Marie Fablet
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View article: Transposable element expression is associated with sex chromosome number in humans
Transposable element expression is associated with sex chromosome number in humans Open
Why women live longer than men is still an open question in human biology. Sex chromosomes have been proposed to play a role in the observed sex gap in longevity, and the Y male chromosome has been suspected of having a potential toxic gen…
View article: Exploring the role of transposable elements to sex gap in longevity in <i>Drosophila</i> species
Exploring the role of transposable elements to sex gap in longevity in <i>Drosophila</i> species Open
In Drosophila , like in many other animal species, females tend to live longer than males, a phenomenon known as sex gap in longevity (SGL). One possible explanation for this phenomenon could be related to the activity of transposable elem…
View article: Identification and quantification of transposable element transcripts using Long-Read RNA-seq in Drosophila germline tissues
Identification and quantification of transposable element transcripts using Long-Read RNA-seq in Drosophila germline tissues Open
Transposable elements (TEs) are repeated DNA sequences potentially able to move throughout the genome. In addition to their inherent mutagenic effects, TEs can disrupt nearby genes by donating their intrinsic regulatory sequences, for inst…
View article: Identification and quantification of transposable element transcripts using Long-Read RNA-seq in Drosophila germline tissues - Processed Data, Scripts & Supplementary Material
Identification and quantification of transposable element transcripts using Long-Read RNA-seq in Drosophila germline tissues - Processed Data, Scripts & Supplementary Material Open
This deposit contains the processed data (.bam files) for the preprint https://doi.org/10.1101/2023.05.27.542554Scripts to produce these files, as well as genome and annotations to explore this data in IGV are available at https://gitlab.i…
View article: Effects of Arboviral Infections on Transposable Element Transcript Levels in <i>Aedes aegypti</i>
Effects of Arboviral Infections on Transposable Element Transcript Levels in <i>Aedes aegypti</i> Open
Transposable elements are mobile repeated sequences found in all genomes. Transposable elements are controlled by RNA interference pathways in most organisms, and this control involves the PIWI-interacting RNA pathway and the small interfe…
View article: Intricate interactions between antiviral immunity and transposable element control in<i>Drosophila</i>
Intricate interactions between antiviral immunity and transposable element control in<i>Drosophila</i> Open
Transposable elements (TEs) are parasite DNA sequences that are controlled by RNA interference pathways in many organisms. In insects, antiviral immunity is also achieved by the action of small RNAs. In the present study, we analyzed the i…
View article: Identification and quantification of transposable element transcripts using Long-Read RNA-seq in Drosophila germline tissues - Processed Data
Identification and quantification of transposable element transcripts using Long-Read RNA-seq in Drosophila germline tissues - Processed Data Open
This deposit contains the processed data (.bam files) for the preprint https://doi.org/10.1101/2023.05.27.542554Scripts to produce these files, as well as genome and annotations to explore this data in IGV are available at https://gitlab.i…
View article: Impact of Heat Stress on Transposable Element Expression and Derived Small RNAs in <i>Drosophila subobscura</i>
Impact of Heat Stress on Transposable Element Expression and Derived Small RNAs in <i>Drosophila subobscura</i> Open
Global warming is forcing insect populations to move and adapt, triggering adaptive genetic responses. Thermal stress is known to alter gene expression, repressing the transcription of active genes, and inducing others, such as those encod…
View article: A Quantitative, Genome-Wide Analysis in <i>Drosophila</i> Reveals Transposable Elements’ Influence on Gene Expression Is Species-Specific
A Quantitative, Genome-Wide Analysis in <i>Drosophila</i> Reveals Transposable Elements’ Influence on Gene Expression Is Species-Specific Open
Transposable elements (TEs) are parasite DNA sequences that are able to move and multiply along the chromosomes of all genomes. They can be controlled by the host through the targeting of silencing epigenetic marks, which may affect the ch…
View article: ChimeraTE: a pipeline to detect chimeric transcripts derived from genes and transposable elements
