Marie Demonceaux
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View article: Crystal structure of the sucrose phosphorylase from <i>Alteromonas mediterranea</i> shows a loop transition in the active site
Crystal structure of the sucrose phosphorylase from <i>Alteromonas mediterranea</i> shows a loop transition in the active site Open
Sucrose phosphorylases are essential enzymes regulating sucrose metabolism, and it has been shown that a loop rearrangement is essential to their catalytic cycle. Crystal structures of only six sucrose phosphorylase enzymes are available. …
View article: Pharmacokinetic Prediction and Cytotoxicity of New Quercetin Derivatives
Pharmacokinetic Prediction and Cytotoxicity of New Quercetin Derivatives Open
Quercetin (QUE) possesses various pharmacological properties; however, its low bioavailability and solubility hinder its beneficial effects. Enzymatic glycosylation has been explored to improve these aspects. In the present study, we used …
View article: Sucrose phosphorylase from Alteromonas mediterranea: Structural insight into the regioselective α-glucosylation of (+)-catechin
Sucrose phosphorylase from Alteromonas mediterranea: Structural insight into the regioselective α-glucosylation of (+)-catechin Open
View article: Sucrose phosphorylase from<i>Alteromonas mediterranea</i>: structural insight into the regioselective α-glucosylation of (+)-catechin
Sucrose phosphorylase from<i>Alteromonas mediterranea</i>: structural insight into the regioselective α-glucosylation of (+)-catechin Open
Sucrose phosphorylases, through transglycosylation reactions, are interesting enzymes that can transfer regioselectively glucose from sucrose, the donor substrate, onto acceptors like flavonoids to form glycoconjugates and hence modulate t…
View article: Enzymatic synthesis, characterization and molecular docking of a new functionalized polyphenol: Resveratrol-3,4′-⍺-diglucoside
Enzymatic synthesis, characterization and molecular docking of a new functionalized polyphenol: Resveratrol-3,4′-⍺-diglucoside Open
Transglucosylation of resveratrol by the Q345F variant of sucrose phosphorylase from Bifidobacterium adolescentis (BaSP) was extensively studied during the last decade. Indeed, Q345F is able to catalyze the synthesis of resveratrol-3-O-⍺-D…
View article: Enzymatic Synthesis, Characterization and Molecular Docking of a New Functionalized Polyphenol: Resveratrol-3,4’-⍺-Diglucoside
Enzymatic Synthesis, Characterization and Molecular Docking of a New Functionalized Polyphenol: Resveratrol-3,4’-⍺-Diglucoside Open