Marie Eckerström
YOU?
Author Swipe
View article: Depressive Symptoms and Amyloid Pathology
Depressive Symptoms and Amyloid Pathology Open
Importance Depressive symptoms are associated with cognitive decline in older individuals. Uncertainty about underlying mechanisms hampers diagnostic and therapeutic efforts. This large-scale study aimed to elucidate the association betwee…
View article: Demographically adjusted Rey–Osterrieth Complex Figure Test norms in a Swedish and Norwegian cohort aged 49–77 years and comparison with North American norms
Demographically adjusted Rey–Osterrieth Complex Figure Test norms in a Swedish and Norwegian cohort aged 49–77 years and comparison with North American norms Open
Introduction The Rey–Osterrieth Complex Figure Test (RCFT) is one of the most commonly used neuropsychological tests in Sweden and Norway. However, no publications provide normative data for this population. The objective of this study was…
View article: Improving validity of the trail making test with alphabet support
Improving validity of the trail making test with alphabet support Open
Objective The Trail Making Test (TMT) is commonly used worldwide to evaluate cognitive decline and car driving ability. However, it has received critique for its dependence on the Latin alphabet and thus, the risk of misclassifying some pa…
View article: Regression-based cognitive change norms applied in biochemically defined predementia Alzheimer’s disease.
Regression-based cognitive change norms applied in biochemically defined predementia Alzheimer’s disease. Open
We present 2-year cognitive change norms for adults between 41 and 84 years, adjusted for practice and demographics. A web-based change norm calculator is provided. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
View article: Regression‐based normative data for the Rey Auditory Verbal Learning Test in Norwegian and Swedish adults aged 49–79 and comparison with published norms
Regression‐based normative data for the Rey Auditory Verbal Learning Test in Norwegian and Swedish adults aged 49–79 and comparison with published norms Open
Objective: The Rey Auditory Verbal Learning Test (RAVLT) is a widely used measure of episodic verbal memory. To our knowledge, culturally adapted and demographically adjusted norms for the RAVLT are currently not available for Norwegian an…
View article: Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum
Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum Open
This study found that CSF-based estimates using adjusted data-driven cutoffs were up to 10% higher than PET-based estimates in people without dementia, whereas the results were similar among people with dementia. This finding suggests that…
View article: Characteristics of subjective cognitive decline associated with amyloid positivity
Characteristics of subjective cognitive decline associated with amyloid positivity Open
Introduction The evidence for characteristics of persons with subjective cognitive decline (SCD) associated with amyloid positivity is limited. Methods In 1640 persons with SCD from 20 Amyloid Biomarker Study cohort, we investigated the as…
View article: Self‐reported cognitive impairment and daily life functioning 7–12 years after seeking care for stress‐related exhaustion
Self‐reported cognitive impairment and daily life functioning 7–12 years after seeking care for stress‐related exhaustion Open
The overall aim of this study was to investigate self‐reported cognitive difficulties, daily life activities, and health/sleep factors in former patients with exhaustion disorder (ED) who still fulfill the clinical criteria for exhaustion …
View article: Using a Discourse Task to Explore Semantic Ability in Persons With Cognitive Impairment
Using a Discourse Task to Explore Semantic Ability in Persons With Cognitive Impairment Open
This paper uses a discourse task to explore aspects of semantic production in persons with various degree of cognitive impairment and healthy controls. The purpose of the study was to test if an in-depth semantic analysis of a cognitive-li…
View article: Evaluation of the ATN model in a longitudinal memory clinic sample with different underlying disorders
Evaluation of the ATN model in a longitudinal memory clinic sample with different underlying disorders Open
Introduction To evaluate the usefulness of the 2018 NIA‐AA (National Institute on Aging and Alzheimer's Association) research framework in a longitudinal memory clinic study with different clinical outcomes and underlying disorders. Method…
View article: Cognitive impairment without altered levels of cerebrospinal fluid biomarkers in patients with encephalitis caused by varicella-zoster virus: a pilot study
Cognitive impairment without altered levels of cerebrospinal fluid biomarkers in patients with encephalitis caused by varicella-zoster virus: a pilot study Open
Varicella-zoster virus (VZV) is one of the most common agents causing viral infections of the central nervous system (CNS). VZV encephalitis is associated with severe neurological sequelae, despite antiviral treatment. Cognitive impairment…
View article: Regression‐based normative data for the Rey Auditory Verbal Learning Test in Norwegian and Swedish adults ages 40 to 80
Regression‐based normative data for the Rey Auditory Verbal Learning Test in Norwegian and Swedish adults ages 40 to 80 Open
Background Adequate memory assessment is important in neuropsychological evaluation of middle‐aged and older adults with suspected mild cognitive impairment (MCI) and/or Alzheimer’s disease. The Rey Auditory Verbal Learning Test (RAVLT) is…
View article: Predictive and diagnostic utility of brief neuropsychological assessment in detecting Alzheimer’s pathology and progression to dementia.