ChimeraTE: a pipeline to detect chimeric transcripts derived from genes and transposable elements Open
Transposable elements (TEs) produce structural variants and are considered an important source of genetic diversity. Notably, TE-gene fusion transcripts, i.e. chimeric transcripts, have been associated with adaptation in several species. H…
View article: Transposable element expression with variation in sex chromosome number: insights into a toxic Y effect on human longevity
Transposable element expression with variation in sex chromosome number: insights into a toxic Y effect on human longevity Open
A bstract Why women live longer than men is still an open question in human biology. Sex chromosomes have been proposed to play a role in the observed sex gap in longevity, and the Y male chromosome has been suspected of having a potential…
View article: ChimeraTE: A pipeline to detect chimeric transcripts derived from genes and transposable elements
ChimeraTE: A pipeline to detect chimeric transcripts derived from genes and transposable elements Open
Transposable elements (TEs) produce structural variants and are considered an important source of genetic diversity. Notably, TE-gene fusion transcripts, i.e., chimeric transcripts, have been associated with adaptation in several species. …
View article: High Stability of the Epigenome in<i>Drosophila</i>Interspecific Hybrids
High Stability of the Epigenome in<i>Drosophila</i>Interspecific Hybrids Open
Interspecific hybridization is often seen as a genomic stress that may lead to new gene expression patterns and deregulation of transposable elements (TEs). The understanding of expression changes in hybrids compared with parental species …
View article: A quantitative, genome-wide analysis in<i>Drosophila</i>reveals transposable elements’ influence on gene expression is species-specific
A quantitative, genome-wide analysis in<i>Drosophila</i>reveals transposable elements’ influence on gene expression is species-specific Open
Transposable elements (TEs) are parasite DNA sequences that are able to move and multiply along the chromosomes of all genomes. They can be controlled by the host through the targeting of silencing epigenetic marks, which may affect the ch…
View article: Genome annotations of Drosophila melanogaster and Drosophila simulans wild-type strains from long read sequencing assemblies
Genome annotations of Drosophila melanogaster and Drosophila simulans wild-type strains from long read sequencing assemblies Open
Genome assemblies were performed for eight wild-type strains of Drosophila melanogaster and Drosophila simulans from Oxford Nanopore long read sequencing (please refer to Mohamed et al. Cells 2020 (doi:10.3390/cells9081776)). Assemblies we…
View article: Genome annotations of Drosophila melanogaster and Drosophila simulans wild-type strains from long read sequencing assemblies
Genome annotations of Drosophila melanogaster and Drosophila simulans wild-type strains from long read sequencing assemblies Open
Genome assemblies were performed for eight wild-type strains of Drosophila melanogaster and Drosophila simulans from Oxford Nanopore long read sequencing (please refer to Mohamed et al. Cells 2020 (doi:10.3390/cells9081776)). Assemblies we…
View article: Genome annotations of Drosophila melanogaster and Drosophila simulans wild-type strains from long read sequencing assemblies
Genome annotations of Drosophila melanogaster and Drosophila simulans wild-type strains from long read sequencing assemblies Open
Genome assemblies were performed for eight wild-type strains of Drosophila melanogaster and Drosophila simulans from Oxford Nanopore long read sequencing (please refer to Mohamed et al. Cells 2020 (doi:10.3390/cells9081776)). Assemblies we…
View article: Transposable Element Expression and Regulation Profile in Gonads of Interspecific Hybrids of Drosophila arizonae and Drosophila mojavensis wrigleyi
Transposable Element Expression and Regulation Profile in Gonads of Interspecific Hybrids of Drosophila arizonae and Drosophila mojavensis wrigleyi Open
Interspecific hybridization may lead to sterility and/or inviability through differential expression of genes and transposable elements (TEs). In Drosophila, studies have reported massive TE mobilization in hybrids from interspecific cross…
View article: Infections by Transovarially Transmitted DMelSV in <i>Drosophila</i> Have No Impact on Ovarian Transposable Element Transcripts but Increase Their Amounts in the Soma
Infections by Transovarially Transmitted DMelSV in <i>Drosophila</i> Have No Impact on Ovarian Transposable Element Transcripts but Increase Their Amounts in the Soma Open
