Pierre‐Marie Preux
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View article: DNA quality challenges in breast cancer samples from three low-middle income African countries: a straightforward protocol for research in cancer genomics
DNA quality challenges in breast cancer samples from three low-middle income African countries: a straightforward protocol for research in cancer genomics Open
Sub-Saharan African women often develop breast cancer at a younger age, with a high prevalence of aggressive subtypes such as triple-negative breast cancer and elevated mortality. Genetic factors may underlie these patterns, but African po…
View article: Knowledge, attitudes, and practices of final-year healthcare students in low- and middle-income countries regarding epilepsy, dementia, and psychiatric disorders
Knowledge, attitudes, and practices of final-year healthcare students in low- and middle-income countries regarding epilepsy, dementia, and psychiatric disorders Open
Purpose Prevalence of chronic brain disorders, including dementia, epilepsy, and psychiatric disorders, is increasing worldwide. This represents a major challenge for future healthcare professionnals, especially in Low- and Middle-Income C…
View article: Aortic stenosis and peripheral artery disease: Impact on mortality following transcatheter aortic valve replacement
Aortic stenosis and peripheral artery disease: Impact on mortality following transcatheter aortic valve replacement Open
PAD was independently associated with increased mortality in severe calcific AS. Importantly, this excess mortality among patients with PAD was not affected by the simultaneous presence of CAD. Similarly to patients with CAD, patients with…
View article: Epidemiology of peripheral neuropathies in sub-Saharan Africa from 2000 to 2020: systematic review and meta-analysis
Epidemiology of peripheral neuropathies in sub-Saharan Africa from 2000 to 2020: systematic review and meta-analysis Open
Introduction: Epidemiological studies on peripheral neuropathy (PN) in sub-Saharan Africa (SSA) have been conducted out in various target populations. This systematic review and meta-analysis aim to present and update available descriptive…
View article: Yara: An Ocean Virtual Environment for Research and Development of Autonomous Sailing Robots and Other Unmanned Surface Vessels
Yara: An Ocean Virtual Environment for Research and Development of Autonomous Sailing Robots and Other Unmanned Surface Vessels Open
International audience
View article: Cancer in Severe Mental Illness Patients: A Retrospective Study
Cancer in Severe Mental Illness Patients: A Retrospective Study Open
Objective Severe mental illness (SMI), including schizophrenia, bipolar disorder or depression, constitute a risk factor for premature death. SMI patients die more frequently and earlier of cancer than the general population. Chronic infla…
View article: Evaluating Interpretable Reinforcement Learning by Distilling Policies into Programs
Evaluating Interpretable Reinforcement Learning by Distilling Policies into Programs Open
There exist applications of reinforcement learning like medicine where policies need to be ''interpretable'' by humans. User studies have shown that some policy classes might be more interpretable than others. However, it is costly to cond…
View article: Impact of a preoperative child-parent accompaniment procedure on the anxiety of children aged 5 to 12 with scheduled surgery: a pilot comparative randomized trial.
Impact of a preoperative child-parent accompaniment procedure on the anxiety of children aged 5 to 12 with scheduled surgery: a pilot comparative randomized trial. Open
Background: Surgical management of a child is a life stage in its own right. It generates anxiety for the child and their parents. The management of preoperative anxiety is a major issue in improving the quality of care and avoiding potent…
View article: Evaluating the Effects of Mental Health e‐Learning on the Knowledge, Attitudes and Practices of Primary Healthcare Professionals in Mali. A Pilot Study
Evaluating the Effects of Mental Health e‐Learning on the Knowledge, Attitudes and Practices of Primary Healthcare Professionals in Mali. A Pilot Study Open
Background Despite their high prevalence and significant burden, mental disorders remain grossly under‐diagnosed and under‐treated. In low‐and‐middle‐income countries, such as Mali, integrating mental health services into primary care is t…
View article: Influence of clinical risk factors for preterm premature rupture of membranes (PPROM) on the elastic strength of fetal membranes at term: A prospective study
Influence of clinical risk factors for preterm premature rupture of membranes (PPROM) on the elastic strength of fetal membranes at term: A prospective study Open
Introduction Premature rupture of membranes (PROM) before 37 weeks of gestation is a common obstetrical event, whose pathophysiology is still poorly understood. Our objective was to study the mechanical strength of fetal membranes in women…
