Marietta Charakida
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View article: The Impact of Ursodeoxycholic Acid on Fetal Cardiac Function in Women with Gestational Diabetes Mellitus: A Randomized Controlled Study (GUARDS Trial)
The Impact of Ursodeoxycholic Acid on Fetal Cardiac Function in Women with Gestational Diabetes Mellitus: A Randomized Controlled Study (GUARDS Trial) Open
Background: Gestational diabetes mellitus (GDM) is associated with subclinical alterations in fetal cardiac morphology and function. Ursodeoxycholic acid (UDCA), widely used in pregnancy for intrahepatic cholestasis, has demonstrated cardi…
View article: The Impact of Ursodeoxycholic Acid on Fetal Cardiac Function in Women with Gestational Diabetes Mellitus: A Randomized Controlled Study (GUARDS Trial)
The Impact of Ursodeoxycholic Acid on Fetal Cardiac Function in Women with Gestational Diabetes Mellitus: A Randomized Controlled Study (GUARDS Trial) Open
Background: Gestational diabetes mellitus (GDM) is associated with subclinical alterations in fetal cardiac morphology and function. Ursodeoxycholic acid (UDCA), widely used in pregnancy for intrahepatic cholestasis, has demonstrated cardi…
View article: Cardiovascular function in women with previous gestational diabetes mellitus and dysglycemia at 5 months postpartum
Cardiovascular function in women with previous gestational diabetes mellitus and dysglycemia at 5 months postpartum Open
Objective To examine the cardiovascular profile of women at 5 months postpartum who developed gestational diabetes mellitus (GDM), and to determine whether this profile differs between those with dysglycemia and those who are normoglycemic…
View article: Vascular Assessment Stratifying Preeclampsia Risk in Overweight/Obese Women
Vascular Assessment Stratifying Preeclampsia Risk in Overweight/Obese Women Open
BACKGROUND: Overweight and obesity greatly increase the risk of preeclampsia. There is a need to better risk-stratify these women in pregnancy and channel resources to those who can benefit most. METHODS: Prospective observational study of…
View article: Bacterial Acute Otitis Media Complicated with Otorrhea in a Children’s Hospital in the Era of Pneumococcal Conjugate Vaccines
Bacterial Acute Otitis Media Complicated with Otorrhea in a Children’s Hospital in the Era of Pneumococcal Conjugate Vaccines Open
Acute otitis media (AOM) is a common disease among children and can be complicated by otorrhea (AOMO). In 2010, the 13-valent Pneumococcal Conjugate Vaccine (PCV13) replaced the 7-valent vaccine (PCV7) in Greece. We aimed to describe the m…
View article: Lifestyle and Biochemical Parameters That May Hamper Immune Responses in Pediatric Patients After Immunization with the BNT162b2 mRNA COVID-19 Vaccine
Lifestyle and Biochemical Parameters That May Hamper Immune Responses in Pediatric Patients After Immunization with the BNT162b2 mRNA COVID-19 Vaccine Open
Background: The aim of this study was to evaluate whether increased body mass index (BMI) and biochemical and lifestyle parameters linked to obesity and smoke exposure disrupt immune responses of children and adolescents following vaccinat…
View article: Lifestyle & Biochemical Parameters that May Hamper Immune Responses in Pediatric Patients After Immunization with the BNT162b2 mRNA COVID-19 Vaccine
Lifestyle & Biochemical Parameters that May Hamper Immune Responses in Pediatric Patients After Immunization with the BNT162b2 mRNA COVID-19 Vaccine Open
Background: The aim of the study is to evaluate whether increased Body Mass Index (BMI), biochemical and lifestyle parameters linked to obesity and smoke exposure disrupt immune responses of children and adolescents following vaccination w…
View article: At mid-gestation, markers of placental function rather than maternal cardiac function are stronger determinants of birthweight
At mid-gestation, markers of placental function rather than maternal cardiac function are stronger determinants of birthweight Open
The findings of our study indicate a weak but significant association between maternal cardiovascular indices with placental perfusion at mid-gestation and birthweight. Our data would not support routine maternal cardiovascular assessment …
View article: Association of maternal body mass index with hemodynamic and vascular alterations at 35–37 weeks' gestation