Transposable elements (TEs) are genomic parasites, which activity is tightly controlled in germline cells. Using Sindbis virus, it was recently demonstrated that viral infections affect TE transcript amounts in somatic tissues. However, th…
View article: Phenotypic and Transcriptomic Responses to Stress Differ According to Population Geography in an Invasive Species
Phenotypic and Transcriptomic Responses to Stress Differ According to Population Geography in an Invasive Species Open
Adaptation to rapid environmental changes must occur within a short-time scale. In this context, studies of invasive species may provide insights into the underlying mechanisms of rapid adaptation as these species have repeatedly encounter…
View article: The Worldwide Invasion of <i>Drosophila suzukii</i> Is Accompanied by a Large Increase of Transposable Element Load and a Small Number of Putatively Adaptive Insertions
The Worldwide Invasion of <i>Drosophila suzukii</i> Is Accompanied by a Large Increase of Transposable Element Load and a Small Number of Putatively Adaptive Insertions Open
Transposable elements (TEs) are ubiquitous and mobile repeated sequences. They are major determinants of host fitness. Here, we characterized the TE content of the spotted wing fly Drosophila suzukii. Using a recently improved genome assem…
View article: The worldwide invasion of<i>Drosophila suzukii</i>is accompanied by a large increase of transposable element load and a small number of putatively adaptive insertions
The worldwide invasion of<i>Drosophila suzukii</i>is accompanied by a large increase of transposable element load and a small number of putatively adaptive insertions Open
Transposable Elements (TEs) are ubiquitous and mobile repeated sequences. They are major determinants of host fitness. Here, we portrayed the TE content of the spotted wing fly Drosophila suzukii . Using a recently improved genome assembly…
View article: Phenotypic and transcriptomic responses to stress differ according to population geography in an invasive species
Phenotypic and transcriptomic responses to stress differ according to population geography in an invasive species Open
Background Adaptation to rapid environmental changes must occur within a short time scale. In this context, studies of invasive species may provide insights into the underlying mechanisms of rapid adaptation as these species have repeatedl…
View article: A Transposon Story: From TE Content to TE Dynamic Invasion of Drosophila Genomes Using the Single-Molecule Sequencing Technology from Oxford Nanopore
A Transposon Story: From TE Content to TE Dynamic Invasion of Drosophila Genomes Using the Single-Molecule Sequencing Technology from Oxford Nanopore Open
Transposable elements (TEs) are the main components of genomes. However, due to their repetitive nature, they are very difficult to study using data obtained with short-read sequencing technologies. Here, we describe an efficient pipeline …
View article: Transposable elements in Drosophila
Transposable elements in Drosophila Open
Drosophila has been studied as a biological model for many years and many discoveries in biology rely on this species. Research on transposable elements (TEs) is not an exception. Drosophila has contributed significantly to our knowledge o…
View article: Viral infection impacts transposable element transcript amounts in <i>Drosophila</i>
Viral infection impacts transposable element transcript amounts in <i>Drosophila</i> Open
Transposable elements (TEs) are genomic parasites that are found in all genomes, some of which display sequence similarity to certain viruses. In insects, TEs are controlled by the Piwi-interacting small interfering RNA (piRNA) pathway in …
View article: Dynamic Interactions Between the Genome and an Endogenous Retrovirus: <i>Tirant</i> in <i>Drosophila simulans</i> Wild-Type Strains
Dynamic Interactions Between the Genome and an Endogenous Retrovirus: <i>Tirant</i> in <i>Drosophila simulans</i> Wild-Type Strains Open
All genomes contain repeated sequences that are known as transposable elements (TEs). Among these are endogenous retroviruses (ERVs), which are sequences similar to retroviruses and are transmitted across generations from parent to progeny…
View article: The somatic piRNA pathway controls germline transposition over generations
The somatic piRNA pathway controls germline transposition over generations Open
Transposable elements (TEs) are parasitic DNA sequences that threaten genome integrity by replicative transposition in host gonads. The Piwi-interacting RNAs (piRNAs) pathway is assumed to maintain Drosophila genome homeostasis by downregu…