Marie Didembourg
YOU?
Author Swipe
View article: Venous Thromboembolism Risk Associated with Relugolix-Estradiol-Norethisterone Acetate Combination Therapy
Venous Thromboembolism Risk Associated with Relugolix-Estradiol-Norethisterone Acetate Combination Therapy Open
Background Relugolix, an oral gonadotropin-releasing hormone (GnRH) receptor antagonist, is effective in treating uterine myomas and endometriosis. However, concerns persist regarding the venous thromboembolism (VTE) risk associated with i…
View article: Impact of asundexian on a panel of coagulation assays
Impact of asundexian on a panel of coagulation assays Open
Despite this study including a comprehensive panel of coagulation assays, asundexian may still affect other coagulation assays not assessed here. Further investigations in patients treated with asundexian are therefore warranted.
View article: Evaluation of neutralizing antibody titers against SARS-CoV-2 JN.1 omicron subvariant during pregnancy - A case series study
Evaluation of neutralizing antibody titers against SARS-CoV-2 JN.1 omicron subvariant during pregnancy - A case series study Open
NAb titers change dynamically during pregnancy, increasing then decreasing. Most pregnant women were asymptomatic and NAbs were effectively transferred to the fetus when infection or vaccination occurred near delivery. These findings highl…
View article: Are natural estrogens used in contraception at lower risk of venous thromboembolism than synthetic ones? A systematic literature review and meta-analysis
Are natural estrogens used in contraception at lower risk of venous thromboembolism than synthetic ones? A systematic literature review and meta-analysis Open
Background Venous thromboembolism (VTE) poses a significant global health challenge, notably exacerbated by the use of combined oral contraceptives (COCs). Evidence mainly focuses on the type of progestogen used in COCs to establish the in…
View article: Corrigendum to “Asundexian in atrial fibrillation: Can pharmacodynamic data explain the failure?” [Thromb. Res. 236 (2024) 236–239 TR_8963]
Corrigendum to “Asundexian in atrial fibrillation: Can pharmacodynamic data explain the failure?” [Thromb. Res. 236 (2024) 236–239 TR_8963] Open
View article: Asundexian in atrial fibrillation: Can pharmacodynamic data explain the failure?
Asundexian in atrial fibrillation: Can pharmacodynamic data explain the failure? Open
View article: Hemostatic imbalance induced by tamoxifen in estrogen receptor‐positive breast cancer patients: An observational study
Hemostatic imbalance induced by tamoxifen in estrogen receptor‐positive breast cancer patients: An observational study Open
Background Estrogen receptor (ER)‐positive (ER+) breast cancer accounts for approximately 75% of all breast cancers. Tamoxifen, a selective estrogen receptor modulator, is the standard adjuvant treatment. Although better tolerated than aro…
View article: Low thrombin generation in postmenopausal women using estetrol
Low thrombin generation in postmenopausal women using estetrol Open
The intake of E4 15 mg for 12 weeks led to significant but not clinically relevant changes compared to baseline as the mean values (±95% CI of the mean) remained within reference ranges, demonstrating a neutral profile of this estrogen on …
View article: Evaluation of Neutralizing Antibody Titers Against Sars-Cov-2 Jn.1 Omicron Subvariant During Pregnancy - a Case Series Study
Evaluation of Neutralizing Antibody Titers Against Sars-Cov-2 Jn.1 Omicron Subvariant During Pregnancy - a Case Series Study Open
View article: PB1502 Hemostatic Imbalance Associated with Tamoxifen in Estrogen Receptor-Positive Breast Cancer Patients: An Observational Study
PB1502 Hemostatic Imbalance Associated with Tamoxifen in Estrogen Receptor-Positive Breast Cancer Patients: An Observational Study Open
Conclusion(s):Estrogen use in this transgender cohort was frequent, and although not significantly associated with CTE, a trend towards higher risk was observed.Even in young transgender women, addressing modifiable cardiovascular risk fac…
View article: Feasibility of a mean platelet volume standard: an international council for standardization in hematology (ICSH) inter-laboratory study
Feasibility of a mean platelet volume standard: an international council for standardization in hematology (ICSH) inter-laboratory study Open
We have evaluated a commercial-fixed porcine platelet preparation (with and without added fixed human red blood cells (RBC)) for the potential standardization of mean platelet volume (MPV) measurements. The standards (Biotechne) were distr…
View article: Analytical Sensitivity of Six SARS-CoV-2 Rapid Antigen Tests for Omicron versus Delta Variant
Analytical Sensitivity of Six SARS-CoV-2 Rapid Antigen Tests for Omicron versus Delta Variant Open
Rapid antigen detection (RAD) tests are commonly used for the diagnosis of SARS-CoV-2 infections. However, with the continuous emergence of new variants of concern (VOC), presenting various mutations potentially affecting the nucleocapsid …
View article: Analytical performance of the endogenous thrombin potential–based activated protein C resistance assay on the automated ST Genesia system
Analytical performance of the endogenous thrombin potential–based activated protein C resistance assay on the automated ST Genesia system Open
View article: Analytical Sensitivity of Five SARS-CoV-2 Rapid Antigen Tests for Omicron Versus Delta Variant
Analytical Sensitivity of Five SARS-CoV-2 Rapid Antigen Tests for Omicron Versus Delta Variant Open
Rapid antigen detection tests (RAD) are commonly used for the diagnosis of SARS-CoV-2 infections. However, with the continuous emergence of new variants of concern (VOC) presenting various mutations potentially affecting the nucleocapsid p…
View article: Effect of tissue factor pathway inhibitor on thrombin generation assay
Effect of tissue factor pathway inhibitor on thrombin generation assay Open
Among the authors, J. Douxfils is CEO and founder of QUALIblood s.a., a contract research organization manufacturing the DP-Filter, is co-inventor of the DP-Filter (patent application number: PCT/ET2019/ 052903), and reports personal fees …
View article: Interlaboratory variability of activated protein C resistance using the ETP‐based APC resistance assay
Interlaboratory variability of activated protein C resistance using the ETP‐based APC resistance assay Open
View article: Study of in vitro thrombin generation after neutralization of heparin
Study of in vitro thrombin generation after neutralization of heparin Open
Introduction Thrombin generation (TG) documents hypercoagulability. TG in platelet‐poor plasma is exquisitely sensitive to heparins, which thus must be neutralized before testing. Heparinase and hexadimethrine bromide (polybrene) have been…
View article: Influence of C-reactive protein on thrombin generation assay
Influence of C-reactive protein on thrombin generation assay Open
To the editors, A close association between inflammatory state,C-reactive protein (CRP) and thromboembolic eventshas been described at least a decade ago [1] but hasresurfaced recently with the outbreak of the severe acuterespiratory syndr…
View article: Influence of Tissue-Factor Pathway Inhibitor on Thrombin Generation Assay
Influence of Tissue-Factor Pathway Inhibitor on Thrombin Generation Assay Open
Background : Tissue-factor pathway inhibitor (TFPI) is an anticoagulant protein that exerts its activity by forming an inactive FXa-TFPITF-FVIIa quaternary complex. In plasma, TFPI is normally found at a concentration of about 70 ng/mL but…
View article: Characteristics of L-PRP preparations for treating Achilles tendon rupture within the PATH-2 study
Characteristics of L-PRP preparations for treating Achilles tendon rupture within the PATH-2 study Open
Platelet-rich plasma (PRP) is an autologous preparation that has been claimed to improve healing and mechanobiological properties of tendons both in vitro and in vivo. In this sub-study from the PATH-2 (PRP in Achilles Tendon Healing-2) tr…