Maricarmen Chacín
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View article: Laser-Assisted Lipolysis: A Promising Alternative to Traditional Liposuction
Laser-Assisted Lipolysis: A Promising Alternative to Traditional Liposuction Open
Background Laser-Assisted Lipolysis (LAL) has emerged as a modern advancement in body contouring, offering solutions to limitations of traditional liposuction such as prolonged recovery, increased bruising, and limited skin-tightening effe…
View article: Role of Polyphenols in Dermatological Diseases: Exploring Pharmacotherapeutic Mechanisms and Clinical Implications
Role of Polyphenols in Dermatological Diseases: Exploring Pharmacotherapeutic Mechanisms and Clinical Implications Open
Although not frequently lethal, dermatological diseases represent a common cause of consultation worldwide. Due to the natural and non-invasive approach of phytotherapy, research for novel alternatives, such as polyphenols, to treat skin d…
View article: Dietary Polyphenols and Gut Microbiota Cross-Talk: Molecular and Therapeutic Perspectives for Cardiometabolic Disease: A Narrative Review
Dietary Polyphenols and Gut Microbiota Cross-Talk: Molecular and Therapeutic Perspectives for Cardiometabolic Disease: A Narrative Review Open
The intricate interplay between the gut microbiota and polyphenols has emerged as a captivating frontier in understanding and potentially harnessing the therapeutic potential of these bioactive compounds. Phenolic compounds, renowned for t…
View article: Successfully Nonsurgical Epidermoid Cyst Management with Recombinant Hydrolytic Enzymes: A Case Report
Successfully Nonsurgical Epidermoid Cyst Management with Recombinant Hydrolytic Enzymes: A Case Report Open
Intralesional administration of hydrolytic enzymes represents an innovative technique in the management of E.C.s. However, further controlled studies are required to determine the efficacy and safety of this procedure.
View article: A novel hybrid BonT‐A and hyaluronic acid cannula‐based technique for eyelid ptosis and periorbital rejuvenation
A novel hybrid BonT‐A and hyaluronic acid cannula‐based technique for eyelid ptosis and periorbital rejuvenation Open
Background Eyelid ptosis is characterized by an inferior displacement of the upper eyelid when the eye assumes its primary position. Besides its aesthetic implications, ptosis can also adversely affect visual acuity. Objective This study a…
View article: Epidemiological behavior of childhood obesity: A continental point of view
Epidemiological behavior of childhood obesity: A continental point of view Open
Weight excess during the childhood has been one of the most critical public health problems worldwide in the past few decades. It is considered a significant predictor of adulthood obesity, increased cardiometabolic diseases, and premature…
View article: Antioxidants in Photoaging: From Molecular Insights to Clinical Applications
Antioxidants in Photoaging: From Molecular Insights to Clinical Applications Open
Photoaging (PA) is considered a silent disease affecting millions of people globally and is defined as skin damage due to prolonged exposure to ultraviolet radiation (UVR) from the sun. Physiologically, the skin is in a state of renewal an…
View article: Weight Regain after Metabolic Surgery: Beyond the Surgical Failure
Weight Regain after Metabolic Surgery: Beyond the Surgical Failure Open
Patients undergoing metabolic surgery have factors ranging from anatomo-surgical, endocrine metabolic, eating patterns and physical activity, mental health and psychological factors. Some of the latter can explain the possible pathophysiol…
View article: The Role of Specialized Pro-Resolving Lipid Mediators in Inflammation-Induced Carcinogenesis
The Role of Specialized Pro-Resolving Lipid Mediators in Inflammation-Induced Carcinogenesis Open
Cancer is a process involving cell mutation, increased proliferation, invasion, and metastasis. Over the years, this condition has represented one of the most concerning health problems worldwide due to its significant morbidity and mortal…
View article: Intrinsic and environmental basis of aging: A narrative review
Intrinsic and environmental basis of aging: A narrative review Open
Longevity has been a topic of interest since the beginnings of humanity, yet its aetiology and precise mechanisms remain to be elucidated. Aging is currently viewed as a physiological phenomenon characterized by the gradual degeneration of…
View article: Low Doses of Melatonin to Improve Sleep in Children with ADHD: An Open-Label Trial
Low Doses of Melatonin to Improve Sleep in Children with ADHD: An Open-Label Trial Open
