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View article: Impact of blood centrifugation on the parameters of thrombin generation assay revisited to look for possible revision of the current guidance
Impact of blood centrifugation on the parameters of thrombin generation assay revisited to look for possible revision of the current guidance Open
View article: External quality assessment of the manual tilt tube technique for prothrombin time testing: a report from the IFCC-SSC/ISTH Working Group on the Standardization of PT/INR
External quality assessment of the manual tilt tube technique for prothrombin time testing: a report from the IFCC-SSC/ISTH Working Group on the Standardization of PT/INR Open
Objectives Detailed technical instructions have been made for harmonization of the prothrombin time (PT) test using the manual tilt tube technique (MTT). The MTT has been proposed as the reference measurement procedure for PT and internati…
View article: Comparative Investigation of Thromboelastometry and Thrombin Generation for Patients Receiving Direct Oral Anticoagulants or Vitamin K Antagonists
Comparative Investigation of Thromboelastometry and Thrombin Generation for Patients Receiving Direct Oral Anticoagulants or Vitamin K Antagonists Open
Background. Alterations induced by direct oral anticoagulants (DOACs) or vitamin K antagonists (VKAs) to thromboelastometry and thrombin generation are not well defined. We performed a simultaneous investigation of thromboelastometry and t…
View article: D-dimer for patients on VKA vs DOAC: impact on the validity of D-dimer to make decision for extended anticoagulation
D-dimer for patients on VKA vs DOAC: impact on the validity of D-dimer to make decision for extended anticoagulation Open
View article: Testosterone Therapy Does Not Affect Coagulation in Male Hypogonadism: A Longitudinal Study Based on Thrombin Generation
Testosterone Therapy Does Not Affect Coagulation in Male Hypogonadism: A Longitudinal Study Based on Thrombin Generation Open
Context Testosterone therapy has been variably associated with increased thrombotic risk but investigations of global coagulation in this setting are lacking. Objective This work aimed to compare global coagulation of hypogonadal men befor…
View article: Predictive parameters for spontaneous joint bleeding during emicizumab prophylaxis
Predictive parameters for spontaneous joint bleeding during emicizumab prophylaxis Open
Emicizumab is approved for prophylaxis of patients with hemophilia A (HA). Despite its efficacy in reducing bleeding, some patients on emicizumab still experience hemarthrosis, but no tool is yet available to identify those at a higher ris…
View article: COVID-19. Comparison of D-dimer levels measured with 3 commercial platforms
COVID-19. Comparison of D-dimer levels measured with 3 commercial platforms Open
D-dimer (DD) is used as a biomarker for prognosis and to assess for thrombosis risk in COVID-19 • Information on comparison of DD levels as measured by different commercial platforms is lacking • We compared DD values measured with three w…
View article: PB0683 Patients at Higher Risk of Spontaneous Joint Bleeding during Emicizumab Prophylaxis: A Study on Global Coagulation Assays and Arthropathy Scores
PB0683 Patients at Higher Risk of Spontaneous Joint Bleeding during Emicizumab Prophylaxis: A Study on Global Coagulation Assays and Arthropathy Scores Open
View article: Characterization of Immunogenicity and Safety of COVID-19 mRNA-1273 in HIV-Positive Italian Patients with Hemophilia: A Prospective Single-Center Cohort Study
Characterization of Immunogenicity and Safety of COVID-19 mRNA-1273 in HIV-Positive Italian Patients with Hemophilia: A Prospective Single-Center Cohort Study Open
To characterize the immunogenicity of mRNA-1273 (Moderna, Cambridge, MA, USA) vaccine in HIV-positive hemophilic patients during the third COVID-19 wave in Italy and to investigate biomarkers of coagulation and endothelial perturbation bef…
View article: Laboratory Diagnosis of Antiphospholipid Syndrome in Anticoagulated Patients
Laboratory Diagnosis of Antiphospholipid Syndrome in Anticoagulated Patients Open
The laboratory diagnosis of antiphospholipid syndrome (APS) requires the measurement of solid-phase antibodies to cardiolipin or β2-Glycoprotein-I and the search for lupus anticoagulant (LA). The diagnosis of patients whilst on anticoagula…
View article: Risk of relapse after SARS-CoV-2 vaccine in the Milan cohort of thrombotic thrombocytopenic purpura patients
Risk of relapse after SARS-CoV-2 vaccine in the Milan cohort of thrombotic thrombocytopenic purpura patients Open
Not available.
View article: Clinical and genetic determinants of the fatty liver–coagulation balance interplay in individuals with metabolic dysfunction
Clinical and genetic determinants of the fatty liver–coagulation balance interplay in individuals with metabolic dysfunction Open
In individuals with metabolic alterations at risk of metabolic fatty liver disease, there is a tendency toward heightened blood coagulation (clotting), but the cause and the impact on the progression of liver disease remain unclear. Here w…
View article: Lung Transplantation and Extracorporeal Photopheresis as Induction Therapy in Cystic Fibrosis Patients: Immune System Profile Changes
Lung Transplantation and Extracorporeal Photopheresis as Induction Therapy in Cystic Fibrosis Patients: Immune System Profile Changes Open
View article: Massive cerebral venous thrombosis due to vaccine-induced immune thrombotic thrombocytopenia
Massive cerebral venous thrombosis due to vaccine-induced immune thrombotic thrombocytopenia Open
Not available.
View article: Pro-coagulant imbalance in patients with community acquired pneumonia assessed on admission and one month after hospital discharge
Pro-coagulant imbalance in patients with community acquired pneumonia assessed on admission and one month after hospital discharge Open
Objectives Patients hospitalized because of community-acquired-pneumonia (CAP) are at risk of cardiovascular diseases. Although plasma procoagulant imbalance play a role, mechanisms are not completely understood. We aimed to investigate wh…
View article: No changes of parameters nor coagulation activation in healthy subjects vaccinated for SARS-Cov-2
No changes of parameters nor coagulation activation in healthy subjects vaccinated for SARS-Cov-2 Open
View article: Evaluation of procoagulant imbalance in Cushing’s syndrome after short- and long-term remission of disease
Evaluation of procoagulant imbalance in Cushing’s syndrome after short- and long-term remission of disease Open
View article: Procoagulant Imbalance in Klinefelter Syndrome Assessed by Thrombin Generation Assay and Whole-Blood Thromboelastometry
Procoagulant Imbalance in Klinefelter Syndrome Assessed by Thrombin Generation Assay and Whole-Blood Thromboelastometry Open
Context Klinefelter syndrome (KS) is a condition at increased risk of thrombosis compared to 46,XY men. Objective This work aimed to investigate the coagulation balance of KS patients by thrombin generation assay (TGA) and thromboelastomet…
View article: Procoagulant imbalance in patients with non-cirrhotic chronic hepatitis C (CHC) improves six months after eradication with direct-acting antiviral agents (DAAs) and likely correlates with liver fibrosis
Procoagulant imbalance in patients with non-cirrhotic chronic hepatitis C (CHC) improves six months after eradication with direct-acting antiviral agents (DAAs) and likely correlates with liver fibrosis Open
View article: Hemostatic abnormalities in patients with Ehlers–Danlos syndrome
Hemostatic abnormalities in patients with Ehlers–Danlos syndrome Open