Martin Krämer
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View article: Quantitative comparison of T1, T2, T1ρ, and ADC for assessing age-related intervertebral disc degeneration
Quantitative comparison of T1, T2, T1ρ, and ADC for assessing age-related intervertebral disc degeneration Open
Age-related degeneration of intervertebral discs (IVDs) is a key contributor to chronic low back pain. In this study, we performed a multiparametric comparison of four quantitative MRI (qMRI) parameters-T1, T2, T1ρ, and the apparent diffus…
View article: AI-based HRCT quantification reveals DLCO and TLC as key determinants of ILD severity in connective tissue diseases
AI-based HRCT quantification reveals DLCO and TLC as key determinants of ILD severity in connective tissue diseases Open
Objective Interstitial lung disease (ILD) represents the most common and severe organ manifestation observed in patients diagnosed with connective tissue diseases (CTDs). The aim of this retrospective cross-sectional study was to identify …
View article: Lung ultrasound in children with cystic fibrosis – A new promising approach
Lung ultrasound in children with cystic fibrosis – A new promising approach Open
We could demonstrate that lung ultrasound is a sensitive and reliable method for assessing pulmonary changes in cystic fibrosis.
View article: Interstitial lung disease with and without pulmonary symptoms at the onset of inflammatory rheumatic disease - similarities and differences
Interstitial lung disease with and without pulmonary symptoms at the onset of inflammatory rheumatic disease - similarities and differences Open
Objective: Interstitial lung disease (ILD) is a common and serious organ manifestation in patients with inflammatory rheumatic disease (IRD), but it is uncertain whether there is a difference in ILD between symptomatic and asymptomatic pat…
View article: Image quality of virtual monochromatic and material density iodine images for evaluation of head and neck neoplasms using deep learning-based CT image reconstruction – A retrospective observational study
Image quality of virtual monochromatic and material density iodine images for evaluation of head and neck neoplasms using deep learning-based CT image reconstruction – A retrospective observational study Open
DECT using both DLIR and MAR for the generation of VMIs and MD iodine images resulted in higher subjective quality of oncologic head and neck images than ASIR-V-based SECT. Noise reduction and noise texture were best achieved with DLIR-bas…
View article: Toroidal embeddings of cubic projective plane obstructions
Toroidal embeddings of cubic projective plane obstructions Open
Work of Glover and Huneke shows that a cubic graph embeds into the real projective plane if and only if it does not contain one of six topological minors called cubic projective plane obstructions. Here we classify up to equivalence the em…
View article: Artificial intelligence-based quantification of pulmonary HRCT (AIqpHRCT) for the evaluation of interstitial lung disease in patients with inflammatory rheumatic diseases
Artificial intelligence-based quantification of pulmonary HRCT (AIqpHRCT) for the evaluation of interstitial lung disease in patients with inflammatory rheumatic diseases Open
High-resolution computed tomography (HRCT) is important for diagnosing interstitial lung disease (ILD) in inflammatory rheumatic disease (IRD) patients. However, visual ILD assessment via HRCT often has high inter-reader variability. Artif…
View article: Short-term outcome after treatment of talocrural instability in cats using modified type II transarticular external skeletal fixation
Short-term outcome after treatment of talocrural instability in cats using modified type II transarticular external skeletal fixation Open
Transarticular external skeletal fixation (TESF) is repeatedly used for temporary stabilisation of tarsal joint in cats. Hence, this study aimed to evaluate the use of temporary modified type II TESF for management of talocrural instabilit…
View article: Management of Elbow Luxation in Dogs and Cats: An Overview
Management of Elbow Luxation in Dogs and Cats: An Overview Open
Luxation of the elbow has been frequently reported in dogs and cats.It can occur in several forms lateral, medial, caudal luxation or Monteggia fracture.Several methods have been used for management of elbow luxation including closed or op…
View article: Iatrogenic air embolism: influence of air bubble size on cerebral infarctions in an experimental in vivo and numerical simulation model
Iatrogenic air embolism: influence of air bubble size on cerebral infarctions in an experimental in vivo and numerical simulation model Open
Background Cerebral infarctions resulting from iatrogenic air embolism (AE), mainly caused by small air bubbles, are a well-known and often overlooked event in endovascular interventions. Despite their significance, the underlying pathophy…
View article: Water-binding strength as regulator of extracellular-matrix mechanics enables detection of swelling-associated biophysical alterations using MRI
Water-binding strength as regulator of extracellular-matrix mechanics enables detection of swelling-associated biophysical alterations using MRI Open