Objective. Only a few studies assessing the sleep effects of low doses of melatonin (aMT) have been performed in the past, most of them in adults, and only one in subjects with attention-deficit/hyperactivity disorder (ADHD). The aim of th…
View article: Exploring the Relationship between the Gut Microbiota and Ageing: A Possible Age Modulator
Exploring the Relationship between the Gut Microbiota and Ageing: A Possible Age Modulator Open
The gut microbiota (GM) has been the subject of intense research in recent years. Therefore, numerous factors affecting its composition have been thoroughly examined, and with them, their function and role in the individual’s systems. The …
View article: A case report: Staphylococcal scalded skin syndrome in a minor infant
A case report: Staphylococcal scalded skin syndrome in a minor infant Open
Staphylococcal scald skin syndrome is an entity first described by Ritter Von Rittershain in 1878, which was called neonatal exfoliative dermatitis. This situation belongs to a group of pathologies caused by toxins produced by Staphylococc…
View article: Role of Gut Microbiome in Atherosclerosis: Molecular and TherapeuticAspects
Role of Gut Microbiome in Atherosclerosis: Molecular and TherapeuticAspects Open
Atherosclerosis is one of the most relevant and prevalent cardiovascular diseases of our time. It is one of the pathological entities that increases the morbidity and mortality index in the adult population. Pathophysiological connections …
View article: Hypertension, emotions and happiness: A brief view from the biology to the positive psychology
Hypertension, emotions and happiness: A brief view from the biology to the positive psychology Open
High blood pressure (HBP) is a silent disease with an extremely high prevalence worldwide. It is considered the leading risk factor for cardiovascular (CVD) and neurovascular disorders. The etiology of hypertension is based on various gene…
View article: Metabolic Reprogramming in Cancer Cells: Emerging Molecular Mechanisms and Novel Therapeutic Approaches
Metabolic Reprogramming in Cancer Cells: Emerging Molecular Mechanisms and Novel Therapeutic Approaches Open
The constant changes in cancer cell bioenergetics are widely known as metabolic reprogramming. Reprogramming is a process mediated by multiple factors, including oncogenes, growth factors, hypoxia-induced factors, and the loss of suppresso…
View article: Specialized Proresolving Lipid Mediators: A Potential Therapeutic Target for Atherosclerosis
Specialized Proresolving Lipid Mediators: A Potential Therapeutic Target for Atherosclerosis Open
Cardiovascular disease (CVD) is a global public health issue due to its high morbidity, mortality, and economic impact. The implementation of innovative therapeutic alternatives for CVD is urgently required. Specialized proresolving lipid …
View article: COVID-19 en niños y adolescentes: Mirando un poco más allá de lo físico
COVID-19 en niños y adolescentes: Mirando un poco más allá de lo físico Open
La pandemia de COVID-19 ha sido un acontecimiento mundial sin precedentes históricos cercanos. El distanciamiento físico y otras restricciones impuestas por los gobiernos en todo el mundo para contener la propagación del virus han …
View article: The Sick Adipose Tissue: New Insights Into Defective Signaling and Crosstalk With the Myocardium
The Sick Adipose Tissue: New Insights Into Defective Signaling and Crosstalk With the Myocardium Open
Adipose tissue (AT) biology is linked to cardiovascular health since obesity is associated with cardiovascular disease (CVD) and positively correlated with excessive visceral fat accumulation. AT signaling to myocardial cells through solub…
View article: The Role of the α Cell in the Pathogenesis of Diabetes: A World beyond the Mirror
The Role of the α Cell in the Pathogenesis of Diabetes: A World beyond the Mirror Open
Type 2 Diabetes Mellitus (T2DM) is one of the most prevalent chronic metabolic disorders, and insulin has been placed at the epicentre of its pathophysiological basis. However, the involvement of impaired alpha (α) cell function has been r…
View article: Advanced Glycation End Products: New Clinical and Molecular Perspectives
Advanced Glycation End Products: New Clinical and Molecular Perspectives Open
Diabetes mellitus (DM) is considered one of the most massive epidemics of the twenty-first century due to its high mortality rates caused mainly due to its complications; therefore, the early identification of such complications becomes a …
View article: Metabolic Syndrome: Is It Time to Add the Central Nervous System?