Association of maternal body mass index with hemodynamic and vascular alterations at 35–37 weeks' gestation Open
Objective Globally, one in four pregnant women is classified as overweight or obese, based on their prepregnancy body mass index (BMI). Obese pregnant women are at increased risk of adverse pregnancy outcomes and long‐term cardiovascular d…
View article: Prevalence of Clinical and Pre-Clinical Obesity at Six Months Postpartum
Prevalence of Clinical and Pre-Clinical Obesity at Six Months Postpartum Open
View article: Beneficial Effects of a Nutraceutical Combination on Lipid Profiles in Children with Moderate and Severe Hypercholesterolemia
Beneficial Effects of a Nutraceutical Combination on Lipid Profiles in Children with Moderate and Severe Hypercholesterolemia Open
The aim of the present study was to evaluate the efficacy and safety of the long-term use of a dietary supplement containing red yeast rice (RYR), combined with other natural compounds, in children and adolescents with primary hypercholest…
View article: Beneficial Effect of a Nutraceutical, Containing Red Yeast Rice and Polycosanols, on Lipid Profile in Children with Moderate and Severe Hypercholesterolemia
Beneficial Effect of a Nutraceutical, Containing Red Yeast Rice and Polycosanols, on Lipid Profile in Children with Moderate and Severe Hypercholesterolemia Open
The aim of the present study was to evaluate the efficacy and safety of the long-term use of a dietary supplement containing red yeast rice (RYR), combined with other natural compounds, in children and adolescents with primary hypercholest…
View article: Maternal Cardiovascular and Metabolic Function Before Conception and Subsequent Development of Gestational Diabetes Mellitus
Maternal Cardiovascular and Metabolic Function Before Conception and Subsequent Development of Gestational Diabetes Mellitus Open
Aims To determine if maternal cardiovascular and metabolic indices before conception were different in women who in a subsequent singleton pregnancy developed gestational diabetes mellitus (GDM), compared to those without GDM. Methods This…
View article: Issue Information
Issue Information Open
View article: Multisystem inflammatory syndrome in children (MIS-C): A nationwide collaborative study in the Greek population
Multisystem inflammatory syndrome in children (MIS-C): A nationwide collaborative study in the Greek population Open
Multisystem inflammatory syndrome in children (MIS-C) is a rare but severe hyperinflammatory condition that may occur following SARS-CoV-2 infection. This retrospective, descriptive study of children hospitalized with multisystem inflammat…
View article: Maternal and Offspring Cardiovascular Function following Pregnancy with Hypertensive Disorder
Maternal and Offspring Cardiovascular Function following Pregnancy with Hypertensive Disorder Open
Background: Hypertensive disorders of pregnancy (HDP) have been associated with increased cardiovascular risk for the mother and her offspring. However, it remains unknown whether cardiovascular changes are present in the postpartum period…
View article: Fetal Cardiac Function at Midgestation and Subsequent Development of Preeclampsia
Fetal Cardiac Function at Midgestation and Subsequent Development of Preeclampsia Open
At midgestation, fetuses of mothers at risk of developing PE, but not those at risk of GH, have mild reduction in left ventricular myocardial function. Although absolute differences were minimal and most likely not clinically relevant, the…
View article: Fetal Cardiac Function at Midgestation in Women Who Subsequently Develop Gestational Diabetes
Fetal Cardiac Function at Midgestation in Women Who Subsequently Develop Gestational Diabetes Open
Importance Fetuses in women with gestational diabetes (GD) compared with those without GD show evidence of subclinical cardiac functional and morphological changes. However, it is uncertain whether glycemia or the adverse maternal underlyi…
View article: Prediction of future chronic hypertension from maternal characteristics in early pregnancy
Prediction of future chronic hypertension from maternal characteristics in early pregnancy Open
Background Pre-eclampsia (PE) and gestational hypertension (GH) identify women at increased risk of chronic hypertension (CH) and cardiovascular disease, but as efforts to prevent PE and GH advance, fewer women at increased cardiovascular …