Predictive and diagnostic utility of brief neuropsychological assessment in detecting Alzheimer’s pathology and progression to dementia. Open
Objective: To assess the role of brief neuropsychological assessments in prediction and identification of Alzheimer's disease (AD) pathology and progression to AD dementia. Method: Adults (N = 255; range = 40-81 years) with self-reported c…
View article: Demographically adjusted trail making test norms in a Scandinavian sample from 41 to 84 years
Demographically adjusted trail making test norms in a Scandinavian sample from 41 to 84 years Open
We here propose demographically adjusted norms for the TMT for ages 41 through 84 years based on a Scandinavian sample. We also present the regression-based derived measure TMT-β which may resolve issues with the conventional TMT B-A measu…
View article: Voice quality and speech fluency distinguish individuals with Mild Cognitive Impairment from Healthy Controls
Voice quality and speech fluency distinguish individuals with Mild Cognitive Impairment from Healthy Controls Open
Mild Cognitive Impairment (MCI) is a syndrome characterized by cognitive decline greater than expected for an individual's age and education level. This study aims to determine whether voice quality and speech fluency distinguish patients …
View article: Automated speech analysis enables MCI diagnosis
Automated speech analysis enables MCI diagnosis Open
Mild Cognitive Impairment (MCI) is a condition characterized by cognitive decline greater than expected for an individual's age and education level. In this study, we are investigating whether acoustic properties of speech production can i…
View article: Characteristic Biomarker and Cognitive Profile in Incipient Mixed Dementia
Characteristic Biomarker and Cognitive Profile in Incipient Mixed Dementia Open
Background: Research has shown that mixed dementia is more common than previously believed but little is known of its early stages. Objective: To examine if incipient mixed dementia can be differentiated from incipient Alzheimer’s disease …
View article: Effects of Cognitive Impairment on vowel duration effects of Cognitive Impairment on vowel duration
Effects of Cognitive Impairment on vowel duration effects of Cognitive Impairment on vowel duration Open
Mild cognitive impairment (MCI) is a neurological condition, which is characterized by a noticeable decline of cognitive abilities, including communicative and linguistic skills.In this study, we have measured the duration of vowels produc…
View article: Neurodegeneration and the Gothenburg MCI study
Neurodegeneration and the Gothenburg MCI study Open
Mild cognitive impairment (MCI) is the stage between the expected cognitive decline of a normal aging population and the more serious decline of dementia.Typically, the performance of a cognitive test is considered impaired if it is =>1.5 …
View article: Predicting MCI Status From Multimodal Language Data Using Cascaded Classifiers
Predicting MCI Status From Multimodal Language Data Using Cascaded Classifiers Open
Recent work has indicated the potential utility of automated language analysis for the detection of mild cognitive impairment (MCI). Most studies combining language processing and machine learning for the prediction of MCI focus on a singl…
View article: P3‐479: NEUROPSYCHOLOGY AND <sup>99M</sup>TC‐HMPAO SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY FINDINGS FROM THE GOTHENBURG MCI STUDY
P3‐479: NEUROPSYCHOLOGY AND <sup>99M</sup>TC‐HMPAO SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY FINDINGS FROM THE GOTHENBURG MCI STUDY Open
Neuropsychological assessment and cerebral blood flow (CBF) single photon emission computed tomography (SPECT) are both tools with well-established sensitivity to detect early functional changes due to Alzheimer's disease (AD) and related …
View article: Temporal Analysis of the Semantic Verbal Fluency Task in Persons with Subjective and Mild Cognitive Impairment
Temporal Analysis of the Semantic Verbal Fluency Task in Persons with Subjective and Mild Cognitive Impairment Open
Nicklas Linz, Kristina Lundholm Fors, Hali Lindsay, Marie Eckerström, Jan Alexandersson, Dimitrios Kokkinakis. Proceedings of the Sixth Workshop on Computational Linguistics and Clinical Psychology. 2019.
View article: Identification of Mild Cognitive Impairment From Speech in Swedish Using Deep Sequential Neural Networks
Identification of Mild Cognitive Impairment From Speech in Swedish Using Deep Sequential Neural Networks Open
While people with mild cognitive impairment (MCI) portray noticeably incipient memory difficulty in remembering events and situations along with problems in decision making, planning, and finding their way in familiar environments, detaile…
View article: Increased Risk of Dementia in Subjective Cognitive Decline if CT Brain Changes are Present
Increased Risk of Dementia in Subjective Cognitive Decline if CT Brain Changes are Present Open
Our observations add clinical value to the use of SCD and CT to select relevant populations for interventions against dementia, but more stringent screening methods are necessary to reach individuals at risk.
View article: Better prognostic accuracy in younger mild cognitive impairment patients with more years of education
Better prognostic accuracy in younger mild cognitive impairment patients with more years of education Open
Introduction Age and years of education influence the risk of dementia and may impact the prognostic accuracy of mild cognitive impairment subtypes. Methods Memory clinic patients without dementia (N = 358, age 64.0 ± 7.9) were stratified …
View article: Subjective cognitive decline in memory clinic patients - characteristics and clinical relevance
Subjective cognitive decline in memory clinic patients - characteristics and clinical relevance Open
Subjective cognitive decline (SCD) refers to concerns – symptoms - regarding one’s\ncognitive functioning, in the absence of objective evidence of impairment. SCD has\nbeen described as a possible stage preceding mild cognitive impairment …
View article: Subjective Cognitive Impairment Is a Predominantly Benign Condition in Memory Clinic Patients Followed for 6 Years: The Gothenburg-Oslo MCI Study
Subjective Cognitive Impairment Is a Predominantly Benign Condition in Memory Clinic Patients Followed for 6 Years: The Gothenburg-Oslo MCI Study Open
Background/Aims: In the quest for prevention or treatment, there is a need to find early markers for preclinical dementia. This study observed memory clinic patients with subjective cognitive impairment (SCI) and normal cognitive function …
View article: Longitudinal evaluation of criteria for subjective cognitive decline and preclinical Alzheimer's disease in a memory clinic sample
Longitudinal evaluation of criteria for subjective cognitive decline and preclinical Alzheimer's disease in a memory clinic sample Open
Introduction Subjective cognitive decline (SCD) and biomarker‐based “at‐risk” concepts such as “preclinical” Alzheimer's disease (AD) have been developed to predict AD dementia before objective cognitive impairment is detectable. We longit…