASyS remains unclear. Methods This multicenter cohort study included data from nine centers betwe…
View article: Botulinum Toxin Type A for Trigeminal Neuralgia: A Comprehensive Literature Review
Botulinum Toxin Type A for Trigeminal Neuralgia: A Comprehensive Literature Review Open
Trigeminal neuralgia is a neuropathic pain syndrome responsive to botulinum toxin type A therapy. This review had the goal of analyzing the different studies published from 2002 to January 2024 to better define the techniques and the types…
View article: Outcomes of different anesthesia techniques in nonagenarians treated with mechanical thrombectomy for anterior circulation large vessel occlusion: An inverse probability weighting analysis
Outcomes of different anesthesia techniques in nonagenarians treated with mechanical thrombectomy for anterior circulation large vessel occlusion: An inverse probability weighting analysis Open
Introduction: There is a lack of evidence for the optimal type of anesthesia technique in patients ⩾ 90 years with acute ischemic stroke undergoing mechanical thrombectomy (MT) as this subgroup of patients was often excluded or under-repre…