Metabolic Syndrome: Is It Time to Add the Central Nervous System? Open
Metabolic syndrome (MS) is a set of cardio-metabolic risk factors that includes central obesity, hyperglycemia, hypertension, and dyslipidemias. The syndrome affects 25% of adults worldwide. The definition of MS has evolved over the last 8…
View article: BACTERIAL TRANSLOCATION: MICROBIOTA-INTESTINE-LUNG AXIS AND PRO-INFLAMMATORY STATUS IN THE SEVERITY OF COVID-19
BACTERIAL TRANSLOCATION: MICROBIOTA-INTESTINE-LUNG AXIS AND PRO-INFLAMMATORY STATUS IN THE SEVERITY OF COVID-19 Open
Although severe acute respiratory syndrome coronavirus – 2 (SARS-CoV-2), causing coronavirus disease 2019 (COVID-19) pandemic, is primarily associated with a respiratory infection, it has also been linked to multisystem involvement that in…
View article: Lipid Accumulation Product Is More Related to Insulin Resistance than the Visceral Adiposity Index in the Maracaibo City Population, Venezuela
Lipid Accumulation Product Is More Related to Insulin Resistance than the Visceral Adiposity Index in the Maracaibo City Population, Venezuela Open
Background. Visceral adiposity is related to insulin resistance (IR), a metabolic state considered as a risk factor for other cardiometabolic diseases. In that matter, mathematical indexes such as the visceral adiposity index (VAI) and the…
View article: Role of Endocrine-Disrupting Chemicals in the Pathogenesis of Non-Alcoholic Fatty Liver Disease: A Comprehensive Review
Role of Endocrine-Disrupting Chemicals in the Pathogenesis of Non-Alcoholic Fatty Liver Disease: A Comprehensive Review Open
Non-alcoholic fatty liver disease (NAFLD) is considered the most common liver disorder, affecting around 25% of the population worldwide. It is a complex disease spectrum, closely linked with other conditions such as obesity, insulin resis…
View article: Prevalencia de sobrepeso y obesidad en escolares de San José de Cúcuta, Norte de Santander, Colombia
Prevalencia de sobrepeso y obesidad en escolares de San José de Cúcuta, Norte de Santander, Colombia Open
Introducción y Objetivo: El sobrepeso y la obesidad infantil son problemas de salud emergentes en países con un estilo de vida occidental tanto en la niñez como en edad adulta. Debido a la escasa información sobre este tem…
View article: Age-specific waist circumference cutoff-points for abdominal obesity diagnosis: a personalized strategy for a large Venezuelan population
Age-specific waist circumference cutoff-points for abdominal obesity diagnosis: a personalized strategy for a large Venezuelan population Open
View article: Cultura de paz en la pandemia por SARS-COV-2: confinamiento, tics y las redes sociales
Cultura de paz en la pandemia por SARS-COV-2: confinamiento, tics y las redes sociales Open
Súbitamente nuestro planeta ha quedado atrapado en una pandemia que todo el mundo esperaba pero para la cual casi nadie estaba preparado. Esto ha desencadenado una crisis mundial sin precedentes y ha dejado casi 25 millones de casos y un m…
View article: Microbiota and Diabetes Mellitus: Role of Lipid Mediators
Microbiota and Diabetes Mellitus: Role of Lipid Mediators Open
Diabetes Mellitus (DM) is an inflammatory clinical entity with different mechanisms involved in its physiopathology. Among these, the dysfunction of the gut microbiota stands out. Currently, it is understood that lipid products derived fro…
View article: Análisis clínico-epidemiológico de las subfracciones HDL2 y HDL3 en adultos de la ciudad de Maracaibo, Venezuela
Análisis clínico-epidemiológico de las subfracciones HDL2 y HDL3 en adultos de la ciudad de Maracaibo, Venezuela Open
Objetivo: Realizar un análisis clínico-epidemiológico de las subfracciones de colesterol unido a lipoproteinas de alta densidad (HDL-C, por sus siglas en inglés) en adultos de la ciudad de Maracaibo, Venezuela. Materiales y métodos: Se rea…