Marie Klintman
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View article: FGF/FGFR1 system in paired breast tumor-adjacent and tumor tissues, associations with mammographic breast density and tumor characteristics
FGF/FGFR1 system in paired breast tumor-adjacent and tumor tissues, associations with mammographic breast density and tumor characteristics Open
Introduction Mammographic breast density (MBD) is an established breast cancer risk factor, yet the underlying molecular mechanisms remain to be deciphered. Fibroblast growth factor receptor 1 (FGFR1) amplification is associated with breas…
View article: Supplementary Figure S3a-x from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Supplementary Figure S3a-x from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease Open
Kaplan-Meier curves with probability of relapse, with genes divided into tertiles for all 24 genes for the end-point TTR for (a) ACACB (b) ALDHA1 (c) AURKA (d) BCL2 (e) BCL2L1 (f) CD3D (g) CD44 (h) CXCL14 (i) DECORIN (j) DUSP4 (k) ERBB2 (l…
View article: Supplementary Figure S2 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Supplementary Figure S2 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease Open
Correlation coefficient matrix between of genes and IHC ER, PgR, and Ki67. Shades of blue indicate a positive correlation, and shades of orange a negative correlation.
View article: Supplementary Table S1 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Supplementary Table S1 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease Open
List of the selected genes, the associated biological process, prognostic and/or treatment predictive value in previous studies, and biological function. Apart from the 22 gene in the list below, the clinically established prognostic and t…
View article: Supplementary Table S3 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Supplementary Table S3 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease Open
Association between DUSP4 expression and Ras-ERK pathway proteins measured by reverse-phase protein arrays (RPPA) in 633 breast tumours from TCGA
View article: Supplementary Table S1 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Supplementary Table S1 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease Open
List of the selected genes, the associated biological process, prognostic and/or treatment predictive value in previous studies, and biological function. Apart from the 22 gene in the list below, the clinically established prognostic and t…
View article: Table and Figure legends for Supplementary data from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Table and Figure legends for Supplementary data from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease Open
Table and Figure legends for Supplementary data
View article: Supplementar yFigure S1 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Supplementar yFigure S1 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease Open
Consort diagram
View article: Supplementary Figure S2 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Supplementary Figure S2 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease Open
Correlation coefficient matrix between of genes and IHC ER, PgR, and Ki67. Shades of blue indicate a positive correlation, and shades of orange a negative correlation.
View article: Data from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Data from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease Open
Purpose: The primary aim was to derive evidence for or against the clinical importance of several biologic processes in patients treated with neoadjuvant chemotherapy (NAC) by assessing expression of selected genes with prior implications …
View article: Supplementary Table S3 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Supplementary Table S3 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease Open
Association between DUSP4 expression and Ras-ERK pathway proteins measured by reverse-phase protein arrays (RPPA) in 633 breast tumours from TCGA
View article: Supplementary Figure S4 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Supplementary Figure S4 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease Open
Association between CD3D mRNA expression values and IHC assessment of CD3D in residual disease
View article: Table and Figure legends for Supplementary data from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Table and Figure legends for Supplementary data from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease Open
Table and Figure legends for Supplementary data
View article: Supplementary Figure S3a-x from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Supplementary Figure S3a-x from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease Open
Kaplan-Meier curves with probability of relapse, with genes divided into tertiles for all 24 genes for the end-point TTR for (a) ACACB (b) ALDHA1 (c) AURKA (d) BCL2 (e) BCL2L1 (f) CD3D (g) CD44 (h) CXCL14 (i) DECORIN (j) DUSP4 (k) ERBB2 (l…
View article: Supplementary Table S2 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Supplementary Table S2 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease Open
Multivariable fixed model consisting of clinical ER, PgR, HER2, and Ki67 (IHC4), adjusted for one gene at a time with the end-point time to recurrence.
View article: Supplementary Table S2 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Supplementary Table S2 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease Open
Multivariable fixed model consisting of clinical ER, PgR, HER2, and Ki67 (IHC4), adjusted for one gene at a time with the end-point time to recurrence.
View article: Supplementar yFigure S1 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Supplementar yFigure S1 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease Open
Consort diagram
View article: Data from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Data from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease Open
Purpose: The primary aim was to derive evidence for or against the clinical importance of several biologic processes in patients treated with neoadjuvant chemotherapy (NAC) by assessing expression of selected genes with prior implications …
View article: Supplementary Figure S4 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease
Supplementary Figure S4 from Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease Open
Association between CD3D mRNA expression values and IHC assessment of CD3D in residual disease
View article: Postmenopausal overweight and breast cancer risk; results from the KARMA cohort
Postmenopausal overweight and breast cancer risk; results from the KARMA cohort Open
Purpose To study the risk of incident breast cancer and subtype-specific breast cancer in relation to excess body weight in a contemporary Swedish prospective cohort study, The Karolinska Mammography Project for Risk Prediction of Breast C…
View article: Physical Activity and Long-Term Risk of Breast Cancer, Associations with Time in Life and Body Composition in the Prospective Malmö Diet and Cancer Study
Physical Activity and Long-Term Risk of Breast Cancer, Associations with Time in Life and Body Composition in the Prospective Malmö Diet and Cancer Study Open
Being physically active as part of everyday life reduces breast cancer risk. Less is known whether the benefits of an active lifestyle differ depending on the timing of physical activity in life or anthropometric characteristics. The aim o…
View article: <b>Long-Term Prognostication for 20 114 Women With Small and Node-Negative Breast Cancer</b> <b>(T1abN0)</b>
<b>Long-Term Prognostication for 20 114 Women With Small and Node-Negative Breast Cancer</b> <b>(T1abN0)</b> Open
Background Although small, node-negative breast cancer (ie, T1abN0) constitutes 20% of all newly diagnosed breast cancers, data on prognosis and prognostic factors are limited. Methods We conducted a population-based cohort study including…
View article: Datasets and metadata supporting the published article: Prognostic implications of the expression levels of different immunoglobulin heavy chain-encoding RNAs in early breast cancer
Datasets and metadata supporting the published article: Prognostic implications of the expression levels of different immunoglobulin heavy chain-encoding RNAs in early breast cancer Open
In this study, the authors used RNA-Seq data from two local population-based breast cancer cohorts to determine the expression of IGJ (a gene encoding the J chain protein component of the antibodies IgM and IgA) and immunoglobulin heavy (I…
View article: Novel 18-gene signature for predicting relapse in ER-positive, HER2-negative breast cancer
Novel 18-gene signature for predicting relapse in ER-positive, HER2-negative breast cancer Open
The derived 10-year signature predicts risk of metastasis in patients with ER+/HER2- breast cancer similar to commercial signatures. The hypothesis that early and late prognostic signatures are significantly more informative than a single …
View article: Additional file 2: of Novel 18-gene signature for predicting relapse in ER-positive, HER2-negative breast cancer
Additional file 2: of Novel 18-gene signature for predicting relapse in ER-positive, HER2-negative breast cancer Open
Table S1. List of 585 candidate genes. Table S2. List and identifiers for the 747-patient microarray expression data cohort. Table S3. List of 454 Affymetrix probes studied. Table S4. List of 212 genes significantly prognostic (pâ
View article: Androgen Receptor in Stage I-II Primary Breast Cancer –Prognostic Value and Distribution in Subgroups
Androgen Receptor in Stage I-II Primary Breast Cancer –Prognostic Value and Distribution in Subgroups Open
AR is a weak, however, not independent prognostic factor for distant metastasis. Although the prognostic value of AR may be questionable, the study identified a subset of AR-positive triple-negative patients as being potential candidates f…