Altered hygroscopic properties of the extracellular matrix (ECM), such as related to exudation, are characteristic for various pathologies including inflammation in injury, inherent swelling, or proteoglycan (PG) dysregulation. Mechanical …
View article: Perfusion and <scp><i>T</i><sub>2</sub></scp> Relaxation Time as Predictors of Severity and Outcome in Sepsis‐Associated Acute Kidney Injury: A Preclinical <scp>MRI</scp> Study
Perfusion and <span><i>T</i><sub>2</sub></span> Relaxation Time as Predictors of Severity and Outcome in Sepsis‐Associated Acute Kidney Injury: A Preclinical <span>MRI</span> Study Open
Background Preventing sepsis‐associated acute kidney injury (S‐AKI) can be challenging because it develops rapidly and is often asymptomatic. Probability assessment of disease progression for therapeutic follow‐up and outcome are important…
View article: Lung ultrasound in children and adolescents with long-term effects of COVID-19: Initial results
Lung ultrasound in children and adolescents with long-term effects of COVID-19: Initial results Open
Introduction Chronic health effects following acute COVID-19 are increasingly observed as the pandemic continues and are grouped under long COVID. Although the acute course of the COVID disease is often milder, long COVID also affects chil…
View article: Whole-body diffusion magnetic resonance imaging with simultaneous multi-slice excitation in children and adolescents
Whole-body diffusion magnetic resonance imaging with simultaneous multi-slice excitation in children and adolescents Open
Background Whole-body magnetic resonance imaging (WB-MRI) is an increasingly used guideline-based imaging modality for oncological and non-oncological pathologies during childhood and adolescence. While diffusion-weighted imaging (DWI), a …
View article: The Role of Femoral Head Size and Femoral Head Coverage in Dogs with and without Hip Dysplasia
The Role of Femoral Head Size and Femoral Head Coverage in Dogs with and without Hip Dysplasia Open
The subject of hip dysplasia in dogs is still current and preoccupies both animal owners and veterinarians. Major factors affecting the development of the disorder are hip laxity and incongruent joints. Many studies on etiology, pathogenes…
View article: Time-resolved velocity mapping at high magnetic fields: A preclinical comparison between stack‐of‐stars and cartesian 4D-Flow
Time-resolved velocity mapping at high magnetic fields: A preclinical comparison between stack‐of‐stars and cartesian 4D-Flow Open
Purpose: Prospectively-gated Cartesian 4D-flow (referred to as Cartesian-4D-flow) imaging suffers from long TE and intensified flow-related intravoxel-dephasing especially in preclinical ultra-high field MRI. The ultra-short-echo (UTE) 4D-…
View article: A novel free-breathing abdominal RAVE T2/T1 hybrid MRI sequence in patients with cystic fibrosis: Preliminary results
A novel free-breathing abdominal RAVE T2/T1 hybrid MRI sequence in patients with cystic fibrosis: Preliminary results Open
The abdominal radial RAVE T2/T1 hybrid sequence provided higher image quality and SNR than the T2HASTEsequence. Together with increased robustness against motion artifacts, the RAVE T2/T1 hybrid sequence appears to be a good tool for abdom…
View article: High-resolution CINE imaging of active guided knee motion using continuously acquired golden-angle radial MRI and rotary sensor information
High-resolution CINE imaging of active guided knee motion using continuously acquired golden-angle radial MRI and rotary sensor information Open
To explore and extend on dynamic imaging of joint motion, an MRI-safe device guiding knee motion with an attached rotary encoder was used in MRI measurements of multiple knee flexion-extension cycles using radial gradient echo imaging with…
View article: Investigation of Experimental Endovascular Air Embolisms Using a New Model for the Generation and Detection of Highly Calibrated Micro Air Bubbles
Investigation of Experimental Endovascular Air Embolisms Using a New Model for the Generation and Detection of Highly Calibrated Micro Air Bubbles Open
Background: Air embolism (AE), especially when affecting the brain, is an underrated and potentially life-threatening complication in various endovascular interventions. This study aims to investigate experimental AEs using a new model to …
View article: Pulmonary Arteriovenous Pressure Gradient and Time-Averaged Mean Velocity of Small Pulmonary Arteries Can Serve as Sensitive Biomarkers in the Diagnosis of Pulmonary Arterial Hypertension: A Preclinical Study by 4D-Flow MRI
Pulmonary Arteriovenous Pressure Gradient and Time-Averaged Mean Velocity of Small Pulmonary Arteries Can Serve as Sensitive Biomarkers in the Diagnosis of Pulmonary Arterial Hypertension: A Preclinical Study by 4D-Flow MRI Open
(1) Background: Pulmonary arterial hypertension (PAH) is a serious condition that is associated with many cardiopulmonary diseases. Invasive right heart catheterization (RHC) is currently the only method for the definitive diagnosis and fo…
View article: Genetic background of lumbosacral transitional vertebrae in German shepherd dogs
Genetic background of lumbosacral transitional vertebrae in German shepherd dogs Open
Objectives Estimation of genetic parameters of lumbosacral transitional vertebrae based on data derived from radiographic screening of 27,597 German shepherd dogs. Materials and Methods Results of radiographic screening for lumbosacral tra…