View article: LONG TERM EFFECTS OF SARS-COV-2 INFECTION ON CHILDREN'S VASCULATURE
LONG TERM EFFECTS OF SARS-COV-2 INFECTION ON CHILDREN'S VASCULATURE Open
View article: Prediction of Future Chronic Hypertension from Maternal Characteristics in Early Pregnancy
Prediction of Future Chronic Hypertension from Maternal Characteristics in Early Pregnancy Open
View article: Midgestation cardiovascular phenotype in women who develop gestational diabetes and hypertensive disorders of pregnancy: comparative study
Midgestation cardiovascular phenotype in women who develop gestational diabetes and hypertensive disorders of pregnancy: comparative study Open
Objective Women with gestational diabetes mellitus (GDM) and/or hypertensive disorders of pregnancy (HDP) are at increased long‐term cardiovascular risk. Mild cardiac functional alterations have been detected in women with GDM or HDP in mi…
View article: Angle Independency of Fetal Speckle-Tracking Echocardiography: Response
Angle Independency of Fetal Speckle-Tracking Echocardiography: Response Open
View article: Ophthalmic artery Doppler at 35–37 weeks' gestation in pregnancies with small or growth‐restricted fetuses
Ophthalmic artery Doppler at 35–37 weeks' gestation in pregnancies with small or growth‐restricted fetuses Open
Objectives First, to compare the ophthalmic artery peak systolic velocity (PSV) ratio at 35–37 weeks' gestation among women who delivered small‐for‐gestational‐age (SGA) or growth‐restricted (FGR) neonates in the absence of hypertensive di…
View article: Glycoprotein acetyls:a novel inflammatory biomarker of early cardiovascular risk in the young
Glycoprotein acetyls:a novel inflammatory biomarker of early cardiovascular risk in the young Open
Background Low-grade inflammation in the young may contribute to the early development of cardiovascular disease. We assessed whether circulating levels of glycoprotein acetyls (GlycA) were better able to predict the development of adverse…
View article: Analysis of 3-Dimensional Arch Anatomy, Vascular Flow, and Postnatal Outcome in Cases of Suspected Coarctation of the Aorta Using Fetal Cardiac Magnetic Resonance Imaging
Analysis of 3-Dimensional Arch Anatomy, Vascular Flow, and Postnatal Outcome in Cases of Suspected Coarctation of the Aorta Using Fetal Cardiac Magnetic Resonance Imaging Open
Background: Identifying fetuses at risk of severe neonatal coarctation of the aorta (CoA) can be lifesaving but is notoriously challenging in clinical practice with a high rate of false positives. Novel fetal 3-dimensional and phase-contra…
View article: Three‐dimensional echocardiography and cardiac strain imaging in women with gestational diabetes mellitus
Three‐dimensional echocardiography and cardiac strain imaging in women with gestational diabetes mellitus Open
Objectives Gestational diabetes mellitus (GDM) is associated with premature cardiovascular disease and adverse cardiovascular outcome in the mother. Subclinical cardiac functional changes in the left ventricle have been reported during pre…
View article: Childhood vascular phenotypes have differing associations with prenatal and postnatal growth
Childhood vascular phenotypes have differing associations with prenatal and postnatal growth Open
Objective: In children aged 8--9 years, we examined the associations of linear and abdominal circumference growth during critical stages of prenatal and postnatal development with six vascular measurements commonly used as early markers of…
View article: Relationship between ophthalmic artery Doppler and maternal cardiovascular function
Relationship between ophthalmic artery Doppler and maternal cardiovascular function Open
Objective In mid‐gestation, the finding of an increase in the ophthalmic artery second to first peak of systolic velocity ratio (PSV ratio) provides useful prediction of subsequent development of pre‐eclampsia (PE). The objective of this s…
View article: Maternal cardiac function at 19–23 weeks' gestation in prediction of gestational diabetes mellitus
Maternal cardiac function at 19–23 weeks' gestation in prediction of gestational diabetes mellitus Open
Objectives To examine differences in maternal cardiovascular indices at 19–23 weeks' gestation between pregnancies that develop gestational diabetes mellitus (GDM) and those without GDM, and to determine whether such cardiovascular changes…