View article: Perceptions and experiences of living with dementia in sub‐Saharan Africa: a systematic review of qualitative studies
Perceptions and experiences of living with dementia in sub‐Saharan Africa: a systematic review of qualitative studies Open
Background In sub‐Saharan Africa (SSA), the number of people living with dementia is expected to double every 20 years, from 2.7 to 7.6 million. Understanding beliefs, perceptions and experiences relating to dementia, care, and help‐seekin…
View article: The incidence of all‐cause dementia and Alzheimer’s disease from around the world: data from the COSMIC collaboration
The incidence of all‐cause dementia and Alzheimer’s disease from around the world: data from the COSMIC collaboration Open
Background High‐income countries (HICs) are over‐represented in current global dementia incidence rates, skewing estimates. Variance in diagnostic methods between HICs and low‐ and middle‐income countries (LMICs) is speculated to contribut…
View article: Depressive syndrome, cognitive impairment, and associated factors among community-dwelling aged persons in Cameroon
Depressive syndrome, cognitive impairment, and associated factors among community-dwelling aged persons in Cameroon Open
Background: Depressive syndrome (DS) and cognitive impairment (CI) are associated with unsuccessful aging. However, little is known about Cameroon. This study aimed to assess the factors associated with DS and CI among older adults in Came…
View article: Machine learning-based prediction of 5-year weight trajectories after bariatric surgery in adolescents: a retrospective cohort study from France and Sweden
Machine learning-based prediction of 5-year weight trajectories after bariatric surgery in adolescents: a retrospective cohort study from France and Sweden Open
Background Metabolic-bariatric surgery is an efficient therapy in selected adolescents with severe obesity. However, predicting the postoperative weight loss is challenging. A machine learning calculator predicting 5-year weight loss traje…
View article: Barriers to global engagement for African researchers: A position paper from the Alliance for Medical Research in Africa (AMedRA)
Barriers to global engagement for African researchers: A position paper from the Alliance for Medical Research in Africa (AMedRA) Open
International audience
View article: Evaluating the effects of mental health e-learning on the knowledge, attitudes and practices of allied and healthcare professionals in Senegal
Evaluating the effects of mental health e-learning on the knowledge, attitudes and practices of allied and healthcare professionals in Senegal Open
Background: Despite the widespread prevalence and substantial burden of mental disorders, they remain significantly underdiagnosed and undertreated. In low- and middle-income countries like Senegal, integrating mental health services into …
View article: Trajectory of Cognitive Decline Before and After Stroke in 14 Population Cohorts
Trajectory of Cognitive Decline Before and After Stroke in 14 Population Cohorts Open
Importance Poststroke cognitive impairment is common, but the cognitive trajectory following a first stroke, relative to prestroke cognitive function, remains unclear. Objective To map the trajectory of cognitive function before any stroke…
View article: Association and Prognostic Implications of Peripheral Arterial Disease and Calcific Aortic Stenosis
Association and Prognostic Implications of Peripheral Arterial Disease and Calcific Aortic Stenosis Open
Background Calcific aortic stenosis (AS) and peripheral artery disease (PAD) share common pathophysiological mechanisms and risk factors related to atherosclerosis. However, the prevalence of PAD and its association with mortality in patie…
View article: Changing Epidemiology of Neurological Diseases in Africa
Changing Epidemiology of Neurological Diseases in Africa Open
EDITORIAL
View article: Blood Pressure, Antihypertensive Use, and Late-Life Alzheimer and Non-Alzheimer Dementia Risk
Blood Pressure, Antihypertensive Use, and Late-Life Alzheimer and Non-Alzheimer Dementia Risk Open
Antihypertensive use was associated with decreased AD but not non-AD risk throughout late life. This suggests that treating hypertension throughout late life continues to be crucial in AD risk mitigation. A single measure of BP was not ass…
View article: Therapeutic patient education programs on diabetes in sub-Saharan Africa: A systematic review
Therapeutic patient education programs on diabetes in sub-Saharan Africa: A systematic review Open
Background Diabetes is a chronic disease associated with the potential for blindness, kidney failure, heart attacks, strokes, and lower limb amputations. The global prevalence of diabetes is rising, particularly in the sub-Saharan African …
View article: Xth International Francophone Adelf-Epiter Congress Epidemiology and Public Health
Xth International Francophone Adelf-Epiter Congress Epidemiology and Public Health Open
International audience